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The map label for this gene is hppA [H]

Identifier: 239616542

GI number: 239616542

Start: 150034

End: 152205

Strand: Direct

Name: hppA [H]

Synonym: Kole_0134

Alternate gene names: 239616542

Gene position: 150034-152205 (Clockwise)

Preceding gene: 239616541

Following gene: 239616543

Centisome position: 6.52

GC content: 48.3

Gene sequence:

>2172_bases
ATGAATGCTCTGTATCTCCCACTAACTGCGGGTGTTCTTTCGACCATCTTTGCATTTATCATGCTTGCCCGTACTTTGAA
ATTTTCACCCGGTAACAAGACTATGCAAAAATTATCCGGTTACGTTCAAGAAGGTGCATCTGCCTTTCTCTCTGAGGAAG
CACGCAAGATATTCCTGGTGGCCGTCTTAATAGCAGCGGCTCTGGGTATAATCTTTCAGTCGTTCAAATACCCAATCGCT
CTTCTTTTCGGTGCCCTTGTATCGGAACTCGCCGGCGTAATGGGGATGTACGCCGCGACGAGAGCAAATGCCAGGGTTAC
CCAGGGAGCTACAAAAGGATTATCTGAAGCCTTTAAGGTAGCCTTTTCCGGTGGTTCCGTCATGGGGCTCTCTGTTGCGG
GATTCTCCCTTACCGGTTTGAGCATAATAATGCTTGTTTTCAAGGATTCTTTCCTCTACAACAACATCACAGAAATATCG
CAAGCCTTCGGAAAAATATCTTTCCTTGATCCGGTTATGATAGTAAGCTCTTACTCTCTTGGTGCGAGTCTCATTGCCCT
GTTCGACAGGGTCGGAGGCGGTATGTACACAAAGGCGGCCGACATGAGTGCTGACCTTGTCGGAAAGGTGGAAGCGGGAA
TCCCCGAAGACGACCCGAGAAACCCCGCTACTATTGCCGACAACGTCGGAGACAACGTTGGAGACGTGGCCGGGCTCGGT
GCGGATATTCTCGAATCCTATGTCGCTTCTGTTGTTTCTGCCATCGTGCTTGCCATCTTCATGAAACTCGCAGACAAACA
AATGATCAATGGGCAGGTCCAATACGGGATGAGCCCTGAACAATATTACGGATTGATCCTGCTTCCAATCCTCATCGCCG
GCGTTGGTGTCCTTTCTTCGCTCGTTGGAGTGCTGGTTGTGGCAAACATGAAGGCGAAGGATGCCAGAAAAGCCCTCGGT
TTTGGTAACGTATTCACCGGTATTCTTGTCCTCGCATCAACCGCTATCGTGATCGGAATCGCCGCACCAGATTACGCATT
CAAAGATACCTTTATTCTCAACCCTGAATTCGTTTCCAGATGGAGATTGTTCTTAGCAATCGCCAGCGGTCTGATCGCCG
GGTTGATAATAAGCAAATTAAGTGAGTACTACACCTCCTACGACTACAAACCTACACAGGATCTCGCCGAAAAAACAAAA
AGCGGTGTTGCAATAAACATAACCTCTGGATTGGCGCTAGGTATGGGAAGCACGTTCTGGCCAGTAATTGTCCTGGCTAT
CGCCATTCTCGGTGCCTACTGGTCAGCGGGTGTCTATGGAATAGCAATAGCGGCCCTTGGAATGCTTTCATTCGTTGGAT
ACATTGTCAGCGTTGATAGCTATGGTCCTGTTGCTGACAACGCCGGTGGAATCGCCCAGATGGCTGAACTTGATCCAAAG
GTTCGTGAGATAACGGATAGACTTGATTCTGTCGGAAATACAACCGCTGCGATCGGTAAAGGATTCGCGATCGGTTCAGC
AGCTTTCGCGGCTCTTGCGCTCATAGTTTCTTATATATGGAGTGCCGCACATTCTGCGGAGGAAATCGTAAACAATCCTG
TAATTAATCTTGTTTCCCCCTACACAATCATTGGTTCGATCATAGGCGCAATGTTGCCTTTCTTCTTCACCTCACTGTTG
ATCCGTGGTGTCGCCGATACAGCAGATCTCATGATAACCGAAATCAGGCGACAGTTCAGAGAACATAAAGGAATTCTGAC
AGGCGAAGAAACACCTGATTATAAGAGATGTATAGAAATCACCACAAAGGGTGCGGTCAGCAGAATGCTGCTGCCCGGTA
TAATCGCAATCGCGACACCTTTTGTTGTCGGATTCCTCTTTGGTAAGGCAGCGGTTGCCGGATTGCTTCTTGGAGGCCTC
GGCAGTGCCATCATGATTGCACTGTTCACAGCGAATTCAGGTGGTGCATGGGATAACGCTAAAAAATACATTGAATCCGG
GCATTTCGGTGGAAAAGGAACGGATGTTCACTCCGCTGCGGTTGTTGGGGATACCGTCGGGGATCCTCTGAAAGATACCG
TAGGTCCATCAATGGATATTCTGATAAAGCTCATGTCTGTCGTTTCTCTCGTTTTTGGTTCATTATTCCCGGATAAACCG
TTCTTTATGTGA

Upstream 100 bases:

>100_bases
CTTTCTTACAAAGATCCCGGAGGATGTGGCTGAAAGATGGGACGTTGGGTGGAATATTTAATACCATATTTCTCTTGATT
CCTATGAAGGAGGGGAAAAA

Downstream 100 bases:

>100_bases
TTACACATATAAAACACCGGGGCAAAACTTGCCCCGGTGTTTTGCTCTAACATAAATGATATGGTATCATTTTATTCCAA
AAACAATTGTTCCATCGGAG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase; Tm-PPase [H]

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA
LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS
QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG
ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG
FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK
SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK
VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL
IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL
GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP
FFM

Sequences:

>Translated_723_residues
MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA
LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS
QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG
ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG
FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK
SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK
VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL
IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL
GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP
FFM
>Mature_723_residues
MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA
LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS
QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG
ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG
FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK
SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK
VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL
IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL
GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP
FFM

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 75818; Mature: 75818

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLV
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLIAAALGIIFQSFKYPIALLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEISQAFGKISFLDPVMIVSSYSL
HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCHHHHHHHHHH
GASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG
HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHCC
ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVGVLVVANMKAKDARKALGFGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSR
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECHHHHHH
WRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTKSGVAINITSGLALGMGSTFW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEECCCHHHCCCCHHH
PVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHH
VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSP
HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTIIGSIIGAMLPFFFTSLLIRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
TTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGLGSAIMIALFTANSGGAWDNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHH
KKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP
HHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
FFM
CCC
>Mature Secondary Structure
MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLV
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLIAAALGIIFQSFKYPIALLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEISQAFGKISFLDPVMIVSSYSL
HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCHHHHHHHHHH
GASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG
HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHCC
ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVGVLVVANMKAKDARKALGFGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSR
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECHHHHHH
WRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTKSGVAINITSGLALGMGSTFW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEECCCHHHCCCCHHH
PVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHH
VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSP
HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTIIGSIIGAMLPFFFTSLLIRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
TTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGLGSAIMIALFTANSGGAWDNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHH
KKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP
HHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
FFM
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571; 9440516; 11343697 [H]