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The map label for this gene is kdpD [H]

Identifier: 57650752

GI number: 57650752

Start: 2133722

End: 2136379

Strand: Direct

Name: kdpD [H]

Synonym: SACOL2070

Alternate gene names: 57650752

Gene position: 2133722-2136379 (Clockwise)

Preceding gene: 57650733

Following gene: 57650753

Centisome position: 75.95

GC content: 31.9

Gene sequence:

>2658_bases
ATGTCAAACACTGAATCGCTAAACATAGGAAAAAAGCGTGGATCTTTAACAATTTACATCGGTTACAGTCCAGGTGTTGG
TAAAACATTTGAGATGCTTTCAAATGCCATTGAACTATTTCAAAGTAACGTTGATATTAAAATAGGATATATTGAACCGC
ATCAGCGTGATGAAACAAATGCATTAGCTGAACAATTACCTAAAATCACAACCAATTTTACTAAACATGGTAGTCATCAT
TTTCAATATTTAGATGTCGACCGCATAATCGAAGAATCGCCGACAATAGTACTTATCGATGAGTTAGCACATACGAATAT
TTCTAGAGATCGTCATGAGAAACGATATATGGATATTGAAGAAATTTTAAATCATGGTATCGATGTTCATACCACTTTGA
ACATTCAACATATTGAAAGTTTAAGTAGTCAAATTGAACTGATGACCGGTGTACATGTTAAAGAACGTGTACCCGACTAT
TTCATAATGAGCGCCGATGTATTAGAAGTCGTAGATATCTCACCTGAACAATTAATTAAACGCTTAAAAGCTGGCAAGGT
ATATAAAAAGGATAGGCTAGATGTAGCATTTAGTAATTTCTTTACGTATGCCCACCTAAGCGAACTGCGTACATTGACGT
TAAGAACAGTTGCCGACTTGATGAGTGATAAAGAAAAAGTCCGACACAACCATAAAACGTCACTCAAACCTCATATTGCT
GTGGCAATTAGTGGGAGCATTTATAATGAAGCAGTAATTAAAGAGGCATTCCATATTGCTCAAAAAGAACATGCGAAGTT
CACTGCTATTTATATAGATGTATTCGAAAAAAACAGGCAATATAAAGATAGTCAAAAGCAAGTGCATCAACATCTCATGC
TTGCAAAATCATTAGGAGCAAAAGTAAAAGTAGTTTATAGCCAAACCGTTGCATTAGGATTAGACGAATGGTGTAAAAAT
CAAGATGTAACCAAATTAATTATCGGACAACATATTAGAAATAAGTGGCGAGACTTTTTCAATACACCTTTAATTGACCA
TTTAATGTCCTTTGAACATAGCTATAAAATCGAAATCGTTCCAATCAAACAAATACCTGTTGAATTGAAAATGAACAAAT
CACCCTATCGTCCTAAAGGCAAACGTTTCGCCATAGATATGTTAAAAATGATTTTGATTCAAATAATTTGTGTAATGATG
GGACTGTGGATTTATCAACTTGATAAGCATGAGTCTAGTACGATTATTTTAATGATTTTTCTCATCGGCATCATTTTATT
ATCCATTTGGACGCGGTCCTTCATCATTGGCTTTTTAGCAGCAATTATTAACGTATTTGTTTTTAATTATTTTTTTACGG
AACCTAGATATACATTTGAAGTATATCGCTTTGACTATCCTATTACATTTATCGTTAGCATTTTAACAAGTATTTTAACG
AGTGCTTTATTAAAACAAATTAAATTCCAATACTCCATTACTAAAAAGCAACTTTATCGTACAGATTTATTATTTCAATT
TAATGATTCGATTAAACAAACTTATACAGTTGAAAACTTACTAATAAATGCTGGATACCAAATTAATCAATTATTGCAAC
AATCAATTACTATATACGTTATCAATCAATCGAAAGTAATTAAAACAATACCATTGCAAAACCATATCGATAATACGACT
CAACAGCATGAACAAGCATTAAGCTGGGTAATTAAAAATGAAAGACAAGCTGGTGCAACAACAGATACATTTCCAGGCAT
TAATAAATGGTTGATACCAATTGGCACATCTCCGATTAAAGGCATTCTAGCCATTGATTACCAAAGTTCTCAAGTGATTA
ATCCATATGATGCATCAATATTAGAATCAATGTTAAATGAACTTTCTCTCGCCGTTGAAAATGTGACGTTACTTAAACAA
ACGAGAGAATCCATGTTACAGGCTGAACGTCAACTGACACATTCAAATTTTTTAAGATCAATTTCGCATGACATACGTAC
ACCGTTAACAACAATTATGGGAAATTTAGATATTTTAGTATCACATAGTAAAGATATGTCTGTCATAGAAAAGGAACAAT
TACTTGTACATAGTTTTCAAGAAAGTCAGTATTTATATCTATTAGTGACAAATATTTTATCATTAACAAAATTACAGTCA
TCAAATGTTCAGATAAAATTGCAACCTTATCTCGTTAGTGAATTAGTAGAAGAAATCGATATGATTTTAGAACGTCGCCA
TTTAAAAAAGCGTATAACTGTATCATCCTCAGTAAATTTACAGTTTATACACATTGACAGTAAGTTGATTTTACAAGCTT
TATTCAATTTGATTGAAAATGCAGTTAAACACACTTCTACTGACACCAAAATCAATTTATCTATTCGTTATGCTAGCTAT
GAACAAATCGAATTTGCCGTTATAGACGAAGGACCTGGAATTAGTTTAGAAGAACAACAAAAGATATTCGAGCCTTTTTA
CACAGGATCAAATAAATATTTTAAAGATAACCAAAAAGAAAGCATGGGACTAGGCTTATATTTAGTACAGACTATCCTAC
ACAAACATCAATCAAACTTACAATATAAACCGAACCAACCACACGGCAGTATATTCTATTTCAATATATATACAGACTTT
AACGAAGGAGACGTATAA

Upstream 100 bases:

>100_bases
AACTTAGTTATTAAGAAATCATTAAGATGTGTATGCAGAAATAAATTTTATAGCATTTAATTGTGAAGAATATTATGATA
TTGCTATCGAGGTGAAGGTT

Downstream 100 bases:

>100_bases
TGCAATCTAAAATATTGATAATTGAAGATGATCACGCAATCACACATTTACTTGATGTTGCATTAACTTTAGATTATTAC
AATGTAACTACAGCCGACAA

Product: sensor histidine kinase KdpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 885; Mature: 884

Protein sequence:

>885_residues
MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHH
FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY
FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA
VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN
QDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM
GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT
SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTT
QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ
TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS
SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASY
EQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDF
NEGDV

Sequences:

>Translated_885_residues
MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHH
FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY
FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA
VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN
QDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM
GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT
SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTT
QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ
TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS
SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASY
EQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDF
NEGDV
>Mature_884_residues
SNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHHF
QYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYF
IMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIAV
AISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKNQ
DVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMG
LWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILTS
ALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTTQ
QHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQT
RESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQSS
NVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASYE
QIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFN
EGDV

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=882, Percent_Identity=26.1904761904762, Blast_Score=357, Evalue=2e-99,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=29.4605809128631, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=28.5087719298246, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=24.7787610619469, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788279, Length=261, Percent_Identity=27.2030651340996, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=25, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=23.0452674897119, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=22.4066390041494, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 102207; Mature: 102075

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETN
CCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAEQLPKITTNFTKHGSHHFQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIE
HHHHHCCHHHHHHHHCCCCCEEEECHHHHHCCCCCEEEEECHHCCCCCHHHHHHHCCCHH
EILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYFIMSADVLEVVDISPEQLIK
HHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCHHHHHCCCHHHHHH
RLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGA
EEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHCCC
KVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIV
EEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE
PIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMGLWIYQLDKHESSTIILMIF
EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH
SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHEECCCHHHHHHHCCCEEEE
INQSKVIKTIPLQNHIDNTTQQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIK
EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC
GILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRS
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS
HHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIEN
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHHH
AVKHTSTDTKINLSIRYASYEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKE
HHHCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
SMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFNEGDV
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
SNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETN
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAEQLPKITTNFTKHGSHHFQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIE
HHHHHCCHHHHHHHHCCCCCEEEECHHHHHCCCCCEEEEECHHCCCCCHHHHHHHCCCHH
EILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYFIMSADVLEVVDISPEQLIK
HHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCHHHHHCCCHHHHHH
RLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGA
EEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHCCC
KVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIV
EEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE
PIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMGLWIYQLDKHESSTIILMIF
EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH
SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHEECCCHHHHHHHCCCEEEE
INQSKVIKTIPLQNHIDNTTQQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIK
EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC
GILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRS
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS
HHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIEN
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHHH
AVKHTSTDTKINLSIRYASYEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKE
HHHCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
SMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFNEGDV
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]