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The map label for this gene is artM

Identifier: 16273099

GI number: 16273099

Start: 1245169

End: 1245852

Strand: Reverse

Name: artM

Synonym: HI1177

Alternate gene names: 16273099

Gene position: 1245852-1245169 (Counterclockwise)

Preceding gene: 16273100

Following gene: 16273091

Centisome position: 68.07

GC content: 36.84

Gene sequence:

>684_bases
ATGTTTCAAGAATATTTAAGCGTGATCGTAAAAGGGATTCCAACGAGTTTGTTGCTTACTGTCGTATCCTTACTGATTGC
TTTCTTTTTAGCCTTATTTCTTACTTTTTTACTTTCAATGGAAAATAAATGGATAAAAAGTGCGGTCAATTTATACCTTA
CTTTATTCACAGGCACGCCACTGTTAGTACAGTTCTTTTTAATTTATGCAGGACCCGGTCAATTCCAATGGATTATTGAC
AGCCCATTATGGTATGTCTTATCCAATGCGTGGTTCTGTGCTGCATTAGCTTTAGCACTAAACAGTGCAGCCTATTCCAC
CCAATTATTTCACGGTGCAGTGAAAGCCATTCCCAAAGGACAATGGGAAAGTTGTGGCGCATTAGGATTAAACCGCATAC
AAACTTTAAAAATTTTAATTCCTTATGCCTTAAAACGTGCGTTGCCTTCTTACAGTAACGAAATTATTTTGGTATTTAAA
GGCACGGCATTAGCATCCACCATTACGATTATGGATATTATGGGTTACGCACGCCAACTCTATGGTACAGAATATGATGC
ACTCACAATTTACGGCATTGCGGGTGGTATCTATTTAATTATCACAGGCATTGCAACATTATTACTACGTAAATTAGAGA
AAAAAGTATTGGCATTTGAACGTTTTGAAGTAAGCAAAGCATAA

Upstream 100 bases:

>100_bases
GTATTGCTGCGTTAATTTATTTGGCAGTGACATTAATTAGCCAAGTTGGTATTCGAAAATTAGAGCTGCGTTTTACTCGT
TTTGAAAGGGGCGTGAAATA

Downstream 100 bases:

>100_bases
AGTGCGGTAAAATTTTTAGTGATTTTAAATCCCAATCTCCGTTGGGATTTTTTATTTTGTGATCTTGATCACATATTTTT
GATATTAAGCCATTGGAAAA

Product: arginine transporter permease subunit ArtM

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MFQEYLSVIVKGIPTSLLLTVVSLLIAFFLALFLTFLLSMENKWIKSAVNLYLTLFTGTPLLVQFFLIYAGPGQFQWIID
SPLWYVLSNAWFCAALALALNSAAYSTQLFHGAVKAIPKGQWESCGALGLNRIQTLKILIPYALKRALPSYSNEIILVFK
GTALASTITIMDIMGYARQLYGTEYDALTIYGIAGGIYLIITGIATLLLRKLEKKVLAFERFEVSKA

Sequences:

>Translated_227_residues
MFQEYLSVIVKGIPTSLLLTVVSLLIAFFLALFLTFLLSMENKWIKSAVNLYLTLFTGTPLLVQFFLIYAGPGQFQWIID
SPLWYVLSNAWFCAALALALNSAAYSTQLFHGAVKAIPKGQWESCGALGLNRIQTLKILIPYALKRALPSYSNEIILVFK
GTALASTITIMDIMGYARQLYGTEYDALTIYGIAGGIYLIITGIATLLLRKLEKKVLAFERFEVSKA
>Mature_227_residues
MFQEYLSVIVKGIPTSLLLTVVSLLIAFFLALFLTFLLSMENKWIKSAVNLYLTLFTGTPLLVQFFLIYAGPGQFQWIID
SPLWYVLSNAWFCAALALALNSAAYSTQLFHGAVKAIPKGQWESCGALGLNRIQTLKILIPYALKRALPSYSNEIILVFK
GTALASTITIMDIMGYARQLYGTEYDALTIYGIAGGIYLIITGIATLLLRKLEKKVLAFERFEVSKA

Specific function: Part of the ABC transporter complex ArtPIQM involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787086, Length=219, Percent_Identity=57.0776255707763, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1788645, Length=210, Percent_Identity=37.1428571428571, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788226, Length=220, Percent_Identity=30, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787087, Length=219, Percent_Identity=29.2237442922374, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787030, Length=214, Percent_Identity=29.4392523364486, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786874, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788646, Length=222, Percent_Identity=27.4774774774775, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARTM_HAEIN (P45089)

Other databases:

- EMBL:   L42023
- EMBL:   U17295
- PIR:   A64188
- RefSeq:   NP_439333.1
- ProteinModelPortal:   P45089
- GeneID:   950131
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1177
- NMPDR:   fig|71421.1.peg.1126
- TIGR:   HI_1177
- HOGENOM:   HBG704821
- OMA:   AGPGQFQ
- ProtClustDB:   PRK11122
- BioCyc:   HINF71421:HI_1177-MONOMER
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 25213; Mature: 25213

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe2c0d0c)-; HASH(0xafbc2f4)-; HASH(0xd1beb58)-; HASH(0xe02c808)-; HASH(0xdbbec64)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQEYLSVIVKGIPTSLLLTVVSLLIAFFLALFLTFLLSMENKWIKSAVNLYLTLFTGTP
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLVQFFLIYAGPGQFQWIIDSPLWYVLSNAWFCAALALALNSAAYSTQLFHGAVKAIPKG
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QWESCGALGLNRIQTLKILIPYALKRALPSYSNEIILVFKGTALASTITIMDIMGYARQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
YGTEYDALTIYGIAGGIYLIITGIATLLLRKLEKKVLAFERFEVSKA
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MFQEYLSVIVKGIPTSLLLTVVSLLIAFFLALFLTFLLSMENKWIKSAVNLYLTLFTGTP
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLVQFFLIYAGPGQFQWIIDSPLWYVLSNAWFCAALALALNSAAYSTQLFHGAVKAIPKG
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QWESCGALGLNRIQTLKILIPYALKRALPSYSNEIILVFKGTALASTITIMDIMGYARQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
YGTEYDALTIYGIAGGIYLIITGIATLLLRKLEKKVLAFERFEVSKA
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458