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The map label for this gene is zraR [H]

Identifier: 225685948

GI number: 225685948

Start: 82035

End: 83525

Strand: Direct

Name: zraR [H]

Synonym: BMEA_B0086

Alternate gene names: 225685948

Gene position: 82035-83525 (Clockwise)

Preceding gene: 225685940

Following gene: 225685949

Centisome position: 6.92

GC content: 59.56

Gene sequence:

>1491_bases
ATGGCAACGCGCATTCTCATAGCGGATGACGATCCGATTCAGCGACGCAATCTCGAAGCAATAGTCATGCGCATGGGTTA
TCGCACGATCCTTGCCGATGGCGGGGTAAGTGCGCTGGGCTTCATAAGCCAGCGCAAGGATATCGTGCTGGTGCTGCTGG
ACCTCACCATGCCGGATATGGACGGCCTCACCGTTTTGTCGCGGATGCGCGCGGCCGGGGTGGCGGTGCCGGTTATCGTG
CTGGTGCATAGCGATGACATGCATCGCGTTGCGCAGGCCATCAGGCTTGGCGCGGCGGATTTCATGATAAAGCCGCTGAT
TTTCGAGCGTGTTCAGGTTTCCGTTGCAAATGTGTTGAAACTCGACGCGCTGACACATGAGATACAGCGTGCCCGTTCTT
CCCCGAGGGTGCATCTTTCGCTTTCGGAAATGGTGGCAAAAAGCCCTGAAATGGAGCGGGTGATGGTTCTGGCGCGCCGC
GCGGCGGCGCTGGATGCCCCGCTTCTGGTCGAAGGCGAGACTGGCAGCGGCAGGCAAACGCTTGCGCGCGCCATTTGCGG
TGGCGGGTCGCGCTGGCGCGGCCCCTTCGTTTCACTCGACTGTCGCGGGCTTACGATGGAAAATGCCGACGATATCCTGT
TCGGCACTGCGAAGTTCTGCCCGGATGATCCGATCGTCAGCGCCGGTAAACTGGCGGAAGCCGATGGCGGCGTCCTGTTT
CTGGATGAAGTCGGCGCATTGCCGCACCACGCGCAGCTTCGGTTATTTACCGCCATGCAGTCGGGCCAGTATGAATCGAA
CGGTTCGCGGGTGACGTCCAATGCCCGCATCATGACTTCCAGCAGCCAGCCGCTGGTCGATTTCGTTCATATGGGGCGTT
TTCATGCCGGGCTTTATCATCTGCTCGGCTCCTTTTCCATCGCAATGCCGCCCTTGCGGGAGCGCGTGGAGGATATTTCC
ATTCTCGTGCACCAGTTTGCGGTGCGCTTTGCCAGCGAGGAGCGGCTGAGCCACATCACCGGCATTGCGCCGCATCTGCT
GGAACGGCTGAAGGCCTATCAGTGGCCCGGCAATGTGCGTGAATTGAAGAATGCTGTTTATCGTGCGGTTCTGCTCTGCG
ACAAAAGCGAACTGACGGTCGAGGATTTTGCGCAGCTTAATCTTGGTGCCGCCGGTTTTGCCGGGGCGCAGGCGATGTGG
CAGAAACCGGCCGCTCCCTTATCGGTCGGGCGCGCGGGCACTGCCTTCAGCGGCATTGATGCCGATGGCGAAGTGCGCAC
CCTTGCTGCTGCCGAGGAAGAAATGATCCGCTTTGCGATTGCACATTACGACGGGCAAATCAGCGAGGTTGCGCGCCGTC
TGGGCATTGGCAGGACCACGCTTTACCGCAAGCTGAAAGAATATGGCATCGATGTGGCGTCGATTTCCGGCAAGGGCAAA
GAGAGCGATCTTGAGAATGAAAGCTGCTCATGGGGCCGCGCGGCCATATAG

Upstream 100 bases:

>100_bases
AGTGGACACTTCGCTCAAATAATGTGCTTGGTATATCAGGAAACCGATATGTTCCTATATATCACGGCGCGGCAACATCA
ACGGTTGATAAAAGCAATTT

Downstream 100 bases:

>100_bases
GCTGGACAATATAAGTCCATGAATTTTATGCGCTTCCCATATTTTGCCTGTTTTTGCTGCCAGGATGTGTCCCAATCGCA
AGTCTGTTAATAAAATCTTT

Product: two component, sigma54 specific, transcriptional regulator, Fis family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MATRILIADDDPIQRRNLEAIVMRMGYRTILADGGVSALGFISQRKDIVLVLLDLTMPDMDGLTVLSRMRAAGVAVPVIV
LVHSDDMHRVAQAIRLGAADFMIKPLIFERVQVSVANVLKLDALTHEIQRARSSPRVHLSLSEMVAKSPEMERVMVLARR
AAALDAPLLVEGETGSGRQTLARAICGGGSRWRGPFVSLDCRGLTMENADDILFGTAKFCPDDPIVSAGKLAEADGGVLF
LDEVGALPHHAQLRLFTAMQSGQYESNGSRVTSNARIMTSSSQPLVDFVHMGRFHAGLYHLLGSFSIAMPPLRERVEDIS
ILVHQFAVRFASEERLSHITGIAPHLLERLKAYQWPGNVRELKNAVYRAVLLCDKSELTVEDFAQLNLGAAGFAGAQAMW
QKPAAPLSVGRAGTAFSGIDADGEVRTLAAAEEEMIRFAIAHYDGQISEVARRLGIGRTTLYRKLKEYGIDVASISGKGK
ESDLENESCSWGRAAI

Sequences:

>Translated_496_residues
MATRILIADDDPIQRRNLEAIVMRMGYRTILADGGVSALGFISQRKDIVLVLLDLTMPDMDGLTVLSRMRAAGVAVPVIV
LVHSDDMHRVAQAIRLGAADFMIKPLIFERVQVSVANVLKLDALTHEIQRARSSPRVHLSLSEMVAKSPEMERVMVLARR
AAALDAPLLVEGETGSGRQTLARAICGGGSRWRGPFVSLDCRGLTMENADDILFGTAKFCPDDPIVSAGKLAEADGGVLF
LDEVGALPHHAQLRLFTAMQSGQYESNGSRVTSNARIMTSSSQPLVDFVHMGRFHAGLYHLLGSFSIAMPPLRERVEDIS
ILVHQFAVRFASEERLSHITGIAPHLLERLKAYQWPGNVRELKNAVYRAVLLCDKSELTVEDFAQLNLGAAGFAGAQAMW
QKPAAPLSVGRAGTAFSGIDADGEVRTLAAAEEEMIRFAIAHYDGQISEVARRLGIGRTTLYRKLKEYGIDVASISGKGK
ESDLENESCSWGRAAI
>Mature_495_residues
ATRILIADDDPIQRRNLEAIVMRMGYRTILADGGVSALGFISQRKDIVLVLLDLTMPDMDGLTVLSRMRAAGVAVPVIVL
VHSDDMHRVAQAIRLGAADFMIKPLIFERVQVSVANVLKLDALTHEIQRARSSPRVHLSLSEMVAKSPEMERVMVLARRA
AALDAPLLVEGETGSGRQTLARAICGGGSRWRGPFVSLDCRGLTMENADDILFGTAKFCPDDPIVSAGKLAEADGGVLFL
DEVGALPHHAQLRLFTAMQSGQYESNGSRVTSNARIMTSSSQPLVDFVHMGRFHAGLYHLLGSFSIAMPPLRERVEDISI
LVHQFAVRFASEERLSHITGIAPHLLERLKAYQWPGNVRELKNAVYRAVLLCDKSELTVEDFAQLNLGAAGFAGAQAMWQ
KPAAPLSVGRAGTAFSGIDADGEVRTLAAAEEEMIRFAIAHYDGQISEVARRLGIGRTTLYRKLKEYGIDVASISGKGKE
SDLENESCSWGRAAI

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=465, Percent_Identity=33.7634408602151, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788550, Length=478, Percent_Identity=30.1255230125523, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=29.4363256784969, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1788905, Length=372, Percent_Identity=28.7634408602151, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1789233, Length=332, Percent_Identity=31.6265060240964, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787583, Length=334, Percent_Identity=30.5389221556886, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87081872, Length=224, Percent_Identity=35.7142857142857, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87082117, Length=351, Percent_Identity=29.9145299145299, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789087, Length=426, Percent_Identity=28.169014084507, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI87082152, Length=347, Percent_Identity=30.2593659942363, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081858, Length=346, Percent_Identity=28.0346820809249, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786524, Length=374, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789828, Length=258, Percent_Identity=29.0697674418605, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787487, Length=110, Percent_Identity=34.5454545454545, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53967; Mature: 53836

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRILIADDDPIQRRNLEAIVMRMGYRTILADGGVSALGFISQRKDIVLVLLDLTMPDM
CCEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEEEEECCCCCC
DGLTVLSRMRAAGVAVPVIVLVHSDDMHRVAQAIRLGAADFMIKPLIFERVQVSVANVLK
CHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LDALTHEIQRARSSPRVHLSLSEMVAKSPEMERVMVLARRAAALDAPLLVEGETGSGRQT
HHHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHH
LARAICGGGSRWRGPFVSLDCRGLTMENADDILFGTAKFCPDDPIVSAGKLAEADGGVLF
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEE
LDEVGALPHHAQLRLFTAMQSGQYESNGSRVTSNARIMTSSSQPLVDFVHMGRFHAGLYH
EECCCCCCCCHHEEEEEHHHCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHH
LLGSFSIAMPPLRERVEDISILVHQFAVRFASEERLSHITGIAPHLLERLKAYQWPGNVR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELKNAVYRAVLLCDKSELTVEDFAQLNLGAAGFAGAQAMWQKPAAPLSVGRAGTAFSGID
HHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
ADGEVRTLAAAEEEMIRFAIAHYDGQISEVARRLGIGRTTLYRKLKEYGIDVASISGKGK
CCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCC
ESDLENESCSWGRAAI
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATRILIADDDPIQRRNLEAIVMRMGYRTILADGGVSALGFISQRKDIVLVLLDLTMPDM
CEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEEEEECCCCCC
DGLTVLSRMRAAGVAVPVIVLVHSDDMHRVAQAIRLGAADFMIKPLIFERVQVSVANVLK
CHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LDALTHEIQRARSSPRVHLSLSEMVAKSPEMERVMVLARRAAALDAPLLVEGETGSGRQT
HHHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHH
LARAICGGGSRWRGPFVSLDCRGLTMENADDILFGTAKFCPDDPIVSAGKLAEADGGVLF
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEE
LDEVGALPHHAQLRLFTAMQSGQYESNGSRVTSNARIMTSSSQPLVDFVHMGRFHAGLYH
EECCCCCCCCHHEEEEEHHHCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHH
LLGSFSIAMPPLRERVEDISILVHQFAVRFASEERLSHITGIAPHLLERLKAYQWPGNVR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELKNAVYRAVLLCDKSELTVEDFAQLNLGAAGFAGAQAMWQKPAAPLSVGRAGTAFSGID
HHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
ADGEVRTLAAAEEEMIRFAIAHYDGQISEVARRLGIGRTTLYRKLKEYGIDVASISGKGK
CCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCC
ESDLENESCSWGRAAI
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]