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The map label for this gene is cheA [H]

Identifier: 15594912

GI number: 15594912

Start: 578277

End: 580421

Strand: Direct

Name: cheA [H]

Synonym: BB0567

Alternate gene names: 15594912

Gene position: 578277-580421 (Clockwise)

Preceding gene: 15594911

Following gene: 15594913

Centisome position: 63.5

GC content: 32.35

Gene sequence:

>2145_bases
ATGGATAGTAGTGATGTTATTGATAAATTTAAGAATTCCTTTAAGGAAGAATCAATAGAAAATATTTCAGATATTGAGCA
AGCGCTTCTTAATCTTGAGGTAAGCTCAGATCAAGATATTGTTAATTCTATTTTTAGAAATTTACATACCATAAAGGGAA
GTTCTGGTATGTTTGGCTTTAATTTTACAGCATCGCTTGTCCACGAAATAGAAACAGTTCTTGATGTTGTAAAAAATGGT
AAGGCTGCTTTTAATCAGGCGGCTATTGATGCTACCTTAATGTCTGTTGATTTTATTAGAGAGCTTATTGAAGGCGATGA
AGTAATTTCTGAGATCGACTTTGATAAGCGTAAACAGTTTTTGGTAAATGAAATTAGAAAGGTTCTTGATATTTCTAATG
ATGTTAAGGGAGCTTTTCAAGAAGCTTTAGAAAATGATTTTTCAAAGTCTGATAACAGTTCGGTTTTGGAAGAGTCTGTT
AAAGTAAATTCAGAGAATAAATTTGATGATGAGGCTTTGCAGTCTGAATTTAAGAGTTACAAAATTCTTTTTTCTCCGGC
TAAGGGTATTTTGTTTCATGGGCACAAGCCTATAAATTTATTGAGCAAGTTGATTAATTTGGGTAGTGGTTATGTTAGGG
CCAAAGTAGATAACATTCCTGATTTAGAGCTTATCTCTCCTGATAATGTTTATGTTGATTGGGAGATAAGGTTAGATACA
GAAGAGAGTAGAGAGAGCATTGAAGATATTTTTACATTTTTAGATTCTCAATCAAAAATTGATATTCAAGAATTGGATAA
ATGTTTAGAGGCAAATGAAGGTGATAATGTAGAGTCTAAAAATTTTAATTTGTTGCACTTGGACAGAAACAGCAAAGACT
TGACTAATTCTTCATTTGAAAAATCGGCATTTGTTGGGAAATCCTTTTTCAATGGAGATAAAAATAGATCTAATATTCAA
GATGATACTGCTAGAAGCAAGGTTAATATTGCTAGTATTAAGGTGGATTCTAAAAAGCTTGATCATTTGGTAAATCTTGT
TGGAGAACTTGTTACAATACAATCAAAACTTTCAAAAGAAGCTGAAAATAGGAATAGTAATATTTTAAATTCAATATCAG
CAGAATTTTCTTTGCTTATTAATGAGCTTAGGGATTATACAACAGGGCTTAGAACAGTTCCTATTGAGATTTTGTTTGTA
AAATTTCAAAGGATAGTAAAAGATCTATCTACTAGCCTTGGTAAGTCAATTCTTTATCATGCTTCTGGAGGCGACACTGT
TCTTGACAAAAGTATTATTGAAAAGCTAAATGAACCTTTAGTTCATTTAATTCGCAACTCAATAGATCATGGAATTGAAT
CGGCTCAAGAGAGAGAAAGTTTAGGTAAAGATCCCAAAGGTATTATTAAGCTTTCAGCGTGTCAATCTGGGGATTCTGTT
ATTGTTATTATTGAGGATGACGGAAGAGGGCTTGATAAGAATAAAATACTTAAAAAAGCTATAGAGCGCAATATAATTTC
TGATTCAGTTGCCAAAACCTTATCAGAGATTGATGTTTATAATTTGATTTTTGAGCCTGGATTTTCAACTGCAAGTTCTG
TTACTGATATATCAGGTCGTGGAGTTGGCATGGATGTTGTCAAAAAACAGGTTGAATCTTTAAGGGGGCATGTTGTACTT
GAAAGTGAATTTGGTAAATATACTAGAATCAAGTTAATTTTTCCATTGACTTTGGCTATTATTGAGGGTTGGCTTGTTAG
AGTAAAAGATGAGCATTTTATTGTTCCTCTTTCTAATGTTGAATCTTGTTTAGAATCTAATAAGTTAATTTCTCAAATAG
ATGGAATTGAGACTAAAAGCAATGTAATGAATTATAGGGGCAGCATGATTAGTTATATTAGGCTTAGAGAGTTTTTTCAG
GTTTCTAGCGAGAAGAGTTTAAGTGAGCAAGTTGTTGTTGTAAATACAAATAGTGGGAAAATGGGCATTGTGGTTGACGA
AGTTTTGGGTCAACATCAAACTGTCATAAAGGCTTTGGGTAAAATTTATTCTCGAGTAGAAGGGGTTTCTGGAGCTACTA
TACTTGGTGATGGAAGTTTGGCTTTGGTTGTTGACATAGATGCAATAACTAAACTTATAAAATAA

Upstream 100 bases:

>100_bases
AAGTTCATTAATATATGGCGGGTTTTTAGTAGATATTGAAGATGTTGATAGCTTTGATTTAGGACTTAATTTAGTTGGAT
TTTAGATTTAAGGAAAGCTT

Downstream 100 bases:

>100_bases
AGAAAATAGAAAATAGAAAATGCAGCTTTTTGGTTTTAAAGGTTAAAAATATTAAAATATAATAATGAAGATATTAGTAA
TTGATATTCAAGGTCTTATA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MDSSDVIDKFKNSFKEESIENISDIEQALLNLEVSSDQDIVNSIFRNLHTIKGSSGMFGFNFTASLVHEIETVLDVVKNG
KAAFNQAAIDATLMSVDFIRELIEGDEVISEIDFDKRKQFLVNEIRKVLDISNDVKGAFQEALENDFSKSDNSSVLEESV
KVNSENKFDDEALQSEFKSYKILFSPAKGILFHGHKPINLLSKLINLGSGYVRAKVDNIPDLELISPDNVYVDWEIRLDT
EESRESIEDIFTFLDSQSKIDIQELDKCLEANEGDNVESKNFNLLHLDRNSKDLTNSSFEKSAFVGKSFFNGDKNRSNIQ
DDTARSKVNIASIKVDSKKLDHLVNLVGELVTIQSKLSKEAENRNSNILNSISAEFSLLINELRDYTTGLRTVPIEILFV
KFQRIVKDLSTSLGKSILYHASGGDTVLDKSIIEKLNEPLVHLIRNSIDHGIESAQERESLGKDPKGIIKLSACQSGDSV
IVIIEDDGRGLDKNKILKKAIERNIISDSVAKTLSEIDVYNLIFEPGFSTASSVTDISGRGVGMDVVKKQVESLRGHVVL
ESEFGKYTRIKLIFPLTLAIIEGWLVRVKDEHFIVPLSNVESCLESNKLISQIDGIETKSNVMNYRGSMISYIRLREFFQ
VSSEKSLSEQVVVVNTNSGKMGIVVDEVLGQHQTVIKALGKIYSRVEGVSGATILGDGSLALVVDIDAITKLIK

Sequences:

>Translated_714_residues
MDSSDVIDKFKNSFKEESIENISDIEQALLNLEVSSDQDIVNSIFRNLHTIKGSSGMFGFNFTASLVHEIETVLDVVKNG
KAAFNQAAIDATLMSVDFIRELIEGDEVISEIDFDKRKQFLVNEIRKVLDISNDVKGAFQEALENDFSKSDNSSVLEESV
KVNSENKFDDEALQSEFKSYKILFSPAKGILFHGHKPINLLSKLINLGSGYVRAKVDNIPDLELISPDNVYVDWEIRLDT
EESRESIEDIFTFLDSQSKIDIQELDKCLEANEGDNVESKNFNLLHLDRNSKDLTNSSFEKSAFVGKSFFNGDKNRSNIQ
DDTARSKVNIASIKVDSKKLDHLVNLVGELVTIQSKLSKEAENRNSNILNSISAEFSLLINELRDYTTGLRTVPIEILFV
KFQRIVKDLSTSLGKSILYHASGGDTVLDKSIIEKLNEPLVHLIRNSIDHGIESAQERESLGKDPKGIIKLSACQSGDSV
IVIIEDDGRGLDKNKILKKAIERNIISDSVAKTLSEIDVYNLIFEPGFSTASSVTDISGRGVGMDVVKKQVESLRGHVVL
ESEFGKYTRIKLIFPLTLAIIEGWLVRVKDEHFIVPLSNVESCLESNKLISQIDGIETKSNVMNYRGSMISYIRLREFFQ
VSSEKSLSEQVVVVNTNSGKMGIVVDEVLGQHQTVIKALGKIYSRVEGVSGATILGDGSLALVVDIDAITKLIK
>Mature_714_residues
MDSSDVIDKFKNSFKEESIENISDIEQALLNLEVSSDQDIVNSIFRNLHTIKGSSGMFGFNFTASLVHEIETVLDVVKNG
KAAFNQAAIDATLMSVDFIRELIEGDEVISEIDFDKRKQFLVNEIRKVLDISNDVKGAFQEALENDFSKSDNSSVLEESV
KVNSENKFDDEALQSEFKSYKILFSPAKGILFHGHKPINLLSKLINLGSGYVRAKVDNIPDLELISPDNVYVDWEIRLDT
EESRESIEDIFTFLDSQSKIDIQELDKCLEANEGDNVESKNFNLLHLDRNSKDLTNSSFEKSAFVGKSFFNGDKNRSNIQ
DDTARSKVNIASIKVDSKKLDHLVNLVGELVTIQSKLSKEAENRNSNILNSISAEFSLLINELRDYTTGLRTVPIEILFV
KFQRIVKDLSTSLGKSILYHASGGDTVLDKSIIEKLNEPLVHLIRNSIDHGIESAQERESLGKDPKGIIKLSACQSGDSV
IVIIEDDGRGLDKNKILKKAIERNIISDSVAKTLSEIDVYNLIFEPGFSTASSVTDISGRGVGMDVVKKQVESLRGHVVL
ESEFGKYTRIKLIFPLTLAIIEGWLVRVKDEHFIVPLSNVESCLESNKLISQIDGIETKSNVMNYRGSMISYIRLREFFQ
VSSEKSLSEQVVVVNTNSGKMGIVVDEVLGQHQTVIKALGKIYSRVEGVSGATILGDGSLALVVDIDAITKLIK

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=383, Percent_Identity=41.2532637075718, Blast_Score=290, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79391; Mature: 79391

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSDVIDKFKNSFKEESIENISDIEQALLNLEVSSDQDIVNSIFRNLHTIKGSSGMFGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
NFTASLVHEIETVLDVVKNGKAAFNQAAIDATLMSVDFIRELIEGDEVISEIDFDKRKQF
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LVNEIRKVLDISNDVKGAFQEALENDFSKSDNSSVLEESVKVNSENKFDDEALQSEFKSY
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHE
KILFSPAKGILFHGHKPINLLSKLINLGSGYVRAKVDNIPDLELISPDNVYVDWEIRLDT
EEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCEEEEEEEEECC
EESRESIEDIFTFLDSQSKIDIQELDKCLEANEGDNVESKNFNLLHLDRNSKDLTNSSFE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
KSAFVGKSFFNGDKNRSNIQDDTARSKVNIASIKVDSKKLDHLVNLVGELVTIQSKLSKE
HHHHHHHHHHCCCCCCCCCCCHHHHCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AENRNSNILNSISAEFSLLINELRDYTTGLRTVPIEILFVKFQRIVKDLSTSLGKSILYH
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ASGGDTVLDKSIIEKLNEPLVHLIRNSIDHGIESAQERESLGKDPKGIIKLSACQSGDSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEE
IVIIEDDGRGLDKNKILKKAIERNIISDSVAKTLSEIDVYNLIFEPGFSTASSVTDISGR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVGMDVVKKQVESLRGHVVLESEFGKYTRIKLIFPLTLAIIEGWLVRVKDEHFIVPLSNV
CCCHHHHHHHHHHHHCCEEEECCCCCEEEEEEHHHHHHHHHCCHHEEEECCEEEEEHHHH
ESCLESNKLISQIDGIETKSNVMNYRGSMISYIRLREFFQVSSEKSLSEQVVVVNTNSGK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
MGIVVDEVLGQHQTVIKALGKIYSRVEGVSGATILGDGSLALVVDIDAITKLIK
EEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHHHHC
>Mature Secondary Structure
MDSSDVIDKFKNSFKEESIENISDIEQALLNLEVSSDQDIVNSIFRNLHTIKGSSGMFGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
NFTASLVHEIETVLDVVKNGKAAFNQAAIDATLMSVDFIRELIEGDEVISEIDFDKRKQF
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LVNEIRKVLDISNDVKGAFQEALENDFSKSDNSSVLEESVKVNSENKFDDEALQSEFKSY
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHE
KILFSPAKGILFHGHKPINLLSKLINLGSGYVRAKVDNIPDLELISPDNVYVDWEIRLDT
EEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCEEEEEEEEECC
EESRESIEDIFTFLDSQSKIDIQELDKCLEANEGDNVESKNFNLLHLDRNSKDLTNSSFE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
KSAFVGKSFFNGDKNRSNIQDDTARSKVNIASIKVDSKKLDHLVNLVGELVTIQSKLSKE
HHHHHHHHHHCCCCCCCCCCCHHHHCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AENRNSNILNSISAEFSLLINELRDYTTGLRTVPIEILFVKFQRIVKDLSTSLGKSILYH
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ASGGDTVLDKSIIEKLNEPLVHLIRNSIDHGIESAQERESLGKDPKGIIKLSACQSGDSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEE
IVIIEDDGRGLDKNKILKKAIERNIISDSVAKTLSEIDVYNLIFEPGFSTASSVTDISGR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVGMDVVKKQVESLRGHVVLESEFGKYTRIKLIFPLTLAIIEGWLVRVKDEHFIVPLSNV
CCCHHHHHHHHHHHHCCEEEECCCCCEEEEEEHHHHHHHHHCCHHEEEECCEEEEEHHHH
ESCLESNKLISQIDGIETKSNVMNYRGSMISYIRLREFFQVSSEKSLSEQVVVVNTNSGK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
MGIVVDEVLGQHQTVIKALGKIYSRVEGVSGATILGDGSLALVVDIDAITKLIK
EEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]