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The map label for this gene is acpS

Identifier: 85859374

GI number: 85859374

Start: 1574610

End: 1574996

Strand: Direct

Name: acpS

Synonym: SYN_02779

Alternate gene names: 85859374

Gene position: 1574610-1574996 (Clockwise)

Preceding gene: 85859373

Following gene: 85859375

Centisome position: 49.53

GC content: 49.1

Gene sequence:

>387_bases
ATGGTTCATGGAACAGGGATTGATCTGGTTGATATAGACCGCCTCGAAAAAATTCTGATGAAGTGGGACATGAGCTTTCT
CAAAAAAGTCTTTTCGCCGGCGGAAATCGAATATTGCGCGAAAAGGGCGTTTCCCGCAATTCATTATGCCGCACGCTTTG
CCGCAAAGGAAAGTTTCCTGAAATCTTTAGGCATGGGGATTGGCATGGGGATTCCGCTGAAAGACATTGAAGTGCGAAAC
GATCCACTTGGCCGGCCTGTGTTGAATCTTTATGGAAAGGCTCTGGAAATCCTTGAGAAACGGGGCATCACGACTGTGCA
TGTAAGTCTTTCACACAGTCGGTCCCAGGCGGGAGCGGTTGTCATCCTGGAGGGGCTGAAGGATTGA

Upstream 100 bases:

>100_bases
TGATGTCTCTGTAATGAAAAAAACAGCGGCCGTAACTGACGCCATTCTTCATGCATAGAAATTCAAAATACCTCTCAAAA
AAAGCGGAAATCTGATCATC

Downstream 100 bases:

>100_bases
AAAAAAGTGCCGGACAAACTTCGGCCAACCTGTCGGAGTCTTAATTATTCATGAAAAAGCAGATTCTTTCCCGGAAGGCT
GAAGAAACGCTGTATATCGG

Product: Holo- synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MVHGTGIDLVDIDRLEKILMKWDMSFLKKVFSPAEIEYCAKRAFPAIHYAARFAAKESFLKSLGMGIGMGIPLKDIEVRN
DPLGRPVLNLYGKALEILEKRGITTVHVSLSHSRSQAGAVVILEGLKD

Sequences:

>Translated_128_residues
MVHGTGIDLVDIDRLEKILMKWDMSFLKKVFSPAEIEYCAKRAFPAIHYAARFAAKESFLKSLGMGIGMGIPLKDIEVRN
DPLGRPVLNLYGKALEILEKRGITTVHVSLSHSRSQAGAVVILEGLKD
>Mature_128_residues
MVHGTGIDLVDIDRLEKILMKWDMSFLKKVFSPAEIEYCAKRAFPAIHYAARFAAKESFLKSLGMGIGMGIPLKDIEVRN
DPLGRPVLNLYGKALEILEKRGITTVHVSLSHSRSQAGAVVILEGLKD

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=121, Percent_Identity=38.0165289256198, Blast_Score=86, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325025, Length=114, Percent_Identity=37.719298245614, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SYNAS (Q2LTJ7)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461576.1
- ProteinModelPortal:   Q2LTJ7
- SMR:   Q2LTJ7
- STRING:   Q2LTJ7
- GeneID:   3884333
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_02779
- NMPDR:   fig|56780.10.peg.1521
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q2LTJ7
- BioCyc:   SACI56780:SYN_02779-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14165; Mature: 14165

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHGTGIDLVDIDRLEKILMKWDMSFLKKVFSPAEIEYCAKRAFPAIHYAARFAAKESFL
CCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
KSLGMGIGMGIPLKDIEVRNDPLGRPVLNLYGKALEILEKRGITTVHVSLSHSRSQAGAV
HHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEE
VILEGLKD
EEEECCCC
>Mature Secondary Structure
MVHGTGIDLVDIDRLEKILMKWDMSFLKKVFSPAEIEYCAKRAFPAIHYAARFAAKESFL
CCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
KSLGMGIGMGIPLKDIEVRNDPLGRPVLNLYGKALEILEKRGITTVHVSLSHSRSQAGAV
HHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEE
VILEGLKD
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA