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The map label for this gene is artQ

Identifier: 16273100

GI number: 16273100

Start: 1245852

End: 1246517

Strand: Reverse

Name: artQ

Synonym: HI1178

Alternate gene names: 16273100

Gene position: 1246517-1245852 (Counterclockwise)

Preceding gene: 16273101

Following gene: 16273099

Centisome position: 68.11

GC content: 39.94

Gene sequence:

>666_bases
ATGTTTTCTGACTTTCTTTCTTTAATGTTTACCGCTGCTCTAATGACTTTAGGGCTTGCGGTCTGTTCATTGCTCTTAGG
CTTATTTTTAAGCCTTATTTTTGCCGTGCTTGAAGCAAATCGCTTTGTTGGCAAGCCGATGACAGTATTTGTGGCATTAT
TACGTGGCTTACCCGAAATTATTGTTGTATTACTTGTCTATTTTGGTTCTACTGAATTAGTAGAAATGCTGACAGGAGAA
TACATTGAATTTGGGGCATTTGGCTGTGGCGTGCTTGCGCTTTCTCTTATTTTTGCAGCTTATGCTTCACAAACATTACG
CGGTGCAATTCAAGCCATACCAAAAGGACAATGGGAATCAGGTGCAGCGTTAGGCTTAAGCAAAAGCTATACGTTCATTC
ATATTGTTATGCCACAAGTATGGCGTCACGCCTTACCTGGTTTAAGCACCCAATGGCTTGTATTGCTAAAAGATACGGCA
TTGGTTTCATTAATTGGTGTGGACGATTTGATGCACCAAGCGGATCTGATTAATACCAATACACATCAGCCTTTTACTTG
GTATGGTATTGCTGCGTTAATTTATTTGGCAGTGACATTAATTAGCCAAGTTGGTATTCGAAAATTAGAGCTGCGTTTTA
CTCGTTTTGAAAGGGGCGTGAAATAA

Upstream 100 bases:

>100_bases
AAACAAAGATTTGGCTGCACAATTAAACAAAGGTTTAGCTGCAATTAAAGCAAATGGCGAATACCAAAAAATCTATGATA
AATGGATAACAAAATAATTT

Downstream 100 bases:

>100_bases
TGTTTCAAGAATATTTAAGCGTGATCGTAAAAGGGATTCCAACGAGTTTGTTGCTTACTGTCGTATCCTTACTGATTGCT
TTCTTTTTAGCCTTATTTCT

Product: arginine transporter permease subunit ArtQ

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEIIVVLLVYFGSTELVEMLTGE
YIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWESGAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTA
LVSLIGVDDLMHQADLINTNTHQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK

Sequences:

>Translated_221_residues
MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEIIVVLLVYFGSTELVEMLTGE
YIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWESGAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTA
LVSLIGVDDLMHQADLINTNTHQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK
>Mature_221_residues
MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEIIVVLLVYFGSTELVEMLTGE
YIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWESGAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTA
LVSLIGVDDLMHQADLINTNTHQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK

Specific function: Part of the ABC transporter complex ArtPIQM involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=55.9471365638767, Blast_Score=243, Evalue=8e-66,
Organism=Escherichia coli, GI1788646, Length=221, Percent_Identity=34.3891402714932, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788226, Length=223, Percent_Identity=33.1838565022422, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788645, Length=212, Percent_Identity=34.9056603773585, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787030, Length=209, Percent_Identity=30.622009569378, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787086, Length=211, Percent_Identity=31.7535545023697, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786874, Length=230, Percent_Identity=27.3913043478261, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786873, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082239, Length=173, Percent_Identity=30.0578034682081, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI48994930, Length=128, Percent_Identity=29.6875, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARTQ_HAEIN (P45090)

Other databases:

- EMBL:   L42023
- EMBL:   U17295
- PIR:   B64188
- RefSeq:   NP_439334.1
- ProteinModelPortal:   P45090
- GeneID:   950141
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1178
- NMPDR:   fig|71421.1.peg.1127
- TIGR:   HI_1178
- HOGENOM:   HBG704821
- OMA:   AMLFAVW
- ProtClustDB:   PRK11123
- BioCyc:   HINF71421:HI_1178-MONOMER
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24291; Mature: 24291

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe0ad5f4)-; HASH(0xc27d680)-; HASH(0xe0ab25c)-; HASH(0xce8d6f4)-; HASH(0xddfd904)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHH
IVVLLVYFGSTELVEMLTGEYIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWES
HHHHHHHHCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTALVSLIGVDDLMHQADLINTN
CCCCCCCCCCHHEEHHHHHHHHHHCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCC
THQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHH
IVVLLVYFGSTELVEMLTGEYIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWES
HHHHHHHHCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTALVSLIGVDDLMHQADLINTN
CCCCCCCCCCHHEEHHHHHHHHHHCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCC
THQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458