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The map label for this gene is coaA [H]

Identifier: 227080532

GI number: 227080532

Start: 318413

End: 319540

Strand: Reverse

Name: coaA [H]

Synonym: VCM66_0304

Alternate gene names: 227080532

Gene position: 319540-318413 (Counterclockwise)

Preceding gene: 227080542

Following gene: 227080529

Centisome position: 11.05

GC content: 43.88

Gene sequence:

>1128_bases
GTGGTGCGCATTCTAGTGAATGATCTTGGGGGTTGCAACCCTTATCTTGAAAAAAAACTCAATTTTCAAAGGATTTTGCT
TGTTCGTTGTTTTTTCAGTCAAATTAGAGCGCAATCGCTAATTCTCGCATCTTTCTATTTTGTTTTATCTTGTGCTTATT
GTATTTTCGCTTTCCTTATTCTCAACCGCATGATTGAACCGATTATGAGCCCTTATTTAACCTTTGATCGCCAACACTGG
GCCCAATTGCGCAATTCAGTACCTATGACGCTCTCTGAAAGCGATCTAAAAGAGTTACAGGGCATCAATGACCATTTATC
GATGACCGAAGCGGTTGAAATCTATCTTCCCCTCGCTCGTCTACTGAATTTGTATGTGGCTGCGCGTCAAAGTCGTAATG
GTGTGTTGCATCAGTTTTTGGGTAATACCGAATCAGCACCCCCTTTTGTGATTGGCATAGCGGGCAGCGTTGCCGTCGGT
AAAAGTACAACGGCTCGCTTACTGAAAGCTCTCTTATCACGTTGGGAGAATCATCCGAAGGTCGAACTGATCACCACAGA
CGGCTTTTTATACCCCAATAAGGTACTGACTGAACGTGGCATTATGCATAAGAAGGGCTTTCCTGAATCTTATGATATTC
GCCGTTTGGTGGAATTTGTTTCTGAGGTTAAAGCTGGCCAGCCCAATGTAACCGCCCCCGTTTATTCACATCTCACTTAT
GATATTACCGATGAAATGAAAGTGGTCGACCGCCCGGATGTGCTGATCATTGAAGGCTTAAATGTACTGCAAAGTGGTAT
GGACTACCCTCATGACCCACACCGCGTATTTATCTCTGATTTCCTGGATTTTTCGATTTATGTCGATGCCGATAGTCAAC
TGATAGAAAAGTGGTATATCGAGCGCTTTATGAAATTTCGCCAGGGTGCATTTAAAAAGCCCGGCTCCTATTTCAGCCAC
TACACTGCACTCACTGAAGCCCAAGCTGAACAGAAAGCGCGTTCCATTTGGGAAACCATCAACGGTAAAAATCTGGTTGA
GAATATCTTGCCGACCAAAGGTCGTGCACATTTGATTTTACGCAAAGGGCTTAACCATACGGTAGAAGAAGTCCTGCTCC
GTAAATAG

Upstream 100 bases:

>100_bases
TTCACTGCTAGTGGAGAAAATGGTGCCGACTACCGGAATCGAACTGGTGACCTACTGATTACAAGTCAGTTGCTCTACCT
ACTGAGCTAAGTCGGCATAA

Downstream 100 bases:

>100_bases
TGCTCAAGAAAAAGAGGCTGACGCCTCTTTATTTGGCTTTAATTCTGCTCTAGTCGTTTTTACGTAGGGATATCTCACCG
CCAATAAAACTTTTCAACCC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVRILVNDLGGCNPYLEKKLNFQRILLVRCFFSQIRAQSLILASFYFVLSCAYCIFAFLILNRMIEPIMSPYLTFDRQHW
AQLRNSVPMTLSESDLKELQGINDHLSMTEAVEIYLPLARLLNLYVAARQSRNGVLHQFLGNTESAPPFVIGIAGSVAVG
KSTTARLLKALLSRWENHPKVELITTDGFLYPNKVLTERGIMHKKGFPESYDIRRLVEFVSEVKAGQPNVTAPVYSHLTY
DITDEMKVVDRPDVLIIEGLNVLQSGMDYPHDPHRVFISDFLDFSIYVDADSQLIEKWYIERFMKFRQGAFKKPGSYFSH
YTALTEAQAEQKARSIWETINGKNLVENILPTKGRAHLILRKGLNHTVEEVLLRK

Sequences:

>Translated_375_residues
MVRILVNDLGGCNPYLEKKLNFQRILLVRCFFSQIRAQSLILASFYFVLSCAYCIFAFLILNRMIEPIMSPYLTFDRQHW
AQLRNSVPMTLSESDLKELQGINDHLSMTEAVEIYLPLARLLNLYVAARQSRNGVLHQFLGNTESAPPFVIGIAGSVAVG
KSTTARLLKALLSRWENHPKVELITTDGFLYPNKVLTERGIMHKKGFPESYDIRRLVEFVSEVKAGQPNVTAPVYSHLTY
DITDEMKVVDRPDVLIIEGLNVLQSGMDYPHDPHRVFISDFLDFSIYVDADSQLIEKWYIERFMKFRQGAFKKPGSYFSH
YTALTEAQAEQKARSIWETINGKNLVENILPTKGRAHLILRKGLNHTVEEVLLRK
>Mature_375_residues
MVRILVNDLGGCNPYLEKKLNFQRILLVRCFFSQIRAQSLILASFYFVLSCAYCIFAFLILNRMIEPIMSPYLTFDRQHW
AQLRNSVPMTLSESDLKELQGINDHLSMTEAVEIYLPLARLLNLYVAARQSRNGVLHQFLGNTESAPPFVIGIAGSVAVG
KSTTARLLKALLSRWENHPKVELITTDGFLYPNKVLTERGIMHKKGFPESYDIRRLVEFVSEVKAGQPNVTAPVYSHLTY
DITDEMKVVDRPDVLIIEGLNVLQSGMDYPHDPHRVFISDFLDFSIYVDADSQLIEKWYIERFMKFRQGAFKKPGSYFSH
YTALTEAQAEQKARSIWETINGKNLVENILPTKGRAHLILRKGLNHTVEEVLLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=64.3086816720257, Blast_Score=420, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 42959; Mature: 42959

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRILVNDLGGCNPYLEKKLNFQRILLVRCFFSQIRAQSLILASFYFVLSCAYCIFAFLI
CEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRMIEPIMSPYLTFDRQHWAQLRNSVPMTLSESDLKELQGINDHLSMTEAVEIYLPLAR
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLNLYVAARQSRNGVLHQFLGNTESAPPFVIGIAGSVAVGKSTTARLLKALLSRWENHPK
HHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VELITTDGFLYPNKVLTERGIMHKKGFPESYDIRRLVEFVSEVKAGQPNVTAPVYSHLTY
EEEEEECCCCCCCHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHEEE
DITDEMKVVDRPDVLIIEGLNVLQSGMDYPHDPHRVFISDFLDFSIYVDADSQLIEKWYI
CCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEECCHHHHHHHHHH
ERFMKFRQGAFKKPGSYFSHYTALTEAQAEQKARSIWETINGKNLVENILPTKGRAHLIL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHH
RKGLNHTVEEVLLRK
HHCCCHHHHHHHHCC
>Mature Secondary Structure
MVRILVNDLGGCNPYLEKKLNFQRILLVRCFFSQIRAQSLILASFYFVLSCAYCIFAFLI
CEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRMIEPIMSPYLTFDRQHWAQLRNSVPMTLSESDLKELQGINDHLSMTEAVEIYLPLAR
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLNLYVAARQSRNGVLHQFLGNTESAPPFVIGIAGSVAVGKSTTARLLKALLSRWENHPK
HHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VELITTDGFLYPNKVLTERGIMHKKGFPESYDIRRLVEFVSEVKAGQPNVTAPVYSHLTY
EEEEEECCCCCCCHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHEEE
DITDEMKVVDRPDVLIIEGLNVLQSGMDYPHDPHRVFISDFLDFSIYVDADSQLIEKWYI
CCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEECCHHHHHHHHHH
ERFMKFRQGAFKKPGSYFSHYTALTEAQAEQKARSIWETINGKNLVENILPTKGRAHLIL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHH
RKGLNHTVEEVLLRK
HHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]