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The map label for this gene is acuC2

Identifier: 15607064

GI number: 15607064

Start: 1486808

End: 1487740

Strand: Direct

Name: acuC2

Synonym: aq_2110

Alternate gene names: NA

Gene position: 1486808-1487740 (Clockwise)

Preceding gene: 15607063

Following gene: 15607065

Centisome position: 95.84

GC content: 45.77

Gene sequence:

>933_bases
ATGAAAAAAGTCGGATTTATTTACGACGATATTTACTTGAAGCACGACTGGCCGGAACACCCGGAAAACAAAAACAGGCT
TATCTCAATCTTAGAACACGTGGAAAAATCCGGAATAAAAAAGGCACTGATTGATGTAAAACCAAGAAGGGCAAAAGTGG
AGGAAGTAGCACTCAACCACGATCCCGCTTACATTCAGGAAATTCACGACTTTTGTAAGTCAGGCGGGGGGTATTTAGAC
CCCGATACTTACGCCACTCCTGACACTTACGACGTTGCCCTTTACGCTGTGGGAGGTGTTCTTGAGGGAATAGACAGGAT
ATTGAGCGGGGAACTGGACAGGGCTTTTTGTGCTGTAAGACCTCCCGGACACCACGCGGAGTACGCAAAGGCGATGGGCT
TTTGCATATTCAACAACGTTGCCATAGGAGCACATTATTTGAGGAAAATTAAAGGAGTAAACAAAGTTTTCATAATAGAC
TTTGACGCACACCACGGGAACGGAACCCAGAAGAGCTTTTACGAAGACGACACAGTTTTTTACTTTTCCACCCACGAGTA
CCCTTTCTACCCGGGAACTGGCTCGGAAGACGAAAGGGGCGCGGGAAAGGGATACGGATACACTTACAATGTCCCAATGT
CCGCGGGAGCGGGGGACGATGAATACATCCCCGTTTACGAAAAATTACTTCCAGAATTGATGAATAGATTTTCTCCCGAC
TTTGTTCTTGTTTCCGCGGGCTACGACCTCCACAGGGATGATCCTTTAACATACCTGAACGTTTCAAATGAAGGTGTGAG
ACAGATAGTTAGGAACATTATTAAAACTTCCGATGAGCTCAACGCTCCCGTTTTGTTTGCTCTGGAAGGCGGATATAACT
TAAAAGCTCTCGGAGAGTGCGTAGTTATAACTCTGGAAGAAATGTTGAGGTGA

Upstream 100 bases:

>100_bases
TTATGTGGGAAACACTCCTTTCCATAAAGAGAGCAGGAGCGGATATGATAATAACTTACTTTGCGAAGGACGCGGCGAGA
ATGATCATTGAGGGTGAGGT

Downstream 100 bases:

>100_bases
GATGGGGAGGTTTAAGTACCGCTCCGGAAAGGTAAAGCTGGAACACCACATACTTGAAGGACTGGAAGAGTATCTAGATG
AAATACAAAAGTGGGAATGC

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKKVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNHDPAYIQEIHDFCKSGGGYLD
PDTYATPDTYDVALYAVGGVLEGIDRILSGELDRAFCAVRPPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIID
FDAHHGNGTQKSFYEDDTVFYFSTHEYPFYPGTGSEDERGAGKGYGYTYNVPMSAGAGDDEYIPVYEKLLPELMNRFSPD
FVLVSAGYDLHRDDPLTYLNVSNEGVRQIVRNIIKTSDELNAPVLFALEGGYNLKALGECVVITLEEMLR

Sequences:

>Translated_310_residues
MKKVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNHDPAYIQEIHDFCKSGGGYLD
PDTYATPDTYDVALYAVGGVLEGIDRILSGELDRAFCAVRPPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIID
FDAHHGNGTQKSFYEDDTVFYFSTHEYPFYPGTGSEDERGAGKGYGYTYNVPMSAGAGDDEYIPVYEKLLPELMNRFSPD
FVLVSAGYDLHRDDPLTYLNVSNEGVRQIVRNIIKTSDELNAPVLFALEGGYNLKALGECVVITLEEMLR
>Mature_310_residues
MKKVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNHDPAYIQEIHDFCKSGGGYLD
PDTYATPDTYDVALYAVGGVLEGIDRILSGELDRAFCAVRPPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIID
FDAHHGNGTQKSFYEDDTVFYFSTHEYPFYPGTGSEDERGAGKGYGYTYNVPMSAGAGDDEYIPVYEKLLPELMNRFSPD
FVLVSAGYDLHRDDPLTYLNVSNEGVRQIVRNIIKTSDELNAPVLFALEGGYNLKALGECVVITLEEMLR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795204, Length=331, Percent_Identity=35.3474320241692, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI30795202, Length=331, Percent_Identity=35.3474320241692, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI17158039, Length=331, Percent_Identity=35.3474320241692, Blast_Score=197, Evalue=7e-51,
Organism=Homo sapiens, GI169234807, Length=331, Percent_Identity=33.8368580060423, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI148539870, Length=331, Percent_Identity=33.8368580060423, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI153085395, Length=330, Percent_Identity=33.030303030303, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI13128864, Length=315, Percent_Identity=34.2857142857143, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI20070354, Length=322, Percent_Identity=32.2981366459627, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI62750349, Length=331, Percent_Identity=34.1389728096677, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI62750347, Length=331, Percent_Identity=34.1389728096677, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI226529806, Length=327, Percent_Identity=29.6636085626911, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI8923769, Length=280, Percent_Identity=29.2857142857143, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI13128862, Length=315, Percent_Identity=29.2063492063492, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13128860, Length=312, Percent_Identity=26.2820512820513, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI293336691, Length=312, Percent_Identity=27.8846153846154, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI262073088, Length=179, Percent_Identity=30.7262569832402, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI262073092, Length=215, Percent_Identity=30.2325581395349, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI209862883, Length=174, Percent_Identity=27.0114942528736, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI217272877, Length=174, Percent_Identity=27.0114942528736, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540334, Length=323, Percent_Identity=35.6037151702786, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17540332, Length=327, Percent_Identity=35.1681957186544, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI193206283, Length=327, Percent_Identity=35.1681957186544, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI193209491, Length=339, Percent_Identity=32.7433628318584, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17537347, Length=319, Percent_Identity=31.6614420062696, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25154020, Length=310, Percent_Identity=29.3548387096774, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25154022, Length=270, Percent_Identity=30, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17508561, Length=294, Percent_Identity=28.2312925170068, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17561978, Length=235, Percent_Identity=30.2127659574468, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17534739, Length=298, Percent_Identity=25.503355704698, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193207430, Length=292, Percent_Identity=22.9452054794521, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=309, Percent_Identity=32.6860841423948, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6323999, Length=213, Percent_Identity=32.8638497652582, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=26.3888888888889, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325325, Length=172, Percent_Identity=31.9767441860465, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325141, Length=318, Percent_Identity=24.8427672955975, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24642144, Length=327, Percent_Identity=36.085626911315, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24642146, Length=327, Percent_Identity=36.085626911315, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI281360899, Length=327, Percent_Identity=36.085626911315, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24642142, Length=327, Percent_Identity=36.085626911315, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24641720, Length=336, Percent_Identity=34.2261904761905, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360799, Length=336, Percent_Identity=34.2261904761905, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360801, Length=336, Percent_Identity=34.2261904761905, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24644244, Length=316, Percent_Identity=29.4303797468354, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24657891, Length=178, Percent_Identity=34.2696629213483, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24649807, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34830; Mature: 34830

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNH
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCC
DPAYIQEIHDFCKSGGGYLDPDTYATPDTYDVALYAVGGVLEGIDRILSGELDRAFCAVR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEC
PPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIIDFDAHHGNGTQKSFYEDDTVF
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEE
YFSTHEYPFYPGTGSEDERGAGKGYGYTYNVPMSAGAGDDEYIPVYEKLLPELMNRFSPD
EEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FVLVSAGYDLHRDDPLTYLNVSNEGVRQIVRNIIKTSDELNAPVLFALEGGYNLKALGEC
EEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHH
VVITLEEMLR
HEEEHHHHHC
>Mature Secondary Structure
MKKVGFIYDDIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNH
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCC
DPAYIQEIHDFCKSGGGYLDPDTYATPDTYDVALYAVGGVLEGIDRILSGELDRAFCAVR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEC
PPGHHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIIDFDAHHGNGTQKSFYEDDTVF
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEE
YFSTHEYPFYPGTGSEDERGAGKGYGYTYNVPMSAGAGDDEYIPVYEKLLPELMNRFSPD
EEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FVLVSAGYDLHRDDPLTYLNVSNEGVRQIVRNIIKTSDELNAPVLFALEGGYNLKALGEC
EEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHH
VVITLEEMLR
HEEEHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]