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The map label for this gene is corC [H]

Identifier: 218708742

GI number: 218708742

Start: 757515

End: 758405

Strand: Reverse

Name: corC [H]

Synonym: VS_0721

Alternate gene names: 218708742

Gene position: 758405-757515 (Counterclockwise)

Preceding gene: 218708743

Following gene: 218708741

Centisome position: 22.99

GC content: 44.56

Gene sequence:

>891_bases
ATGAACGAAGGTAACCCCCCCACTTCTGAGGGAAGTAAAAAATCTGAAGGTCCGAGTAGAAAGTCCTTCTTTGAACGCCT
AGGCCAACTATTTCAAGGTGAAGTAAAAGATCGCCAAGAGCTCGTAGATGTAATCCGCGACTCAGAAATTAATGACCTCA
TTGACCACGACACGCGCGACATGCTCGAGGGTGTAATGGAAATTTCAGAGATGCGAGTACGCGATATCATGCTGCCTCGC
TCTCAAATGGTTACAGTTGAACGCACCGATGATTTAGATACATTGATTGCGCTTATTACTGATGCTCAACACTCTCGCTA
CCCAGTGATCAGTGAAGATAAAGACCATGTTGAAGGCATTCTATTAGCGAAGGACCTACTTAAGTATTTGGGTTCAGAAA
GTGCCCCATTTGATATCGAACAAGTGATTCGCCCTGTCGTGGTTGTTCCTGAAAGTAAGCGTGTTGATCGCCTACTCAAA
GAGTTCCAAGAAGAGCGCTACCACATGTCTATCGTTGTCGATGAGTTTGGCGGAGTTTCTGGCCTGGTAACCATTGAAGA
TATCCTCGAAGAAATCGTTGGTGAAATTGAAGACGAGTTCGACGATGAAGAAGAGCTAGATATTCGTAAGCTGAGTAAGC
ATACCTTCTCTGTAAAAGCTTTAACCACTATTGAAGAGTTCAACGATACGTTTAACACTGCCTTTAGTGACGATGAAGTG
GATACCGTAGGCGGTATGGTGATGACGGCACTCGGTCACCTGCCAGTTCGTGGCGAAATTGTAGAAATCGAAAACTACCA
TTTCAAAATTACGTCTGCAGATAACCGTCGTGTGATTCAGCTACAGGTAACGATACCTGACGAACAACCTCTTCCGACTA
TCGAAGAATAA

Upstream 100 bases:

>100_bases
TTGCAGAGAAACAATAACTCATCGACCCTGTGATTTTCGCAGGAATCTGAGTTGTAACGTGTGCTATCACACTTCTGATA
GCGTTATTTTTTGAGAAATC

Downstream 100 bases:

>100_bases
CAACTTCTCTCTAAAGAGATGACAGAAATTAGATGACTAAGACCTTTATTCATCGCCTATTACGGCCGCTAGCGGCCGTT
TTTGTTGGCGCTATAACCAC

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNEGNPPTSEGSKKSEGPSRKSFFERLGQLFQGEVKDRQELVDVIRDSEINDLIDHDTRDMLEGVMEISEMRVRDIMLPR
SQMVTVERTDDLDTLIALITDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSESAPFDIEQVIRPVVVVPESKRVDRLLK
EFQEERYHMSIVVDEFGGVSGLVTIEDILEEIVGEIEDEFDDEEELDIRKLSKHTFSVKALTTIEEFNDTFNTAFSDDEV
DTVGGMVMTALGHLPVRGEIVEIENYHFKITSADNRRVIQLQVTIPDEQPLPTIEE

Sequences:

>Translated_296_residues
MNEGNPPTSEGSKKSEGPSRKSFFERLGQLFQGEVKDRQELVDVIRDSEINDLIDHDTRDMLEGVMEISEMRVRDIMLPR
SQMVTVERTDDLDTLIALITDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSESAPFDIEQVIRPVVVVPESKRVDRLLK
EFQEERYHMSIVVDEFGGVSGLVTIEDILEEIVGEIEDEFDDEEELDIRKLSKHTFSVKALTTIEEFNDTFNTAFSDDEV
DTVGGMVMTALGHLPVRGEIVEIENYHFKITSADNRRVIQLQVTIPDEQPLPTIEE
>Mature_296_residues
MNEGNPPTSEGSKKSEGPSRKSFFERLGQLFQGEVKDRQELVDVIRDSEINDLIDHDTRDMLEGVMEISEMRVRDIMLPR
SQMVTVERTDDLDTLIALITDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSESAPFDIEQVIRPVVVVPESKRVDRLLK
EFQEERYHMSIVVDEFGGVSGLVTIEDILEEIVGEIEDEFDDEEELDIRKLSKHTFSVKALTTIEEFNDTFNTAFSDDEV
DTVGGMVMTALGHLPVRGEIVEIENYHFKITSADNRRVIQLQVTIPDEQPLPTIEE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=219, Percent_Identity=35.1598173515982, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI40068055, Length=183, Percent_Identity=28.9617486338798, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40068053, Length=183, Percent_Identity=28.9617486338798, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI94681046, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786879, Length=279, Percent_Identity=62.0071684587814, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI145693175, Length=249, Percent_Identity=28.1124497991968, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082033, Length=270, Percent_Identity=25.1851851851852, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790664, Length=238, Percent_Identity=25.6302521008403, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33720; Mature: 33720

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEGNPPTSEGSKKSEGPSRKSFFERLGQLFQGEVKDRQELVDVIRDSEINDLIDHDTRD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCHHH
MLEGVMEISEMRVRDIMLPRSQMVTVERTDDLDTLIALITDAQHSRYPVISEDKDHVEGI
HHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LLAKDLLKYLGSESAPFDIEQVIRPVVVVPESKRVDRLLKEFQEERYHMSIVVDEFGGVS
HHHHHHHHHHCCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCC
GLVTIEDILEEIVGEIEDEFDDEEELDIRKLSKHTFSVKALTTIEEFNDTFNTAFSDDEV
CEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCCH
DTVGGMVMTALGHLPVRGEIVEIENYHFKITSADNRRVIQLQVTIPDEQPLPTIEE
HHHHHHHHHHHCCCCCCCEEEEEECEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNEGNPPTSEGSKKSEGPSRKSFFERLGQLFQGEVKDRQELVDVIRDSEINDLIDHDTRD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCHHH
MLEGVMEISEMRVRDIMLPRSQMVTVERTDDLDTLIALITDAQHSRYPVISEDKDHVEGI
HHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LLAKDLLKYLGSESAPFDIEQVIRPVVVVPESKRVDRLLKEFQEERYHMSIVVDEFGGVS
HHHHHHHHHHCCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCC
GLVTIEDILEEIVGEIEDEFDDEEELDIRKLSKHTFSVKALTTIEEFNDTFNTAFSDDEV
CEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCCH
DTVGGMVMTALGHLPVRGEIVEIENYHFKITSADNRRVIQLQVTIPDEQPLPTIEE
HHHHHHHHHHHCCCCCCCEEEEEECEEEEEECCCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]