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The map label for this gene is dinG

Identifier: 226224503

GI number: 226224503

Start: 1960041

End: 1962827

Strand: Reverse

Name: dinG

Synonym: Lm4b_01916

Alternate gene names: 226224503

Gene position: 1962827-1960041 (Counterclockwise)

Preceding gene: 226224504

Following gene: 226224502

Centisome position: 67.39

GC content: 38.39

Gene sequence:

>2787_bases
ATGAAACAGAAACGCTATATAGTCGTCGATTTAGAAACAACAGGAAATCAAGCTTCACGAGAGGACCGAATTATCCAGTT
CGCTGCTTGCTTTGTTGAATCAGGAAAACGTCTGGAAACATACACGACATTTTTAAATCCAGAAAAACCGATTCCTGCGT
TTATTCAAGAATTAACGGGAATCTCCCCAAAAGACGTTAAAAATGCTCCACTGTTTGAAGATGTCGCACCGATTATCGCG
AATTTACTAGAAGATACTATTTTTGTGGCACATAATGTGTCATTTGACTGGACATTTTTAGAACGAGAAATGACGCGTGC
AGGAATTTCTCTTGGCAAAATGAAAAAACTCGATACTGTGGAATTAGCTAGAATTATGTATCCGGGCATCGATAGTTATA
AACTACAAGACTTGTCCGATGAATTTAATCTTGGGCACGATAAACCGCACCGTGCGGATAGTGATGCGGAAGTGACAGCA
GATTTACTACTCCTTCTCTTAGAAAAGCTAGAAAATTTACCACTACCTGTCATTCGTCAAATGACAACGATTTCTGGCAG
TCTAAAAAGCTATTTACCAGAGCTCTTATTTGAAATTGAAATGCGAAAAGAGCGAGAAAACAAGCCACTTGATCCAGCAT
TCGTAGAACATCGTGGACTAGTTATTCGCAAAAAAGAAGTCGAAAAGCCCACCTATAGTAGAGCAGATTTACTTGAATTT
CCTGAAACAGACGAAGCTAAAATGGCACTATTCAAAAAAGCTGGAGCGCCACTTTATGCAAGAAGTGGTCAATTTGAAAT
GATGAATTTGGTTTTCCAAGCGATGAAATCAGGAAAACATGCCTTGATTGAAGCGGGAACAGGGATTGGGAAATCGTTAG
GTTACTTTTTACCAGCTATTTACCAAGCGAAACAAGCTGAATTACCGGTAGTTATTAGTACATACACCAACTTGCTTCAA
GCTCAATTGTTTGAAAAAGATGTGCCACTCTTAACGAAATTAACAGGATTCAAAGTGAAAGCTAGCTTACTAAAAGGGCG
CGATCATTATTTGAATTTGTTTAAATTTGAGCAGTTACTTCAAGAAGTCGATACGCAATATGATGTAGTTGTGACGAAGC
TTAAATTGCTCGTATGGCTGACGGAAACAACGACTGGTGATATTGATGAAGTGAACCTATCTAGCGGCGGGGAGTTATTC
TGGAATCGGATGAAGCACACAGGCTGGTTTTTATCTGAAAAACATGATCCTTGGCTCGCACACGATTTCTATAAATTCAA
CATCAAACAAGCCAAAAATGCAGATTTAGTCATTGTTAATCACGCACTACTTTTAAATGACCATTTTTCGGGAAGAGAAA
CATTGCCTAAGTATGCTTTTGCAGTAATTGATGAAGCCCATCATTTTGCGGATAGTGCTCGTATGCAAGGAAGTTTTGTT
CTGTCTTACCGAAAAATAAAATATTTTTTGAATCAGCTAGGCTCTTTAGAAAAATATTCCCTTCTCACAAGGCTTGCAAT
GGCTTTCCCAGAAGCAGACAGTTTATATGATTTAGATATTGCGGCAATGAAGTTAAGTGATGCGGTGGAAGAGTTTTTCG
GTCTTCTGAAAATGCAGTTAAACTTCGCGCGTAAAAATTTACAAGAAGTTGTCTTAGTAGAAAACAGCGAAAAAGATGCT
TGGAATGACAAGGTTTATTACGCTGCTGAAAAAGTATTACATTTGCTAAAAGAGTCCGAAAAAAATATGGAAACATTGTT
AGAACAGGGGAAACAAGAAGAAAATGAACTAGGTGAGGCAGAGAGCGCCTTTTTGGAAGAAATGTATGCTTTTTTACTTG
ATTGGAAGAATATGGTAAAACAACTGGAGCAAATGTTGCATAAGAAGTCGCCTATTTTGACCATTTATTTACAAGCTGAC
AAAAATCATTCTATTTCTAGCATTCGTCTAAAAGCTGTCTTGATGGAAGTGGAGCCGACACTTGGAAAAGAGTTTTTTGC
TAAAAAAGAAAGTGTCATCATGACTTCGGCAACTTTAACCGTAAAAGGGAAGTTTGATTATTTACGGAAAAGTCTCGGTC
TGGAAGAAGAACAAATTATGGAAAAACGCATTCCTTCACCGTTTGATTATAAAGAAAATGCGCGAGTGATGATTCCAGAT
GATATGCCCCCAATTAAAGACACACCAATTGAGCGATATACCTTGGAACTTGCGAAATATATTCGCCACATAGCAGTGAA
AACGAATGGACGGATGCTCGTTCTTTTCACCGCTTCTGATATGTTACAAAAAACGTATTATCATATGAAAAATGAAAAAT
CATTAGAAGAGTATGTCCTTCTAGCGCAAGGAGTTTCAGCGGGAAGCGCCGCACGACTGACAAAACAATTCCAAATGTTT
GATAAGTCTATTTTGCTTGGTACGACAAGCTTTTGGGAAGGAATTGATATTCCAGGAGAAGACTTGTCATGTCTAGTTAT
TGTGAGATTACCATTCGCTCCGATGGATGACCCTTATACAAAAGCACAAATATCCCTTCGCAAAGAACGCGGGGAGAATG
CTTTCCAAACCTATTCTCTACCTGAAGCTGTACTGCGATTTAAGCAAGGTTTTGGTCGGTTAATTAGAAGAGAATCCGAC
CGCGGAATCGTATTTGTTTTTGATAATCGAGTAGATACGACAAAATTTGGAAAAGCATTTTTAGAGTCAATCCCAAGCGC
GCCAATCTTGAAAGGCAAACAGGCGGATTTATTAGAAGAAGTGAGTGAATTCTTTAAGGAAGGTTAA

Upstream 100 bases:

>100_bases
ATAATCAGTTCGGGGAGCTTGAGTGGATTTCTGCTCAAGCTACTCGTTTGTTTGCATCGTTATTTTTGAATAAAAGCAGT
GAAGGAAAGAGGTGGAGCAG

Downstream 100 bases:

>100_bases
ATTTTTCCTGATATGACTTCAAATCTTAGGCCGCTATTGCTATAATGTATCTATGCGAAAATGAAAATGCATATCGCCGG
AGGAATTCCGGTAATTTAGA

Product: bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 928; Mature: 928

Protein sequence:

>928_residues
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTGISPKDVKNAPLFEDVAPIIA
NLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTVELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTA
DLLLLLLEKLENLPLPVIRQMTTISGSLKSYLPELLFEIEMRKERENKPLDPAFVEHRGLVIRKKEVEKPTYSRADLLEF
PETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAIYQAKQAELPVVISTYTNLLQ
AQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLLQEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELF
WNRMKHTGWFLSEKHDPWLAHDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFV
LSYRKIKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEEFFGLLKMQLNFARKNLQEVVLVENSEKDA
WNDKVYYAAEKVLHLLKESEKNMETLLEQGKQEENELGEAESAFLEEMYAFLLDWKNMVKQLEQMLHKKSPILTIYLQAD
KNHSISSIRLKAVLMEVEPTLGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKRIPSPFDYKENARVMIPD
DMPPIKDTPIERYTLELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVLLAQGVSAGSAARLTKQFQMF
DKSILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYTKAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESD
RGIVFVFDNRVDTTKFGKAFLESIPSAPILKGKQADLLEEVSEFFKEG

Sequences:

>Translated_928_residues
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTGISPKDVKNAPLFEDVAPIIA
NLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTVELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTA
DLLLLLLEKLENLPLPVIRQMTTISGSLKSYLPELLFEIEMRKERENKPLDPAFVEHRGLVIRKKEVEKPTYSRADLLEF
PETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAIYQAKQAELPVVISTYTNLLQ
AQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLLQEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELF
WNRMKHTGWFLSEKHDPWLAHDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFV
LSYRKIKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEEFFGLLKMQLNFARKNLQEVVLVENSEKDA
WNDKVYYAAEKVLHLLKESEKNMETLLEQGKQEENELGEAESAFLEEMYAFLLDWKNMVKQLEQMLHKKSPILTIYLQAD
KNHSISSIRLKAVLMEVEPTLGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKRIPSPFDYKENARVMIPD
DMPPIKDTPIERYTLELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVLLAQGVSAGSAARLTKQFQMF
DKSILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYTKAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESD
RGIVFVFDNRVDTTKFGKAFLESIPSAPILKGKQADLLEEVSEFFKEG
>Mature_928_residues
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTGISPKDVKNAPLFEDVAPIIA
NLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTVELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTA
DLLLLLLEKLENLPLPVIRQMTTISGSLKSYLPELLFEIEMRKERENKPLDPAFVEHRGLVIRKKEVEKPTYSRADLLEF
PETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAIYQAKQAELPVVISTYTNLLQ
AQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLLQEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELF
WNRMKHTGWFLSEKHDPWLAHDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFV
LSYRKIKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEEFFGLLKMQLNFARKNLQEVVLVENSEKDA
WNDKVYYAAEKVLHLLKESEKNMETLLEQGKQEENELGEAESAFLEEMYAFLLDWKNMVKQLEQMLHKKSPILTIYLQAD
KNHSISSIRLKAVLMEVEPTLGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKRIPSPFDYKENARVMIPD
DMPPIKDTPIERYTLELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVLLAQGVSAGSAARLTKQFQMF
DKSILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYTKAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESD
RGIVFVFDNRVDTTKFGKAFLESIPSAPILKGKQADLLEEVSEFFKEG

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788110, Length=657, Percent_Identity=29.3759512937595, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI1787018, Length=701, Percent_Identity=25.3922967189729, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 106157; Mature: 106157

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTG
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHHHHCC
ISPKDVKNAPLFEDVAPIIANLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTV
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCHHHHCCCHHH
ELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTADLLLLLLEKLENLPLPVIRQ
HHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
MTTISGSLKSYLPELLFEIEMRKERENKPLDPAFVEHRGLVIRKKEVEKPTYSRADLLEF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEHHHCCCCCCCCHHHHCC
PETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAI
CCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
YQAKQAELPVVISTYTNLLQAQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLL
HHHHCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
QEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELFWNRMKHTGWFLSEKHDPWLA
HHHCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCEE
HDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFV
CCCEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LSYRKIKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEEFFGLLKMQL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
NFARKNLQEVVLVENSEKDAWNDKVYYAAEKVLHLLKESEKNMETLLEQGKQEENELGEA
HHHHHCHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHH
ESAFLEEMYAFLLDWKNMVKQLEQMLHKKSPILTIYLQADKNHSISSIRLKAVLMEVEPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHEEHHHHHHHCCCH
LGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKRIPSPFDYKENARVMIPD
HCHHHHHCCCCEEEEEEEEEEECCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCC
DMPPIKDTPIERYTLELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVL
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHH
LAQGVSAGSAARLTKQFQMFDKSILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYT
HHCCCCCCHHHHHHHHHHHHHHHHEEECCHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
KAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESDRGIVFVFDNRVDTTKFGKAF
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
LESIPSAPILKGKQADLLEEVSEFFKEG
HHHCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTG
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHHHHCC
ISPKDVKNAPLFEDVAPIIANLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTV
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCHHHHCCCHHH
ELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTADLLLLLLEKLENLPLPVIRQ
HHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
MTTISGSLKSYLPELLFEIEMRKERENKPLDPAFVEHRGLVIRKKEVEKPTYSRADLLEF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEHHHCCCCCCCCHHHHCC
PETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAI
CCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
YQAKQAELPVVISTYTNLLQAQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLL
HHHHCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
QEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELFWNRMKHTGWFLSEKHDPWLA
HHHCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCEE
HDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFV
CCCEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LSYRKIKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEEFFGLLKMQL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
NFARKNLQEVVLVENSEKDAWNDKVYYAAEKVLHLLKESEKNMETLLEQGKQEENELGEA
HHHHHCHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHH
ESAFLEEMYAFLLDWKNMVKQLEQMLHKKSPILTIYLQADKNHSISSIRLKAVLMEVEPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHEEHHHHHHHCCCH
LGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKRIPSPFDYKENARVMIPD
HCHHHHHCCCCEEEEEEEEEEECCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCC
DMPPIKDTPIERYTLELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVL
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHH
LAQGVSAGSAARLTKQFQMFDKSILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYT
HHCCCCCCHHHHHHHHHHHHHHHHEEECCHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
KAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESDRGIVFVFDNRVDTTKFGKAF
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
LESIPSAPILKGKQADLLEEVSEFFKEG
HHHCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]