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The map label for this gene is yyaJ [H]

Identifier: 220904682

GI number: 220904682

Start: 1691787

End: 1693121

Strand: Direct

Name: yyaJ [H]

Synonym: Ddes_1414

Alternate gene names: 220904682

Gene position: 1691787-1693121 (Clockwise)

Preceding gene: 220904680

Following gene: 220904683

Centisome position: 58.88

GC content: 53.33

Gene sequence:

>1335_bases
ATGCCCGGCCAAGAAAAAATCAGCAACAACTACTTCGACGGACTAAAAGTCTGCGGTCGCCATAAAGCAGTGTTCTTCAT
CATAATGGTGGCCTACTTTTGTGAACAAATGGATAACTGGAACTTCGGCTTCATTGCCCCGGCCCTGATGCAGCACTGGG
GGCTGACCATGAAGGATATCGGCACGGTTACCTTCTGGTATTTTGCGGCAATGACCTGCGGCGGATTTGCGGGGGGCTTT
ATTTCTGACATGATCGGCCGCCGCAAAACATTTCTGATCGCCATCACGCTGTTTTCCACAGCCTCCATTATCAATGGACT
TACTGACGATTTTCACGTTTTTGTGGCCTCACGCGCACTCACGGGCTTTGGTGTCTTCTGCCTCATGGTGTGCTCACAAG
CCTATATCGCCGAGATGGCTCCGGCAGAAAGCCGGGGCAAGTGGCAAAACCTTGTGGCAGGCGTGGGTTTTTGTGCGGTA
CCCGTTATCGGCCTGCTCTGCCGGGTTATTATTCCTCTGCATGAAGAGGCCTGGCGCTATATTTTCTACCTGGGCGGCAT
TGGCTACATTGCCCTGTTCATCGCCTGGAAATATCTGGACGAATCACCGCGCTGGCTTGTGAGCCGGGGCCGCATTAAAG
AAGCCGAAGCGGTCATGCTTGACCTCACCCACATGAACATCGACCTTTCTGCGGCAGCCGCCAGGGTCAACACCAGCAAA
CCGCCTATCAAGGAAGTACTGCTGGGCATGATCAGCCAGAAGTACATAAAGCGCACCCTGGTCATTCTGGTGATTGTGCT
CTGCACCAATCCGGCAACATTTGTTGTGACCAACTGGACAGCCACCCTGCTCAAGGCACACGGTTTTTCTCTTGAACAGT
GCCTTATGGCCACTACGCTGATTTCCATCGGCGTTCCCCTTGGCCTCTTTGCTTCCAGCGCCTTTACAGACCTTGGCGGA
CGCAAGATTCCCCTGGTCATCATGCTTGTCTGCATGGCGATTCTTGCGCCCATATTCGGCAACGTCAGCCATTACTGGGT
CGTCGTGTCCGTAGGTGCGCTGCTCACCGCTTTTGTCATGGGCCTGGGATTCACCGTTTTTTCGTACACTGCAGAATCCT
ATCCGACACATCTGCGAAATACCGCGACAGGCTTTCACTCTTCCATCGGACGCCTTGCGGTAGCTTTTTCACAACCTCTC
ATTCCTGTTGTGTATGCAGCATACAGCTTTGACGGCGTGTTCTATATCTTTAGCGCGCTTTGCGTTGTCCCCGCCATTGT
ACTGGCCATATGGGGAGCACGTACGGGCGGCAAGTCCCTTGAGGATATTGCCTAA

Upstream 100 bases:

>100_bases
CCACCAACAAACTATTAATAGCACAACCTCCTTCTCCCGTTGATGTTTTGCAAAAAGACTGAAAAATTCAGGCACAGACA
AGAGCCAAAAGGGGAAATCC

Downstream 100 bases:

>100_bases
AACAATTGCATAAACCTTCCTGAGGCCGCGGCGCGAGCAGATGCGTAAAGCCTGCCCGCGCCGCGCGGCCTTTAACGGTA
AACCGCCAAGGAGTATTGCC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MPGQEKISNNYFDGLKVCGRHKAVFFIIMVAYFCEQMDNWNFGFIAPALMQHWGLTMKDIGTVTFWYFAAMTCGGFAGGF
ISDMIGRRKTFLIAITLFSTASIINGLTDDFHVFVASRALTGFGVFCLMVCSQAYIAEMAPAESRGKWQNLVAGVGFCAV
PVIGLLCRVIIPLHEEAWRYIFYLGGIGYIALFIAWKYLDESPRWLVSRGRIKEAEAVMLDLTHMNIDLSAAAARVNTSK
PPIKEVLLGMISQKYIKRTLVILVIVLCTNPATFVVTNWTATLLKAHGFSLEQCLMATTLISIGVPLGLFASSAFTDLGG
RKIPLVIMLVCMAILAPIFGNVSHYWVVVSVGALLTAFVMGLGFTVFSYTAESYPTHLRNTATGFHSSIGRLAVAFSQPL
IPVVYAAYSFDGVFYIFSALCVVPAIVLAIWGARTGGKSLEDIA

Sequences:

>Translated_444_residues
MPGQEKISNNYFDGLKVCGRHKAVFFIIMVAYFCEQMDNWNFGFIAPALMQHWGLTMKDIGTVTFWYFAAMTCGGFAGGF
ISDMIGRRKTFLIAITLFSTASIINGLTDDFHVFVASRALTGFGVFCLMVCSQAYIAEMAPAESRGKWQNLVAGVGFCAV
PVIGLLCRVIIPLHEEAWRYIFYLGGIGYIALFIAWKYLDESPRWLVSRGRIKEAEAVMLDLTHMNIDLSAAAARVNTSK
PPIKEVLLGMISQKYIKRTLVILVIVLCTNPATFVVTNWTATLLKAHGFSLEQCLMATTLISIGVPLGLFASSAFTDLGG
RKIPLVIMLVCMAILAPIFGNVSHYWVVVSVGALLTAFVMGLGFTVFSYTAESYPTHLRNTATGFHSSIGRLAVAFSQPL
IPVVYAAYSFDGVFYIFSALCVVPAIVLAIWGARTGGKSLEDIA
>Mature_443_residues
PGQEKISNNYFDGLKVCGRHKAVFFIIMVAYFCEQMDNWNFGFIAPALMQHWGLTMKDIGTVTFWYFAAMTCGGFAGGFI
SDMIGRRKTFLIAITLFSTASIINGLTDDFHVFVASRALTGFGVFCLMVCSQAYIAEMAPAESRGKWQNLVAGVGFCAVP
VIGLLCRVIIPLHEEAWRYIFYLGGIGYIALFIAWKYLDESPRWLVSRGRIKEAEAVMLDLTHMNIDLSAAAARVNTSKP
PIKEVLLGMISQKYIKRTLVILVIVLCTNPATFVVTNWTATLLKAHGFSLEQCLMATTLISIGVPLGLFASSAFTDLGGR
KIPLVIMLVCMAILAPIFGNVSHYWVVVSVGALLTAFVMGLGFTVFSYTAESYPTHLRNTATGFHSSIGRLAVAFSQPLI
PVVYAAYSFDGVFYIFSALCVVPAIVLAIWGARTGGKSLEDIA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=461, Percent_Identity=26.8980477223427, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI203098995, Length=164, Percent_Identity=27.4390243902439, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI24497490, Length=370, Percent_Identity=21.8918918918919, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI4507005, Length=427, Percent_Identity=22.4824355971897, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788068, Length=379, Percent_Identity=29.023746701847, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788074, Length=384, Percent_Identity=26.3020833333333, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786229, Length=448, Percent_Identity=21.875, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082159, Length=343, Percent_Identity=25.9475218658892, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789312, Length=346, Percent_Identity=21.9653179190751, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081723, Length=349, Percent_Identity=24.0687679083095, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=438, Percent_Identity=23.0593607305936, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25145172, Length=361, Percent_Identity=24.9307479224377, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319718, Length=382, Percent_Identity=23.8219895287958, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652793, Length=459, Percent_Identity=23.3115468409586, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652795, Length=392, Percent_Identity=23.469387755102, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48583; Mature: 48452

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQEKISNNYFDGLKVCGRHKAVFFIIMVAYFCEQMDNWNFGFIAPALMQHWGLTMKDI
CCCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHH
GTVTFWYFAAMTCGGFAGGFISDMIGRRKTFLIAITLFSTASIINGLTDDFHVFVASRAL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEHHHHHHHHHHHCCCCHHHHHHHHHHH
TGFGVFCLMVCSQAYIAEMAPAESRGKWQNLVAGVGFCAVPVIGLLCRVIIPLHEEAWRY
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYLGGIGYIALFIAWKYLDESPRWLVSRGRIKEAEAVMLDLTHMNIDLSAAAARVNTSK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHEEEEEECCEEHHHHHHHCCCCC
PPIKEVLLGMISQKYIKRTLVILVIVLCTNPATFVVTNWTATLLKAHGFSLEQCLMATTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
ISIGVPLGLFASSAFTDLGGRKIPLVIMLVCMAILAPIFGNVSHYWVVVSVGALLTAFVM
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GLGFTVFSYTAESYPTHLRNTATGFHSSIGRLAVAFSQPLIPVVYAAYSFDGVFYIFSAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHH
CVVPAIVLAIWGARTGGKSLEDIA
HHHHHHHHHHHCCCCCCCCHHHCC
>Mature Secondary Structure 
PGQEKISNNYFDGLKVCGRHKAVFFIIMVAYFCEQMDNWNFGFIAPALMQHWGLTMKDI
CCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHH
GTVTFWYFAAMTCGGFAGGFISDMIGRRKTFLIAITLFSTASIINGLTDDFHVFVASRAL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEHHHHHHHHHHHCCCCHHHHHHHHHHH
TGFGVFCLMVCSQAYIAEMAPAESRGKWQNLVAGVGFCAVPVIGLLCRVIIPLHEEAWRY
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYLGGIGYIALFIAWKYLDESPRWLVSRGRIKEAEAVMLDLTHMNIDLSAAAARVNTSK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHEEEEEECCEEHHHHHHHCCCCC
PPIKEVLLGMISQKYIKRTLVILVIVLCTNPATFVVTNWTATLLKAHGFSLEQCLMATTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
ISIGVPLGLFASSAFTDLGGRKIPLVIMLVCMAILAPIFGNVSHYWVVVSVGALLTAFVM
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GLGFTVFSYTAESYPTHLRNTATGFHSSIGRLAVAFSQPLIPVVYAAYSFDGVFYIFSAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHH
CVVPAIVLAIWGARTGGKSLEDIA
HHHHHHHHHHHCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]