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The map label for this gene is lnt [H]

Identifier: 218708741

GI number: 218708741

Start: 755965

End: 757482

Strand: Reverse

Name: lnt [H]

Synonym: VS_0720

Alternate gene names: 218708741

Gene position: 757482-755965 (Counterclockwise)

Preceding gene: 218708742

Following gene: 218708739

Centisome position: 22.96

GC content: 46.51

Gene sequence:

>1518_bases
ATGACTAAGACCTTTATTCATCGCCTATTACGGCCGCTAGCGGCCGTTTTTGTTGGCGCTATAACCACCCTTTCATTCGC
TCCATACTCTATATGGCCTCTTGCTATTCTCAGCCCAGCTTTGTTGCTGTTACTGATTCATAACCGCTCTCCTAAGAGTG
CGCTTTGGGTTGGCTACGCATGGGGTTTAGGTCAATTCACGACAGGTATCAGCTGGGTATACGTCAGCATTGATGGTTTT
GGCGGCATGCCACTGGCTGCCAACCTATTTTTGATGGCATTGCTTGTTGGCTACCTAGCCGTTTATTCGGGTCTATTTAC
CTGGAGTTTGAACAAGTTCTTCCCTGCTAATAACCTAAGCCGCTTTTTCCTTGCAGCTCCTGCATTGTGGTTAATCAGTG
ATTGGCTACGTGGCTGGGTAATGACGGGCTTCCCTTGGCTTTGGTTAGGCTACAGCCAAATCGATTCGCCACTAGGTTCA
TTTGCACCGATTGGCGGCGTCGAGTTAGTAACTCTAGCGATCATTGTTTCAGCCTCTGCATTCGCTTATGCGATTGTTAA
CAGGGCCTGGAGTATCGCTATCATTCCTGCCGTCGTATTTAGCACCGGTTTTGGTATTCGCAACATCGATTGGGTCACGC
CGAACCCTGAAAAAACTACGTCAGTCGTCTTAATACAAGGCAACGTCGATCAAGACAGTAAATGGCTGCCGAGTCATCGC
TGGCCAACCATGATGAAGTACACCGACCTAAGCAGAGAAAACTGGGACGCCGATATCATCATCTGGCCTGAAGCGGCTAT
TCCAGCATTCGAAGTTGAGATCCCATCTTTCCTACGTAACTTGGATAGCGCAGCGAAAATGAACAACAGTTCGATCATTA
CCGGTGTGCTGAATCAGTCTGAAGATAAGAAATACTACAACAGTGTTCTTTCTCTCGGTGTGAATCCATACGGTGAGTAC
AGCTACGATCCAGACGAACGCTACCATAAACACCACCTGTTACCATTTGGTGAGTTTGTGCCGTTTGAAGATATCTTGCG
TCCATTAGCACCTTTCTTTAACTTGCCAATGTCATCATTTAGCCGTGGCGACTTTGTTCAACCAAACATCGTAGCAAATG
GTCGTCATCTAGCACCTGCGTTGTGTTATGAGATCATATTTAATGATCAAGTTAGACAAAACGTAACAGATGAAACTGAC
TTTATTCTAACGCTCTCTAACGATGCGTGGTTTGGTCGTTCGATTGGGCCATTGCAACATATGGAAATTGCACAGATGCG
CGCTCTAGAGCTTGGTAAGCCGCTTATTCGCTCTACCAACAATGGTGTGACGGCTGTTACCGATTATAAAGGCAACATCA
TCAAACAAGTGCCTCAGTTTGAAACGGCCGTATTAAAAGCTGAACTCATTTCAACGGATGGTCAAACGCCTTATCACACA
GTTGGTACTTGGCCACTGTATGTCTGGGCGTTGCTCAGCTTGGTGATGGGTTGGCTAATTAGAAAGCCAAAGAGCTAG

Upstream 100 bases:

>100_bases
ACCGTCGTGTGATTCAGCTACAGGTAACGATACCTGACGAACAACCTCTTCCGACTATCGAAGAATAACAACTTCTCTCT
AAAGAGATGACAGAAATTAG

Downstream 100 bases:

>100_bases
ATTCGAAGAAAAGTGATTCGAGGGTTGACTGGTGGGTCAACCCTTTTTTATTGCCGCAGTTTGAAGTTAATTACATGTTT
ACGGCTTAAGTGCTTTGCGG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTKTFIHRLLRPLAAVFVGAITTLSFAPYSIWPLAILSPALLLLLIHNRSPKSALWVGYAWGLGQFTTGISWVYVSIDGF
GGMPLAANLFLMALLVGYLAVYSGLFTWSLNKFFPANNLSRFFLAAPALWLISDWLRGWVMTGFPWLWLGYSQIDSPLGS
FAPIGGVELVTLAIIVSASAFAYAIVNRAWSIAIIPAVVFSTGFGIRNIDWVTPNPEKTTSVVLIQGNVDQDSKWLPSHR
WPTMMKYTDLSRENWDADIIIWPEAAIPAFEVEIPSFLRNLDSAAKMNNSSIITGVLNQSEDKKYYNSVLSLGVNPYGEY
SYDPDERYHKHHLLPFGEFVPFEDILRPLAPFFNLPMSSFSRGDFVQPNIVANGRHLAPALCYEIIFNDQVRQNVTDETD
FILTLSNDAWFGRSIGPLQHMEIAQMRALELGKPLIRSTNNGVTAVTDYKGNIIKQVPQFETAVLKAELISTDGQTPYHT
VGTWPLYVWALLSLVMGWLIRKPKS

Sequences:

>Translated_505_residues
MTKTFIHRLLRPLAAVFVGAITTLSFAPYSIWPLAILSPALLLLLIHNRSPKSALWVGYAWGLGQFTTGISWVYVSIDGF
GGMPLAANLFLMALLVGYLAVYSGLFTWSLNKFFPANNLSRFFLAAPALWLISDWLRGWVMTGFPWLWLGYSQIDSPLGS
FAPIGGVELVTLAIIVSASAFAYAIVNRAWSIAIIPAVVFSTGFGIRNIDWVTPNPEKTTSVVLIQGNVDQDSKWLPSHR
WPTMMKYTDLSRENWDADIIIWPEAAIPAFEVEIPSFLRNLDSAAKMNNSSIITGVLNQSEDKKYYNSVLSLGVNPYGEY
SYDPDERYHKHHLLPFGEFVPFEDILRPLAPFFNLPMSSFSRGDFVQPNIVANGRHLAPALCYEIIFNDQVRQNVTDETD
FILTLSNDAWFGRSIGPLQHMEIAQMRALELGKPLIRSTNNGVTAVTDYKGNIIKQVPQFETAVLKAELISTDGQTPYHT
VGTWPLYVWALLSLVMGWLIRKPKS
>Mature_504_residues
TKTFIHRLLRPLAAVFVGAITTLSFAPYSIWPLAILSPALLLLLIHNRSPKSALWVGYAWGLGQFTTGISWVYVSIDGFG
GMPLAANLFLMALLVGYLAVYSGLFTWSLNKFFPANNLSRFFLAAPALWLISDWLRGWVMTGFPWLWLGYSQIDSPLGSF
APIGGVELVTLAIIVSASAFAYAIVNRAWSIAIIPAVVFSTGFGIRNIDWVTPNPEKTTSVVLIQGNVDQDSKWLPSHRW
PTMMKYTDLSRENWDADIIIWPEAAIPAFEVEIPSFLRNLDSAAKMNNSSIITGVLNQSEDKKYYNSVLSLGVNPYGEYS
YDPDERYHKHHLLPFGEFVPFEDILRPLAPFFNLPMSSFSRGDFVQPNIVANGRHLAPALCYEIIFNDQVRQNVTDETDF
ILTLSNDAWFGRSIGPLQHMEIAQMRALELGKPLIRSTNNGVTAVTDYKGNIIKQVPQFETAVLKAELISTDGQTPYHTV
GTWPLYVWALLSLVMGWLIRKPKS

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=487, Percent_Identity=47.6386036960986, Blast_Score=466, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56520; Mature: 56389

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTFIHRLLRPLAAVFVGAITTLSFAPYSIWPLAILSPALLLLLIHNRSPKSALWVGYA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
WGLGQFTTGISWVYVSIDGFGGMPLAANLFLMALLVGYLAVYSGLFTWSLNKFFPANNLS
CCCHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCH
RFFLAAPALWLISDWLRGWVMTGFPWLWLGYSQIDSPLGSFAPIGGVELVTLAIIVSASA
HHHHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
FAYAIVNRAWSIAIIPAVVFSTGFGIRNIDWVTPNPEKTTSVVLIQGNVDQDSKWLPSHR
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
WPTMMKYTDLSRENWDADIIIWPEAAIPAFEVEIPSFLRNLDSAAKMNNSSIITGVLNQS
CCCHHHECCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCC
EDKKYYNSVLSLGVNPYGEYSYDPDERYHKHHLLPFGEFVPFEDILRPLAPFFNLPMSSF
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
SRGDFVQPNIVANGRHLAPALCYEIIFNDQVRQNVTDETDFILTLSNDAWFGRSIGPLQH
CCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIAQMRALELGKPLIRSTNNGVTAVTDYKGNIIKQVPQFETAVLKAELISTDGQTPYHT
HHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCCCCEE
VGTWPLYVWALLSLVMGWLIRKPKS
CCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKTFIHRLLRPLAAVFVGAITTLSFAPYSIWPLAILSPALLLLLIHNRSPKSALWVGYA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
WGLGQFTTGISWVYVSIDGFGGMPLAANLFLMALLVGYLAVYSGLFTWSLNKFFPANNLS
CCCHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCH
RFFLAAPALWLISDWLRGWVMTGFPWLWLGYSQIDSPLGSFAPIGGVELVTLAIIVSASA
HHHHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
FAYAIVNRAWSIAIIPAVVFSTGFGIRNIDWVTPNPEKTTSVVLIQGNVDQDSKWLPSHR
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
WPTMMKYTDLSRENWDADIIIWPEAAIPAFEVEIPSFLRNLDSAAKMNNSSIITGVLNQS
CCCHHHECCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCC
EDKKYYNSVLSLGVNPYGEYSYDPDERYHKHHLLPFGEFVPFEDILRPLAPFFNLPMSSF
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
SRGDFVQPNIVANGRHLAPALCYEIIFNDQVRQNVTDETDFILTLSNDAWFGRSIGPLQH
CCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIAQMRALELGKPLIRSTNNGVTAVTDYKGNIIKQVPQFETAVLKAELISTDGQTPYHT
HHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCCCCEE
VGTWPLYVWALLSLVMGWLIRKPKS
CCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]