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The map label for this gene is coxB [H]

Identifier: 15607121

GI number: 15607121

Start: 1539398

End: 1540108

Strand: Direct

Name: coxB [H]

Synonym: aq_2190

Alternate gene names: 15607121

Gene position: 1539398-1540108 (Clockwise)

Preceding gene: 15607120

Following gene: 15607122

Centisome position: 99.23

GC content: 43.6

Gene sequence:

>711_bases
ATGGAGCAAGTTATTGCACTGCCCTATAAGTGGTGGGCAGAGGCTGTAACTGTCTGGCTTATAGTAGCCGTAGTGATCTA
TTTAATCGTCGCAATACCGGGTATTTACTTCATCTACAAGTACAGGTACAAGCCCGGTGAAAGAGAAATAGGGGACCACG
ACTTTGAGGGACACATGGGCTTAGAAGCACTTCTTACCATAATTCCACTGCTTACGGTCATATTCTTAGCAACATACTCC
TTTACCATATTTAAGAAGCAAAGAACTGTACCCGACGGAGCGATGACGATTAAGGTAACCGCTTTCATGTGGGGATGGCA
GTTTGATTACCTCGACGAAAACGGAAAAGTTATAAAGACTGTGGTTACCGGATACCACGCAAACGACTACAACCTGCAGG
AATTTGAAAAGCCTGTAATACCCGCAGGTAAACCTATAAGAGCTCTGCTTACGTCTATGGACGTAATACACTCATTCTTC
GTGTTACCTGCAAGGATAACTGAAGACATGGTTCCTGGAAGAACGACATATCTGTGGTTCCAGATTAACAAGCCTGGTGA
GTACTGGGTGTTCTGCAGGGAGTACTGCGGAACAGGACACTCTCACATGTTTACTAAGTTAAAGGTTGTTCCTCCTGAGC
AATTTACAGCTTGGCTTTATGGTAAAAATGAAGTTGCTATAAAATCTAACAACAAGGAGGTAGCAAGATGA

Upstream 100 bases:

>100_bases
ATCCGACTTTGCTCTTTGGTGGTATTGGTTTTTCTGCTTTAGGTTTGGTCGTGCTATCTGGTCTTTTGATGAATAAACTT
AGGAAGAAGGAGGTGTAGTC

Downstream 100 bases:

>100_bases
GGTAAGCAGTTCACGTAGAGAAGCCATATTTTCTCGGAACTTTAAGAGAGTGGCTCTTTACTACCGATCACAAAAAGATC
GGAATACTTTACTTTACGAC

Product: cytochrome C oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMGLEALLTIIPLLTVIFLATYS
FTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKTVVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFF
VLPARITEDMVPGRTTYLWFQINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR

Sequences:

>Translated_236_residues
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMGLEALLTIIPLLTVIFLATYS
FTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKTVVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFF
VLPARITEDMVPGRTTYLWFQINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR
>Mature_236_residues
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMGLEALLTIIPLLTVIFLATYS
FTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKTVVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFF
VLPARITEDMVPGRTTYLWFQINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=159, Percent_Identity=30.8176100628931, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6226540, Length=170, Percent_Identity=30, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 27303; Mature: 27303

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMG
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCC
LEALLTIIPLLTVIFLATYSFTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKT
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEEEEEEEEEEEECCCCCEEEE
VVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFFVLPARITEDMVPGRTTYLWF
EEECCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
QINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR
EECCCCCEEEEEHHHCCCCCCCEEEEEEEECCHHHEEEEECCCEEEEECCCCCCCC
>Mature Secondary Structure
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMG
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCC
LEALLTIIPLLTVIFLATYSFTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKT
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEEEEEEEEEEEECCCCCEEEE
VVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFFVLPARITEDMVPGRTTYLWF
EEECCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
QINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR
EECCCCCEEEEEHHHCCCCCCCEEEEEEEECCHHHEEEEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA