BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is fabG

Identifier: 78067215

GI number: 78067215

Start: 2851838

End: 2852596

Strand: Direct

Name: fabG

Synonym: Bcep18194_A5746

Alternate gene names: 78067215

Gene position: 2851838-2852596 (Clockwise)

Preceding gene: 78067214

Following gene: 78067216

Centisome position: 77.2

GC content: 65.48

Gene sequence:

>759_bases
ATGCGGTTGAGCGGCAAGACGGCAATCGTCACGGGCGGTGGTTCGGGGTTCGGCGAAGGCATCGCGAAGACGTATGCGCG
CGAAGGCGCGAACGTCGTCGTCAACGACCTGAACGGCGCGGCAGCCGAGCGCGTCGCGAGCGAAATCGCGCTCACGGGCG
GCAAGGCCATCGCGGTGGCCGGCGACGTGTCGAAGCAGGACGACTGGCACGCACTGCTGCAGGCCACGCTCGACGATTTC
CACGCGGTGCAGATCGTCGTGAACAACGCAGGCACCACGCACCGCAACAAGCCGGTGCTCGACGTGACGGAAGCCGAATT
CGACCGCGTGTACGCGGTCAACATGAAGAGCCTGTTCTGGTGCGTGCAGACCTTCGTGCCGTACTTCCGCGAACAGGGCG
GCGGCGTGTTCGTGAACGTCGCGTCGACGGCCGGCGTACGGCCTCGGCCGGGCCTCGTCTGGTACAACAGCACGAAGGGC
GCGATGATCACCGCAAGCAAGTCGCTCGCGGCCGAACTCGGCGCAGATCGTATCCGCGTGAACTGCATCAACCCCGTGCT
CGGCGAAACGGCGTTGATGACCGAATTCATGGGCTGCGAGGATACCCCCGAGAACCGCAGCCGGTTCCTCGCGACGATCC
CGCTCGGCCGCTTCTCGACACCGCAAGACATCGCGAACGCCGCGCTTTACCTCGCATCCGACGAAGCCGAATTCATTACG
GGCGTCTGCCTCGAAGTCGACGGCGGGCGCTGCATCTAG

Upstream 100 bases:

>100_bases
ACGGCTGATCACGCCGCAAGCAGCATGCGGCATACGACCGGCAGCGCCCGGTCGCGTGCCGAAGCACGACGACACTCATA
TCCAGCACAGGAGACACACC

Downstream 100 bases:

>100_bases
CCGCACCGGGCTGTTCACGCGCCGAGCCGGGATTCTTCGGCAGGCACGGCATCCACGCACTGCTTCGCACGAAACCGGGC
CTGCCACTGATACGCCGGTC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALTGGKAIAVAGDVSKQDDWHALLQATLDDF
HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFREQGGGVFVNVASTAGVRPRPGLVWYNSTKG
AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPENRSRFLATIPLGRFSTPQDIANAALYLASDEAEFIT
GVCLEVDGGRCI

Sequences:

>Translated_252_residues
MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALTGGKAIAVAGDVSKQDDWHALLQATLDDF
HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFREQGGGVFVNVASTAGVRPRPGLVWYNSTKG
AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPENRSRFLATIPLGRFSTPQDIANAALYLASDEAEFIT
GVCLEVDGGRCI
>Mature_252_residues
MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALTGGKAIAVAGDVSKQDDWHALLQATLDDF
HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFREQGGGVFVNVASTAGVRPRPGLVWYNSTKG
AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPENRSRFLATIPLGRFSTPQDIANAALYLASDEAEFIT
GVCLEVDGGRCI

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.6, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=32.4, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=29.9212598425197, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.4046692607004, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=30.7377049180328, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=30.6201550387597, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=31.0043668122271, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI33667109, Length=228, Percent_Identity=29.8245614035088, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=31.7708333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=30.0469483568075, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=28.9156626506024, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=29.5336787564767, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI142976729, Length=186, Percent_Identity=27.9569892473118, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=29.3436293436293, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=246, Percent_Identity=26.4227642276423, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4557649, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310128830, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310115468, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI302344755, Length=102, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40807363, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI25282469, Length=230, Percent_Identity=24.7826086956522, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40254986, Length=163, Percent_Identity=25.7668711656442, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=38.9558232931727, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.8125, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=32.6612903225806, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.6693227091633, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.0483870967742, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.1338582677165, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=28.2868525896414, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=31.640625, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=31.0077519379845, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=29.0322580645161, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=27.8884462151394, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=26.0536398467433, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.7269076305221, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=35.4838709677419, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.4, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=34.9397590361446, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=30.3370786516854, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=29.5454545454545, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=35.5329949238579, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=31.496062992126, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=30.1470588235294, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.9242424242424, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17564282, Length=175, Percent_Identity=33.1428571428571, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=28.6792452830189, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17508895, Length=171, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=28.1481481481481, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.8195488721804, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=26.6917293233083, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.2527881040892, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=27.3764258555133, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=28.7179487179487, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=25.6603773584906, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=27.037037037037, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=27.0408163265306, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=26.9961977186312, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=22.0408163265306, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=32.3076923076923, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=26.3598326359833, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=35.3174603174603, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.984375, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=34.1269841269841, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=33.4661354581673, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.0483870967742, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.0677290836653, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=34.010152284264, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640492, Length=237, Percent_Identity=29.957805907173, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=32.4742268041237, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=32.0158102766798, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=30.8510638297872, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=30.9803921568627, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355631, Length=194, Percent_Identity=31.4432989690722, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161076933, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=186, Percent_Identity=31.1827956989247, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=26.7015706806283, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26765; Mature: 26765

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALTGGKAIAVA
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEE
GDVSKQDDWHALLQATLDDFHAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFW
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEEEECHHHHHH
CVQTFVPYFREQGGGVFVNVASTAGVRPRPGLVWYNSTKGAMITASKSLAAELGADRIRV
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHCCCCEEEE
NCINPVLGETALMTEFMGCEDTPENRSRFLATIPLGRFSTPQDIANAALYLASDEAEFIT
EECCCHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEECCCCCEEE
GVCLEVDGGRCI
EEEEEECCCCCC
>Mature Secondary Structure
MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALTGGKAIAVA
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEE
GDVSKQDDWHALLQATLDDFHAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFW
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEEEECHHHHHH
CVQTFVPYFREQGGGVFVNVASTAGVRPRPGLVWYNSTKGAMITASKSLAAELGADRIRV
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHCCCCEEEE
NCINPVLGETALMTEFMGCEDTPENRSRFLATIPLGRFSTPQDIANAALYLASDEAEFIT
EECCCHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEECCCCCEEE
GVCLEVDGGRCI
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]