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The map label for this gene is artI

Identifier: 16273101

GI number: 16273101

Start: 1246521

End: 1247240

Strand: Reverse

Name: artI

Synonym: HI1179

Alternate gene names: 16273101

Gene position: 1247240-1246521 (Counterclockwise)

Preceding gene: 16273102

Following gene: 16273100

Centisome position: 68.15

GC content: 35.69

Gene sequence:

>720_bases
ATGAAAAAAACATTATTAACTGCCATTTTATTAGGTGCATCCGTAGCAGCAAGTGCACAAGAACTCACTTTTGCAATGCA
ACCTAGCTATCCACCATTTGAAACCACAAATGCAAAAGGCGAAATTATCGGGTTTGATGTTGATGTGACAAATGCAATTT
GTCAAGAAATTCAAGCAACCTGTAAATTCAAGAGCGAAACCTTTGATGCGTTAATTCCAAATTTAAAAGCAAAACGTTTT
GATGCAGCAATTTCCGCAATTGATATTACCGATGCTCGTGCAAAACAAGTGTTATTCTCTGATGCGTATTACGATAGCTC
TGCAAGCTATGTTGCTCTTAAAGGCAAAGCAACCTTAGAAAGTGCAAAAAATATAGGTGTTCAAAATGGTACAACATTCC
AACAATATACCGTAGCGGAAACCAAGCAATATAGTCCAAAATCCTATGCAAGTTTACAAAATGCCATTTTAGACTTAAAG
AGCGGTCGGATTGACATTATTTTTGGCGATACCGCCGTGCTCGCCGATATGATTTCCAAAGAGCCAGAAATTCAATTTAT
AGGCGAAAAAGTGACCAATAAAAAATATTTTGGTAATGGTTTAGGTATTGCAATGCACAAATCAAACAAAGATTTGGCTG
CACAATTAAACAAAGGTTTAGCTGCAATTAAAGCAAATGGCGAATACCAAAAAATCTATGATAAATGGATAACAAAATAA

Upstream 100 bases:

>100_bases
AAGGTAAAATCGTCGAAATGGGATCGGCTGATTGCTTTGAAAATCCAAAAACGGAACAATTTAAACACTATCTTTCTCAC
TAGAAAATAAGGAGCTTACG

Downstream 100 bases:

>100_bases
TTTATGTTTTCTGACTTTCTTTCTTTAATGTTTACCGCTGCTCTAATGACTTTAGGGCTTGCGGTCTGTTCATTGCTCTT
AGGCTTATTTTTAAGCCTTA

Product: arginine ABC transporter periplasmic-binding protein

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKKTLLTAILLGASVAASAQELTFAMQPSYPPFETTNAKGEIIGFDVDVTNAICQEIQATCKFKSETFDALIPNLKAKRF
DAAISAIDITDARAKQVLFSDAYYDSSASYVALKGKATLESAKNIGVQNGTTFQQYTVAETKQYSPKSYASLQNAILDLK
SGRIDIIFGDTAVLADMISKEPEIQFIGEKVTNKKYFGNGLGIAMHKSNKDLAAQLNKGLAAIKANGEYQKIYDKWITK

Sequences:

>Translated_239_residues
MKKTLLTAILLGASVAASAQELTFAMQPSYPPFETTNAKGEIIGFDVDVTNAICQEIQATCKFKSETFDALIPNLKAKRF
DAAISAIDITDARAKQVLFSDAYYDSSASYVALKGKATLESAKNIGVQNGTTFQQYTVAETKQYSPKSYASLQNAILDLK
SGRIDIIFGDTAVLADMISKEPEIQFIGEKVTNKKYFGNGLGIAMHKSNKDLAAQLNKGLAAIKANGEYQKIYDKWITK
>Mature_239_residues
MKKTLLTAILLGASVAASAQELTFAMQPSYPPFETTNAKGEIIGFDVDVTNAICQEIQATCKFKSETFDALIPNLKAKRF
DAAISAIDITDARAKQVLFSDAYYDSSASYVALKGKATLESAKNIGVQNGTTFQQYTVAETKQYSPKSYASLQNAILDLK
SGRIDIIFGDTAVLADMISKEPEIQFIGEKVTNKKYFGNGLGIAMHKSNKDLAAQLNKGLAAIKANGEYQKIYDKWITK

Specific function: Part of the ABC transporter complex ArtPIQM involved in arginine transport

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family

Homologues:

Organism=Escherichia coli, GI1787088, Length=243, Percent_Identity=46.9135802469136, Blast_Score=237, Evalue=6e-64,
Organism=Escherichia coli, GI1787085, Length=244, Percent_Identity=47.1311475409836, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1788649, Length=253, Percent_Identity=35.1778656126482, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1788648, Length=231, Percent_Identity=34.6320346320346, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1787031, Length=244, Percent_Identity=29.9180327868852, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788228, Length=247, Percent_Identity=25.9109311740891, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): ARTI_HAEIN (P45091)

Other databases:

- EMBL:   L42023
- EMBL:   U17295
- PIR:   C64188
- RefSeq:   NP_439335.1
- ProteinModelPortal:   P45091
- GeneID:   950269
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1179
- NMPDR:   fig|71421.1.peg.1128
- TIGR:   HI_1179
- HOGENOM:   HBG698334
- OMA:   ESAKNIG
- ProtClustDB:   CLSK869976
- BioCyc:   HINF71421:HI_1179-MONOMER
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313
- SMART:   SM00062
- TIGRFAMs:   TIGR01096

Pfam domain/function: PF00497 SBP_bac_3

EC number: NA

Molecular weight: Translated: 26022; Mature: 26022

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLLTAILLGASVAASAQELTFAMQPSYPPFETTNAKGEIIGFDVDVTNAICQEIQAT
CCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
CKFKSETFDALIPNLKAKRFDAAISAIDITDARAKQVLFSDAYYDSSASYVALKGKATLE
HHHCHHHHHHHHCCCHHHHHHHHHHEEECCHHHHHHHHHHHCEECCCCCEEEEECCHHHH
SAKNIGVQNGTTFQQYTVAETKQYSPKSYASLQNAILDLKSGRIDIIFGDTAVLADMISK
HHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCC
EPEIQFIGEKVTNKKYFGNGLGIAMHKSNKDLAAQLNKGLAAIKANGEYQKIYDKWITK
CCCEEEECHHHCCCEECCCCEEEEEECCCCHHHHHHHCCEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MKKTLLTAILLGASVAASAQELTFAMQPSYPPFETTNAKGEIIGFDVDVTNAICQEIQAT
CCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
CKFKSETFDALIPNLKAKRFDAAISAIDITDARAKQVLFSDAYYDSSASYVALKGKATLE
HHHCHHHHHHHHCCCHHHHHHHHHHEEECCHHHHHHHHHHHCEECCCCCEEEEECCHHHH
SAKNIGVQNGTTFQQYTVAETKQYSPKSYASLQNAILDLKSGRIDIIFGDTAVLADMISK
HHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCC
EPEIQFIGEKVTNKKYFGNGLGIAMHKSNKDLAAQLNKGLAAIKANGEYQKIYDKWITK
CCCEEEECHHHCCCEECCCCEEEEEECCCCHHHHHHHCCEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458; 10675023