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The map label for this gene is coxC [H]

Identifier: 15607119

GI number: 15607119

Start: 1537820

End: 1538596

Strand: Direct

Name: coxC [H]

Synonym: aq_2188

Alternate gene names: 15607119

Gene position: 1537820-1538596 (Clockwise)

Preceding gene: 15607116

Following gene: 15607120

Centisome position: 99.13

GC content: 48.13

Gene sequence:

>777_bases
ATGGCTCACACTGAAACCATGCACCACGAAGAAGTAAGTGTCTGGCCATTTGTGATCGGTATGGGGATGTTATTCGCACC
GATAGCCTTGACCGCTTACTTTGCGTGGCAAAACCACATGGCCGGACTCGTACTGGGAGGGTTGTCCCTAATCCTGATAC
TCTTCGGAGCTGCAGGTTGGGCAAACGAACACTTTACAAAGGATCGTGAACACGGACTGGGAGCACTGGGAACGTACTTC
TTCATAATCACGGAAGCTGTAATATTCGGAACGATGTTCGCAGCCTACTACACCGCAAGGGTAACTCACGCTCACGAGTG
GGCAAACTGGGTTCCTGAAGGTATAAGCCTAGCAATGGCAGGACTGCTTACCTTAATCCTGTGGGCATCTAGTTACACCA
TATGGAAAGCAGAAACAATACTTGAGGAAGAAGGTAATAATGGAAAAGCTCTCAAGTGGGTATTCTTCACCTTTGTACTG
GGACTGCTCTTCGTAATCCTTCACGTAAACGAGTGGAAGCACCTCTGGCATGAAGGATTTACCTTAAGCTCCAACATGTA
CGGAACTGGATTTTACGCACTCACGGGACTCCACACTTCACACGTCCTCCTCGGACTTATAATGCAACTCTACTGTATGT
GGCTTCTTGCAACCGGTAAGATGACTCAACTGAGACCTACGGTTCTCAGGGCTACTTCTGCATATTGGCACTTCGTAGAC
TTCATGTGGCTCCTCGTAGCAGGTTCTGTTTACATAATCGGAACCTTAGGGGTGTAA

Upstream 100 bases:

>100_bases
TAAGATTTGCTTATCTCTACATAATGCCCTTTTATACATTAAGAAGTATTAAGGAATTCAAAATATAAATGAAGATTTAA
ATCTGGTTAGGAGGTGAAGA

Downstream 100 bases:

>100_bases
GATGAGAATTCTTCTCTCTTTCCTCTTTCTTATTACTCTTGTTTTCGGAGGAGCTGTTGGACCTTCCAACAAAGCATTTG
ATGACAACGATATGTTCAAT

Product: cytochrome C oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAHTETMHHEEVSVWPFVIGMGMLFAPIALTAYFAWQNHMAGLVLGGLSLILILFGAAGWANEHFTKDREHGLGALGTYF
FIITEAVIFGTMFAAYYTARVTHAHEWANWVPEGISLAMAGLLTLILWASSYTIWKAETILEEEGNNGKALKWVFFTFVL
GLLFVILHVNEWKHLWHEGFTLSSNMYGTGFYALTGLHTSHVLLGLIMQLYCMWLLATGKMTQLRPTVLRATSAYWHFVD
FMWLLVAGSVYIIGTLGV

Sequences:

>Translated_258_residues
MAHTETMHHEEVSVWPFVIGMGMLFAPIALTAYFAWQNHMAGLVLGGLSLILILFGAAGWANEHFTKDREHGLGALGTYF
FIITEAVIFGTMFAAYYTARVTHAHEWANWVPEGISLAMAGLLTLILWASSYTIWKAETILEEEGNNGKALKWVFFTFVL
GLLFVILHVNEWKHLWHEGFTLSSNMYGTGFYALTGLHTSHVLLGLIMQLYCMWLLATGKMTQLRPTVLRATSAYWHFVD
FMWLLVAGSVYIIGTLGV
>Mature_257_residues
AHTETMHHEEVSVWPFVIGMGMLFAPIALTAYFAWQNHMAGLVLGGLSLILILFGAAGWANEHFTKDREHGLGALGTYFF
IITEAVIFGTMFAAYYTARVTHAHEWANWVPEGISLAMAGLLTLILWASSYTIWKAETILEEEGNNGKALKWVFFTFVLG
LLFVILHVNEWKHLWHEGFTLSSNMYGTGFYALTGLHTSHVLLGLIMQLYCMWLLATGKMTQLRPTVLRATSAYWHFVDF
MWLLVAGSVYIIGTLGV

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786633, Length=200, Percent_Identity=26, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 28999; Mature: 28868

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTETMHHEEVSVWPFVIGMGMLFAPIALTAYFAWQNHMAGLVLGGLSLILILFGAAGW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ANEHFTKDREHGLGALGTYFFIITEAVIFGTMFAAYYTARVTHAHEWANWVPEGISLAMA
CCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GLLTLILWASSYTIWKAETILEEEGNNGKALKWVFFTFVLGLLFVILHVNEWKHLWHEGF
HHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
TLSSNMYGTGFYALTGLHTSHVLLGLIMQLYCMWLLATGKMTQLRPTVLRATSAYWHFVD
EECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FMWLLVAGSVYIIGTLGV
HHHHHHHCCEEEEEECCC
>Mature Secondary Structure 
AHTETMHHEEVSVWPFVIGMGMLFAPIALTAYFAWQNHMAGLVLGGLSLILILFGAAGW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ANEHFTKDREHGLGALGTYFFIITEAVIFGTMFAAYYTARVTHAHEWANWVPEGISLAMA
CCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GLLTLILWASSYTIWKAETILEEEGNNGKALKWVFFTFVLGLLFVILHVNEWKHLWHEGF
HHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
TLSSNMYGTGFYALTGLHTSHVLLGLIMQLYCMWLLATGKMTQLRPTVLRATSAYWHFVD
EECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FMWLLVAGSVYIIGTLGV
HHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA