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The map label for this gene is ttuB [H]

Identifier: 78067216

GI number: 78067216

Start: 2852872

End: 2854176

Strand: Direct

Name: ttuB [H]

Synonym: Bcep18194_A5747

Alternate gene names: 78067216

Gene position: 2852872-2854176 (Clockwise)

Preceding gene: 78067215

Following gene: 78067217

Centisome position: 77.23

GC content: 65.21

Gene sequence:

>1305_bases
ATGGCAACATCGACGCAGTCGCTGCCGGGCTCGTCCGGCGCATTCGAGGAAGCAACCTACCGCAAGGTGTCGTGGCGGCT
CGTGCCGCTCCTGCTGCTGTGCTACGTGGTCGCGTATCTCGACCGCGTGAACGTCGGGTTCGCGAAGCTGCAGATGGCGA
GCGACCTGAACCTCAGCGACACCGTCTACGGGCTCGGCGCCGGGATCTTCTTCTTCGGCTACTTCCTCTTCGAAGTGCCG
AGCAACATCATCCTGCACAAGGTCGGCGCGCGCGTGTGGATCGCACGCATCATGGCGACGTGGGGCGTGATCTCGATCCT
GACGATGTTCGTCACGACGCCCACGATGTTCTACGTGATGCGCTTCCTGCTCGGCGTCGCTGAAGCGGGCTTCTTCCCCG
GCGTGATCCTCTACCTCACCTACTGGTATCCCGCGCACCGGCGCGGCCGGATGACGACGTTCTTCATGACGGCCGTCGCG
CTGTCCGGCGTGATCGGCGGGCCGCTCTCGGGCTTCATCCTGAAAGCGTTCGACGGCATCAGCGGGTGGCACGGCTGGCA
ATGGCTGTTCCTGCTCGAGGGGATCCCGTCGGTGCTGGTCGGCGTGGTCGTGTTCCTCAAGCTGGACGAGCGGATCGAGA
AGGCGAACTGGCTGACCGACGACGAAAAGGCACTGCTCACGCGCAACGTCGATGCTGAAGAAGCCACCAAGGAAGACCTG
CCGCTCGGCGCCGTGATGTCGAGCCCGCGCGTGTGGCTGATGGCGCTGATCTACTTCTCGTTCGTGATGGGGCTCTACGG
CGTCGGCTTCTGGCTGCCGACGATCATCAAGGCCACCGGCGTGACCGACACGTTCACGATCGGCCTGCTGTCCGCGATTC
CGTATGCGGCCGCAGTGGTCGCGATGATCCTGATCGCACGCAGCGCGGACCGGCACCGCGAACGCCGCTGGCACGTCGCG
ATTCCGGCCGCAATCGGTGCGCTCGGGCTCGTCCTGTCGGTGATCTGGGCGCACCAGACCGCGCTTGCGATGCTCGGCCT
CACGCTCGCGACGATCGGCATCCTGACGACGCTGCCGCTGTTCTGGAGCCTGCCGACCGCGTTCCTTGGCGGCACGGCGG
CCGCGGCCGGCATCGCGATGATCAACTCGATCGGCAACCTCGCCGGCTTCCTCAGCCCGTACATGATGGGCTGGCTCAAG
CAGGCAACGGGCGCCAACGATTCCGGCATGTACATGCTCGCCGGGTTTCTCGTGCTCGGCGGGCTGTTGGCATTGTCAGT
GCCGAAGCGACTGGTCGACAAGTAA

Upstream 100 bases:

>100_bases
ATGGGACCCAAGTAACCGCTAAAGCGCTAACTTTGATCGACCGCGAAGCATGGGACCCAAGTAACCGCTAAAGCGCTAAC
TTTGATCGACAGGAGACAAC

Downstream 100 bases:

>100_bases
CCCTGAACGCATGACGTCCTCCGGCCGATAACCGACCGACACCCGAAACGCCCCGCTGGCCGGAACCGCTCCGGCCGGCG
GGGCGTTTCTGCTTCCGCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHKVGARVWIARIMATWGVISILTMFVTTPTMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPLSGFILKAFDGISGWHGWQWLFLLEGIPSVLVGVVVFLKLDERIEKANWLTDDEKALLTRNVDAEEATKEDL
PLGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFTIGLLSAIPYAAAVVAMILIARSADRHRERRWHVA
IPAAIGALGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYMMGWLK
QATGANDSGMYMLAGFLVLGGLLALSVPKRLVDK

Sequences:

>Translated_434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHKVGARVWIARIMATWGVISILTMFVTTPTMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPLSGFILKAFDGISGWHGWQWLFLLEGIPSVLVGVVVFLKLDERIEKANWLTDDEKALLTRNVDAEEATKEDL
PLGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFTIGLLSAIPYAAAVVAMILIARSADRHRERRWHVA
IPAAIGALGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYMMGWLK
QATGANDSGMYMLAGFLVLGGLLALSVPKRLVDK
>Mature_433_residues
ATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVPS
NIILHKVGARVWIARIMATWGVISILTMFVTTPTMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVAL
SGVIGGPLSGFILKAFDGISGWHGWQWLFLLEGIPSVLVGVVVFLKLDERIEKANWLTDDEKALLTRNVDAEEATKEDLP
LGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFTIGLLSAIPYAAAVVAMILIARSADRHRERRWHVAI
PAAIGALGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYMMGWLKQ
ATGANDSGMYMLAGFLVLGGLLALSVPKRLVDK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=260, Percent_Identity=24.2307692307692, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082071, Length=413, Percent_Identity=37.2881355932203, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI2367379, Length=304, Percent_Identity=25.3289473684211, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=20.9567198177677, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789515, Length=421, Percent_Identity=23.0403800475059, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=21.4634146341463, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=326, Percent_Identity=25.4601226993865, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322025, Length=340, Percent_Identity=25, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=321, Percent_Identity=23.3644859813084, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=26.5432098765432, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=213, Percent_Identity=23.4741784037559, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=227, Percent_Identity=24.6696035242291, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=391, Percent_Identity=23.5294117647059, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584153, Length=355, Percent_Identity=22.5352112676056, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24654215, Length=346, Percent_Identity=24.2774566473988, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922400, Length=343, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20130135, Length=433, Percent_Identity=23.094688221709, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655271, Length=433, Percent_Identity=23.094688221709, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573708, Length=271, Percent_Identity=25.0922509225092, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573707, Length=271, Percent_Identity=25.0922509225092, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648416, Length=310, Percent_Identity=22.5806451612903, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356189, Length=310, Percent_Identity=22.5806451612903, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47222; Mature: 47090

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCC
>Mature Secondary Structure 
ATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH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HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]