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The map label for this gene is spsB

Identifier: 16519702

GI number: 16519702

Start: 520682

End: 521911

Strand: Reverse

Name: spsB

Synonym: NGR_a04040

Alternate gene names: 16519702

Gene position: 521911-520682 (Counterclockwise)

Preceding gene: 16519701

Following gene: 16519703

Centisome position: 97.34

GC content: 59.92

Gene sequence:

>1230_bases
ATGCCTAAGGTCACGGTACTCGATGTCAGGCTGTATGGGGAACCGGTTTCGACCCTGACGAATCTGCAGGACGGGCGCAC
CATCTTCGCGTTCAACGAGGCTTATATCGAAGACGAAAAGCGGCCGACGCTTAGCCTGTCCCTGAAAGACCCGTTCGGGG
CGCTCATTACGAAGTTCAGGCCGTACAACATGGTGGTCCCGCCCTTCTTCTCGAACCTACTGCCAGAAGGACCGCTGCGC
AAATACCTCGCTGATCGTGCGGGTGTGAAGCCGTCGCGTGAATTCCTCCTGCTCTGGATGCTCGGCCGCGACCTGCCTGG
GGCTGTGACGGTGCATCCCTCCGAAGGGGATGACGCGCCTCCGGATGACGAGCAGGCTATCGTCGAAGCGCGGCCGAACG
CGCTACGCTTTTCGCTGGCAGGTGTGCAGCTGAAGTTCTCGGCCTTTAAGAACGACAAAAAGGGCGGCGGCTTGACCATT
CCGGCCGAGGGCACGGGTGGCTCGTGGATCGTGAAGCTGCCGTCTCAGCAATATAGCGGCGTGCCCGAGAATGAGTTCGC
GATGATGACCATCGCCCGCATGATGGGTATGGACGTGCCTGAGCTCCAGCTGGTTGATCTCGACGCCGTAAGCGGCCTGC
CGCAGGGGGTGGGTGAACTGCACGGGCAGGCGCTGGCGATCAAGCGTTTTGACCGCACGCCGGAGGGAGCGGTGCATATC
GAGGACTTTGCGCAAGTCTTCGGCGTCTTTCCCGACCACAAATACGATAAGGGCAATTACCGGATGATCGGCCGCGTGCT
GGGGATCGAAACCAGCACGGCCGACGTGGCGGAATTCATCCGGCGTCTAGTCTTCAGCACGCTAATCGGCAATGGCGACA
TGCACCTGAAGAACTGGTCGCTCATCTATCCTGATCGCCGCACCCCTGCGCTCTCGCCAGCGTATGACTTGTTGTCGACT
ATCCCTTATATCGAGGGGGAAGATACGGCGGCGCTCAATTTCTCCCGCACAAAAAAGATGGCGGCGCTGTCCAAGGACGA
GCTGGCGCATCTGGCTGCGAAAGCGGAGCTTTCCGAAAAGCTGGTGATCGACACGGCGCGCGAGACGGTTGAACGTTTTA
GGGCGGTATGGGAGGCGGAAAAGAAAAATCTGCCGATGGCCGCCAAGGTCGCCGACACGATCGATACGCACGCACCGACG
GTCGAGCTGTATCGTGAGTTCGCGAAGTAG

Upstream 100 bases:

>100_bases
ATCGCACATGCCGTAAGACACCTACGCAACGCCGCGGTGCACCGCGACCGTGACGACGCGGTCCCTCGCTCGGCCTATGC
GCTGGATGAGGAAGACGATA

Downstream 100 bases:

>100_bases
TGCCTTGCGGCTCGGCATTCAAATTATCGAGCCTTGCTGTATATTCAAGGCGTTAGCCCATCCAAAGCATGGCCGTTGGT
TCGAATCCCATCAAGACCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPKVTVLDVRLYGEPVSTLTNLQDGRTIFAFNEAYIEDEKRPTLSLSLKDPFGALITKFRPYNMVVPPFFSNLLPEGPLR
KYLADRAGVKPSREFLLLWMLGRDLPGAVTVHPSEGDDAPPDDEQAIVEARPNALRFSLAGVQLKFSAFKNDKKGGGLTI
PAEGTGGSWIVKLPSQQYSGVPENEFAMMTIARMMGMDVPELQLVDLDAVSGLPQGVGELHGQALAIKRFDRTPEGAVHI
EDFAQVFGVFPDHKYDKGNYRMIGRVLGIETSTADVAEFIRRLVFSTLIGNGDMHLKNWSLIYPDRRTPALSPAYDLLST
IPYIEGEDTAALNFSRTKKMAALSKDELAHLAAKAELSEKLVIDTARETVERFRAVWEAEKKNLPMAAKVADTIDTHAPT
VELYREFAK

Sequences:

>Translated_409_residues
MPKVTVLDVRLYGEPVSTLTNLQDGRTIFAFNEAYIEDEKRPTLSLSLKDPFGALITKFRPYNMVVPPFFSNLLPEGPLR
KYLADRAGVKPSREFLLLWMLGRDLPGAVTVHPSEGDDAPPDDEQAIVEARPNALRFSLAGVQLKFSAFKNDKKGGGLTI
PAEGTGGSWIVKLPSQQYSGVPENEFAMMTIARMMGMDVPELQLVDLDAVSGLPQGVGELHGQALAIKRFDRTPEGAVHI
EDFAQVFGVFPDHKYDKGNYRMIGRVLGIETSTADVAEFIRRLVFSTLIGNGDMHLKNWSLIYPDRRTPALSPAYDLLST
IPYIEGEDTAALNFSRTKKMAALSKDELAHLAAKAELSEKLVIDTARETVERFRAVWEAEKKNLPMAAKVADTIDTHAPT
VELYREFAK
>Mature_408_residues
PKVTVLDVRLYGEPVSTLTNLQDGRTIFAFNEAYIEDEKRPTLSLSLKDPFGALITKFRPYNMVVPPFFSNLLPEGPLRK
YLADRAGVKPSREFLLLWMLGRDLPGAVTVHPSEGDDAPPDDEQAIVEARPNALRFSLAGVQLKFSAFKNDKKGGGLTIP
AEGTGGSWIVKLPSQQYSGVPENEFAMMTIARMMGMDVPELQLVDLDAVSGLPQGVGELHGQALAIKRFDRTPEGAVHIE
DFAQVFGVFPDHKYDKGNYRMIGRVLGIETSTADVAEFIRRLVFSTLIGNGDMHLKNWSLIYPDRRTPALSPAYDLLSTI
PYIEGEDTAALNFSRTKKMAALSKDELAHLAAKAELSEKLVIDTARETVERFRAVWEAEKKNLPMAAKVADTIDTHAPTV
ELYREFAK

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE

Homologues:

Organism=Escherichia coli, GI1787785, Length=406, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4DM_RHISN (P55412)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_443822.1
- GeneID:   962277
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a04040
- HOGENOM:   HBG480759
- ProtClustDB:   CLSK628816
- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508
- TIGRFAMs:   TIGR03071

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N

EC number: NA

Molecular weight: Translated: 45310; Mature: 45179

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVTVLDVRLYGEPVSTLTNLQDGRTIFAFNEAYIEDEKRPTLSLSLKDPFGALITKFR
CCCEEEEEEEECCCHHHHHHCCCCCCEEEEECHHHHCCCCCCEEEEEECCCHHHHHHCCC
PYNMVVPPFFSNLLPEGPLRKYLADRAGVKPSREFLLLWMLGRDLPGAVTVHPSEGDDAP
CCCEECCHHHHHHCCCCHHHHHHHHHCCCCCCHHEEEEEECCCCCCCEEEEECCCCCCCC
PDDEQAIVEARPNALRFSLAGVQLKFSAFKNDKKGGGLTIPAEGTGGSWIVKLPSQQYSG
CCCCHHHHHCCCCEEEEEEECEEEEEEECCCCCCCCCEEEECCCCCCEEEEEECCHHCCC
VPENEFAMMTIARMMGMDVPELQLVDLDAVSGLPQGVGELHGQALAIKRFDRTPEGAVHI
CCCCHHHHHHHHHHHCCCCCCEEEEECHHHCCCCHHHHHHCCCEEEEECCCCCCCCCEEH
EDFAQVFGVFPDHKYDKGNYRMIGRVLGIETSTADVAEFIRRLVFSTLIGNGDMHLKNWS
HHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCE
LIYPDRRTPALSPAYDLLSTIPYIEGEDTAALNFSRTKKMAALSKDELAHLAAKAELSEK
EECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHH
LVIDTARETVERFRAVWEAEKKNLPMAAKVADTIDTHAPTVELYREFAK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
PKVTVLDVRLYGEPVSTLTNLQDGRTIFAFNEAYIEDEKRPTLSLSLKDPFGALITKFR
CCEEEEEEEECCCHHHHHHCCCCCCEEEEECHHHHCCCCCCEEEEEECCCHHHHHHCCC
PYNMVVPPFFSNLLPEGPLRKYLADRAGVKPSREFLLLWMLGRDLPGAVTVHPSEGDDAP
CCCEECCHHHHHHCCCCHHHHHHHHHCCCCCCHHEEEEEECCCCCCCEEEEECCCCCCCC
PDDEQAIVEARPNALRFSLAGVQLKFSAFKNDKKGGGLTIPAEGTGGSWIVKLPSQQYSG
CCCCHHHHHCCCCEEEEEEECEEEEEEECCCCCCCCCEEEECCCCCCEEEEEECCHHCCC
VPENEFAMMTIARMMGMDVPELQLVDLDAVSGLPQGVGELHGQALAIKRFDRTPEGAVHI
CCCCHHHHHHHHHHHCCCCCCEEEEECHHHCCCCHHHHHHCCCEEEEECCCCCCCCCEEH
EDFAQVFGVFPDHKYDKGNYRMIGRVLGIETSTADVAEFIRRLVFSTLIGNGDMHLKNWS
HHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCE
LIYPDRRTPALSPAYDLLSTIPYIEGEDTAALNFSRTKKMAALSKDELAHLAAKAELSEK
EECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHH
LVIDTARETVERFRAVWEAEKKNLPMAAKVADTIDTHAPTVELYREFAK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424