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The map label for this gene is cheB

Identifier: 15594913

GI number: 15594913

Start: 580486

End: 581643

Strand: Direct

Name: cheB

Synonym: BB0568

Alternate gene names: 15594913

Gene position: 580486-581643 (Clockwise)

Preceding gene: 15594912

Following gene: 15594914

Centisome position: 63.74

GC content: 30.57

Gene sequence:

>1158_bases
ATGAAGATATTAGTAATTGATATTCAAGGTCTTATAAAGCAGGTTTTTGTTAGAGCTTTTTCTAAAGATAATGATGTTGA
GATATTAAATGCTGGTTTTAATTCTTTAAATCTTATTAATGTATTTTTACAAAAGTTTCCAGATTTAGTTATTATTGATG
AGAATACAGCAAGATCTAATTTTGGGAATTCTTTAAACAATGTCCTTAATAATATATCTCTTCCGGTTGTATTTATTGCT
CAAAATGAAATGTTACCAAATTTTGGATGTCTTGAGCAAAGCAAGGAAAAGGTTAAATTAATAATAAATAAGCTTAATTT
TAAGCTTACAGTTGATTTATTTCGCAGTAAGTATTTAGCTTTAATAAAGCTGGAGTTGAAAAATCTAGGCAAAAATAAAT
TAATATCTTCTTTTGAAGTTAAAAGGATTCAAGCACCCGATTTTTCTAGTAATTCTAAAGTAGAGCTGAGGGAAAATAAT
TTAAATGATTCAAGTATAAGAAAAAGTTATAGAGTTTCTGATGTTATTAATTTTGCTCCCAAAAATGATCCGGATGTTAT
TATTAAATATCAAGGCCTTATCAATAAGCACAAAACTGGTAAAATTATTGTTGTAGGCTCTTCAACGGGCGGTACAGAGG
CTTTAAGAATTTTTTTAAGGTCTTTTAAAAAAGATTCTCCCCCAATTATTATTGTTCAGCATATGCCTGGAGGATTTACA
AAATCTTTTGCAAAAAACCTAAACAATGAGTTTAATATTGATATTAAAGAAGCTGAGGATGGAGACATTCTTCGTCCAGG
TCTTGTAATAATTGCTAATGGAAGTTATCATTTGATTGTAAAATATAGTAGCGGAAATTATTTTGTAAACCTATTAGATG
GACCTCTTGTTAGTAGACATAAGCCTTCTGTGAATGTACTTTTTAGGTCTGCTGCAATGTATGCAGGCTCTAATGCTATT
GGAGTTATCCTTACAGGTATGGGAGATGATGGTGCTGTTTGTATGCTTGAAATGAAAAAAAATGGCGCTTATACTATTGC
CCAAGATCAAGAAACCTCTGTTGTTTTTGGTATGCCAATGGAAGCTATAAAAATAGGGGCTGTAGACAAAATCCTTCCTT
TAAGCGAAATAGCAGATCATGTTCTAAGGAGATCTTAA

Upstream 100 bases:

>100_bases
GTTGACATAGATGCAATAACTAAACTTATAAAATAAAGAAAATAGAAAATAGAAAATGCAGCTTTTTGGTTTTAAAGGTT
AAAAATATTAAAATATAATA

Downstream 100 bases:

>100_bases
AATGGATAATGACAATAATGGTTTTGATGCCAACGATTGTTTGGCAACCTTATTTCACAAACTTGAAGCTTTTGATGAAA
GCACAAGGCATATTTATTCA

Product: chemotaxis protein CheB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSNFGNSLNNVLNNISLPVVFIA
QNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLALIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENN
LNDSSIRKSYRVSDVINFAPKNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEALRIFLRSFKKDSPPIIIVQHMPGGFT
KSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSRHKPSVNVLFRSAAMYAGSNAI
GVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMPMEAIKIGAVDKILPLSEIADHVLRRS

Sequences:

>Translated_385_residues
MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSNFGNSLNNVLNNISLPVVFIA
QNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLALIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENN
LNDSSIRKSYRVSDVINFAPKNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEALRIFLRSFKKDSPPIIIVQHMPGGFT
KSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSRHKPSVNVLFRSAAMYAGSNAI
GVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMPMEAIKIGAVDKILPLSEIADHVLRRS
>Mature_385_residues
MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSNFGNSLNNVLNNISLPVVFIA
QNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLALIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENN
LNDSSIRKSYRVSDVINFAPKNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEALRIFLRSFKKDSPPIIIVQHMPGGFT
KSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSRHKPSVNVLFRSAAMYAGSNAI
GVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMPMEAIKIGAVDKILPLSEIADHVLRRS

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=390, Percent_Identity=32.3076923076923, Blast_Score=207, Evalue=9e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB_BORBU (Q45047)

Other databases:

- EMBL:   AE000783
- EMBL:   U60236
- PIR:   G70170
- RefSeq:   NP_212702.1
- ProteinModelPortal:   Q45047
- SMR:   Q45047
- EnsemblBacteria:   EBBORT00000008444
- GeneID:   1195415
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0568
- NMPDR:   fig|224326.1.peg.952
- TIGR:   BB_0568
- GeneTree:   EBGT00050000007077
- HOGENOM:   HBG705324
- OMA:   MYAGENA
- PhylomeDB:   Q45047
- ProtClustDB:   CLSK507669
- BioCyc:   BBUR224326:BB_0568-MONOMER
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR008248
- InterPro:   IPR000673
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876

Pfam domain/function: PF01339 CheB_methylest; SSF52738 Chemotax_RR_pGlu_Me-esterase

EC number: =3.1.1.61

Molecular weight: Translated: 42691; Mature: 42691

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 208-208 ACT_SITE 234-234 ACT_SITE 330-330

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSN
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCC
FGNSLNNVLNNISLPVVFIAQNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLA
CCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHEECCCEEEEEEHHHCCEEE
LIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENNLNDSSIRKSYRVSDVINFAP
EEEEEHHHCCHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
KNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEALRIFLRSFKKDSPPIIIVQHMPGGFT
CCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
KSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSRH
HHHHHHCCCEEEEEEEECCCCCEECCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCCC
KPSVNVLFRSAAMYAGSNAIGVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMPM
CCCCEEEEEEHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEECCCCCEEEECCCH
EAIKIGAVDKILPLSEIADHVLRRS
HHEEECCHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSN
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCC
FGNSLNNVLNNISLPVVFIAQNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLA
CCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHEECCCEEEEEEHHHCCEEE
LIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENNLNDSSIRKSYRVSDVINFAP
EEEEEHHHCCHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
KNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEALRIFLRSFKKDSPPIIIVQHMPGGFT
CCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
KSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSRH
HHHHHHCCCEEEEEEEECCCCCEECCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCCC
KPSVNVLFRSAAMYAGSNAIGVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMPM
CCCCEEEEEEHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEECCCCCEEEECCCH
EAIKIGAVDKILPLSEIADHVLRRS
HHEEECCHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685