| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
Click here to switch to the map view.
The map label for this gene is purN
Identifier: 41407000
GI number: 41407000
Start: 931265
End: 931894
Strand: Direct
Name: purN
Synonym: MAP0902
Alternate gene names: 41407000
Gene position: 931265-931894 (Clockwise)
Preceding gene: 41406999
Following gene: 41407001
Centisome position: 19.28
GC content: 67.94
Gene sequence:
>630_bases GTGGTCGAACCGCTGCATGTGCCCCCCAATGCGCCGGCGCGGGTGGTGGTGCTGGCTTCGGGTACCGGATCGCTGCTCAG CTCGCTGATCGACGCCGCCGTGGGCGACTACCCGGCCCGGGTGGTCGCGGTCGGCGCCGACCGCGACTGCCTGGCCACCC AGATCGCCGCGGCCGCCTCCCTGCCCTCCTTCACCGTCCGGCTCGGCGACCACCCTGACCGCGCCGCCTGGGACGCCGCG ATCACCGAGGCCACCGCCGCCCACTCGCCCGACCTGGTGGTATCCGCAGGGTTTATGAAAATTCTTGGGCCGCAATTTCT TTCACGCTTCTACGGGCGGGTCATCAACACGCATCCGGCGCTGCTGCCAGCCTTCCCGGGCGCACATGGCGTGGCCGAAG CGTTGGCCTACGGCGTGAAAGTCACAGGCTGTACGGTGCACCTGGTGGACGCCGGGACGGACACCGGGCCGATTTTGGCT CAGCAATCCGTTCCGGTGCTCGACGGCGACGACGAACAGACGTTGCACGAACGCATCAAAGTCACCGAACGCAAGCTGCT GGTGGATGTGGTGGCTGCGATCGCGACCGGCGGCCTGACCCTGGTCGGGAGAAAAGCGACGATCGGATGA
Upstream 100 bases:
>100_bases CGGGCACTTCCCATGTGCCCCGCCGGCCCGGCGCGCCGGATTGTCGGGCTCCTCAGCGTGCCGTGACGGCACGCATCGTC GCCCGACTAGGCTCGCCGAT
Downstream 100 bases:
>100_bases AAGGCGACCAACCGATGAGCACCGACGACTGGCGGGAAAACGCCAAAAGGCCGATCCGTCGCGCCTTGATCAGCGTGTAC GACAAGACCGGTCTGGTCGA
Product: phosphoribosylglycinamide formyltransferase
Products: NA
Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]
Number of amino acids: Translated: 209; Mature: 209
Protein sequence:
>209_residues MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARVVAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAA ITEATAAHSPDLVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKVTGCTVHLVDAGTDTGPILA QQSVPVLDGDDEQTLHERIKVTERKLLVDVVAAIATGGLTLVGRKATIG
Sequences:
>Translated_209_residues MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARVVAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAA ITEATAAHSPDLVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKVTGCTVHLVDAGTDTGPILA QQSVPVLDGDDEQTLHERIKVTERKLLVDVVAAIATGGLTLVGRKATIG >Mature_209_residues MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARVVAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAA ITEATAAHSPDLVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKVTGCTVHLVDAGTDTGPILA QQSVPVLDGDDEQTLHERIKVTERKLLVDVVAAIATGGLTLVGRKATIG
Specific function: De novo purine biosynthesis; third step. [C]
COG id: COG0299
COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the GART family [H]
Homologues:
Organism=Homo sapiens, GI4503915, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29, Organism=Homo sapiens, GI209869995, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29, Organism=Homo sapiens, GI209869993, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29, Organism=Escherichia coli, GI1788846, Length=190, Percent_Identity=35.7894736842105, Blast_Score=117, Evalue=4e-28, Organism=Escherichia coli, GI1787483, Length=161, Percent_Identity=32.2981366459627, Blast_Score=89, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17567511, Length=184, Percent_Identity=36.9565217391304, Blast_Score=120, Evalue=5e-28, Organism=Drosophila melanogaster, GI24582400, Length=188, Percent_Identity=40.9574468085106, Blast_Score=137, Evalue=6e-33,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002376 - InterPro: IPR001555 - InterPro: IPR004607 [H]
Pfam domain/function: PF00551 Formyl_trans_N [H]
EC number: =2.1.2.2 [H]
Molecular weight: Translated: 21479; Mature: 21479
Theoretical pI: Translated: 6.14; Mature: 6.14
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARVVAVGADRDCLATQIAAAAS CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC LPSFTVRLGDHPDRAAWDAAITEATAAHSPDLVVSAGFMKILGPQFLSRFYGRVINTHPA CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHCCCCC LLPAFPGAHGVAEALAYGVKVTGCTVHLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIK EECCCCCHHHHHHHHHHCEEEECEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHH VTERKLLVDVVAAIATGGLTLVGRKATIG HHHHHHHHHHHHHHHCCCEEEEECCCCCC >Mature Secondary Structure MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARVVAVGADRDCLATQIAAAAS CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC LPSFTVRLGDHPDRAAWDAAITEATAAHSPDLVVSAGFMKILGPQFLSRFYGRVINTHPA CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHCCCCC LLPAFPGAHGVAEALAYGVKVTGCTVHLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIK EECCCCCHHHHHHHHHHCEEEECEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHH VTERKLLVDVVAAIATGGLTLVGRKATIG HHHHHHHHHHHHHHHCCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 3036807; 9384377 [H]