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The map label for this gene is tdk [H]

Identifier: 49188165

GI number: 49188165

Start: 5059109

End: 5059693

Strand: Reverse

Name: tdk [H]

Synonym: BAS5179

Alternate gene names: 49188165

Gene position: 5059693-5059109 (Counterclockwise)

Preceding gene: 49188166

Following gene: 49188164

Centisome position: 96.77

GC content: 39.32

Gene sequence:

>585_bases
ATGTACTTAATAAATCAGAACGGTTGGATTGAAGTGATTTGCGGTAGTATGTTTTCTGGTAAATCAGAAGAGCTTATCCG
CCGTGTTCGTCGTACGCAATTTGCGAAACAACATGCAATTGTATTTAAACCATGTATTGATAATCGCTATAGTGAAGAAG
ACGTTGTATCACATAACGGATTAAAGGTAAAAGCAGTTCCTGTTTCAGCTTCAAAAGATATATTTAAACATATCACTGAA
GAAATGGATGTAATTGCAATTGATGAAGTGCAATTCTTTGATGGGGACATTGTGGAAGTGGTGCAAGTATTGGCAAATCG
TGGCTATCGTGTCATTGTAGCTGGTTTAGACCAAGATTTCCGTGGTCTACCATTTGGACAAGTTCCTCAGCTGATGGCGA
TTGCTGAACATGTAACAAAACTACAAGCTGTATGTTCTGCATGTGGATCTCCGGCAAGTCGTACACAACGATTAATTGAT
GGAGAACCAGCGGCATTTGATGATCCAATTATTTTAGTTGGTGCTTCAGAGTCGTATGAACCACGCTGTCGTCATTGTCA
TGCAGTTCCTACAAAACAAAGATAA

Upstream 100 bases:

>100_bases
TAAAACAGGCAAGTGTATCTATTCGCTTGTCTGTTTTTTTTGCGAAAATATTATACCTTTACCCTACTTTTAACGAAAAA
GTAGATGAAAGGAGAGCTTC

Downstream 100 bases:

>100_bases
GTAAACTCGCTGTGCAAGGCGGGTTTTTTTCAGAATAGAGAGTGTGAGTGGTGTGAGCCGCTTACGCTTTTAAATAATAT
CTAGTTCCGGTGGCTAGCTC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFKHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTKQR

Sequences:

>Translated_194_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFKHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTKQR
>Mature_194_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFKHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTKQR

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=180, Percent_Identity=41.1111111111111, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17543396, Length=193, Percent_Identity=33.6787564766839, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21642; Mature: 21642

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCCCC
LKVKAVPVSASKDIFKHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDF
EEEEEEECCCHHHHHHHHHHHCCEEEECCEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
RGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHCHAVPTKQR
CHHHHCCCCCCCCC
>Mature Secondary Structure
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCCCC
LKVKAVPVSASKDIFKHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDF
EEEEEEECCCHHHHHHHHHHHCCEEEECCEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
RGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHCHAVPTKQR
CHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA