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The map label for this gene is tpx

Identifier: 15672286

GI number: 15672286

Start: 301726

End: 302208

Strand: Direct

Name: tpx

Synonym: L101699

Alternate gene names: 15672286

Gene position: 301726-302208 (Clockwise)

Preceding gene: 15672285

Following gene: 15672287

Centisome position: 12.75

GC content: 33.75

Gene sequence:

>483_bases
ATGCCAATGAATATCACATCTCATGGTGAAAAAATAGCAACACTAAATCCGCCAATAAGTGGTGATGCACCTGATTTTGA
ACTGACAGATTTAAAAGGAAATAAAATTAAATTATCAAAACTTGAAAAACCTGTTCTGATTAGTGTTTTTCCTGATATTA
ATACTAGAGTTTGTTCACTTCAAACCAAACATTTTAATCTTGAAGCAGCAAAACATTCTGAAATTGACTTTTTGAGTATT
TCAAATAATACAGCAGATGAGCAAAAAAATTGGTGTGCAACCGAAGGTGTTGACATGACAATTCTTGCTGATGATGGAAC
TTTTGGAAAGGCTTATGGTCTTATTTTAAATGGTGGTCCTCTTGAAGGACGTCTTGCCAGAAGCGTCTTTGTTGTGAAAA
ATGGTCAAATTGTCTATAGTGAAGTTTTGTCAGAGCTTTCTGATGAACCAAATTATGAAAAAGCACTAGCAGCTACTAAA
TAG

Upstream 100 bases:

>100_bases
TAGAAAGTCAATATTTAACAGTAAAATATGAGCAATAAGAGCCAAATGAGTTGAGATTCTATGATAAAATGAAGTCATAA
AGATTAACAAAGGAGCATTA

Downstream 100 bases:

>100_bases
TTATAAATGACAAAATAGGGGATAATTGCAATTGATGCTTGTCTTCTATTTATAAGCTGTCAACAGGCAGCTTTTTTAGT
AGTAAAAAGAATAGATGTAA

Product: thiol peroxidase

Products: oxidized thioredoxin; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MPMNITSHGEKIATLNPPISGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSI
SNNTADEQKNWCATEGVDMTILADDGTFGKAYGLILNGGPLEGRLARSVFVVKNGQIVYSEVLSELSDEPNYEKALAATK

Sequences:

>Translated_160_residues
MPMNITSHGEKIATLNPPISGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSI
SNNTADEQKNWCATEGVDMTILADDGTFGKAYGLILNGGPLEGRLARSVFVVKNGQIVYSEVLSELSDEPNYEKALAATK
>Mature_159_residues
PMNITSHGEKIATLNPPISGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSIS
NNTADEQKNWCATEGVDMTILADDGTFGKAYGLILNGGPLEGRLARSVFVVKNGQIVYSEVLSELSDEPNYEKALAATK

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1787584, Length=167, Percent_Identity=29.3413173652695, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: 2480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: 1.11.1.- [C]

Molecular weight: Translated: 17437; Mature: 17306

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMNITSHGEKIATLNPPISGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSL
CCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCEEEEE
QTKHFNLEAAKHSEIDFLSISNNTADEQKNWCATEGVDMTILADDGTFGKAYGLILNGGP
EECEEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEECCC
LEGRLARSVFVVKNGQIVYSEVLSELSDEPNYEKALAATK
CCCCEEEEEEEEECCCEEHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure 
PMNITSHGEKIATLNPPISGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSL
CCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCEEEEE
QTKHFNLEAAKHSEIDFLSISNNTADEQKNWCATEGVDMTILADDGTFGKAYGLILNGGP
EECEEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEECCC
LEGRLARSVFVVKNGQIVYSEVLSELSDEPNYEKALAATK
CCCCEEEEEEEEECCCEEHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced thioredoxin; H2O2 [C]

Specific reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA