BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence.
Accession	NC_011370
Length	308,747

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The map label for this gene is gabD [H]

Identifier: 209552187

GI number: 209552187

Start: 296615

End: 297316

Strand: Reverse

Name: gabD [H]

Synonym: Rleg2_6345

Alternate gene names: 209552187

Gene position: 297316-296615 (Counterclockwise)

Preceding gene: 209552188

Following gene: 209552186

Centisome position: 96.3

GC content: 60.4

Gene sequence:

>702_bases
ATGAACGATTTTGCAAACGCGGCCGACTTCGGCGCGGCCACACTCGGTCAGAAGCTTCGCGAACCTTCTCTTTTCATCGA
ACAAGCCTTCCTGCGAGGTCAATGGGCAGACGCGGACAGCGGAGAGACAATTAGTGTCTTCGATCCGGCTACGGGGCTAA
GAATAGGGACTGTGCCCGCCATGGGCGCAGCCGAGGCGTCTCGGGTTATCGAGAAGGCTTATGCCGCATTCCGTGCCTGG
GCCAGCGAGCCCGCTTTGAACCGCGCTCAGGTCATGGAGAAGTGGTTCGACCTCGTCACCGAGCATGCCGAAGACCTCGC
CACGATCATAACGGTGGAGCAAGGCAAGCCCATCGCCGATCCTACCATCCTTACCGGGGCGCCATCGTCGATGCTGGTTG
CTCGGGAAGAAACGTTCGGTCCGGTGGCTCCGCTGTTCCGTTTCACGCACATCGACGAGGCAATCAGGTTCGCCAACGAT
ACCCCGTTCGGGCTCGCCGCATACGCGTTCTCAGAAAGCATGCATCGAACACTCCACGTCGGAGAGCGGCTCGAATTCGG
GATGATAGGGCTCAACAGCGGGAGCGTTTCGTCGGAAGTCGCGCCGTTCGGTGGAATGAAAGAGTCCGGGATCGGCCGCG
AAGGCGCAGGGCACGGGATGGACGAGTACCTGGACTCAAGACGATGCACATCGGCGGGATGA

Upstream 100 bases:

>100_bases
CCCTCTGTTGCAGCGAAGAAGACATCGACACAATCATTCGCCGATTCCGATCCGTGCTGGACGAGCTCCTCGAGGTTAGA
GAGATTCGGATGGCAGCAGC

Downstream 100 bases:

>100_bases
ACCGGCCCTTGTAGCGGACAAATGAGCGGCGGATCCGATCCAAACCCGCCGCTCGCAATGCTCAATTCGAGCGGTTGAAA
ATCATGGGACTTCGCAATGC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: SSDH [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNDFANAADFGAATLGQKLREPSLFIEQAFLRGQWADADSGETISVFDPATGLRIGTVPAMGAAEASRVIEKAYAAFRAW
ASEPALNRAQVMEKWFDLVTEHAEDLATIITVEQGKPIADPTILTGAPSSMLVAREETFGPVAPLFRFTHIDEAIRFAND
TPFGLAAYAFSESMHRTLHVGERLEFGMIGLNSGSVSSEVAPFGGMKESGIGREGAGHGMDEYLDSRRCTSAG

Sequences:

>Translated_233_residues
MNDFANAADFGAATLGQKLREPSLFIEQAFLRGQWADADSGETISVFDPATGLRIGTVPAMGAAEASRVIEKAYAAFRAW
ASEPALNRAQVMEKWFDLVTEHAEDLATIITVEQGKPIADPTILTGAPSSMLVAREETFGPVAPLFRFTHIDEAIRFAND
TPFGLAAYAFSESMHRTLHVGERLEFGMIGLNSGSVSSEVAPFGGMKESGIGREGAGHGMDEYLDSRRCTSAG
>Mature_233_residues
MNDFANAADFGAATLGQKLREPSLFIEQAFLRGQWADADSGETISVFDPATGLRIGTVPAMGAAEASRVIEKAYAAFRAW
ASEPALNRAQVMEKWFDLVTEHAEDLATIITVEQGKPIADPTILTGAPSSMLVAREETFGPVAPLFRFTHIDEAIRFAND
TPFGLAAYAFSESMHRTLHVGERLEFGMIGLNSGSVSSEVAPFGGMKESGIGREGAGHGMDEYLDSRRCTSAG

Specific function: Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=154, Percent_Identity=40.9090909090909, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI25777721, Length=154, Percent_Identity=40.9090909090909, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI25777730, Length=110, Percent_Identity=38.1818181818182, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI153266822, Length=110, Percent_Identity=37.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI238814322, Length=150, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI25777726, Length=111, Percent_Identity=36.036036036036, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI25777724, Length=111, Percent_Identity=36.036036036036, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI21361176, Length=110, Percent_Identity=35.4545454545455, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI25777728, Length=111, Percent_Identity=36.036036036036, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI21614513, Length=113, Percent_Identity=35.3982300884956, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI25777732, Length=110, Percent_Identity=33.6363636363636, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI12007648, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI25952152, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI301500698, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI115387104, Length=150, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI73695881, Length=114, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI73695879, Length=114, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI11095441, Length=93, Percent_Identity=36.5591397849462, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789015, Length=115, Percent_Identity=51.304347826087, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87081896, Length=107, Percent_Identity=34.5794392523364, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786504, Length=103, Percent_Identity=39.8058252427184, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787558, Length=103, Percent_Identity=33.9805825242718, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081926, Length=105, Percent_Identity=36.1904761904762, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787684, Length=107, Percent_Identity=31.7757009345794, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787715, Length=108, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082295, Length=108, Percent_Identity=36.1111111111111, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534119, Length=106, Percent_Identity=42.4528301886792, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144435, Length=110, Percent_Identity=37.2727272727273, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI32564736, Length=110, Percent_Identity=37.2727272727273, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562198, Length=151, Percent_Identity=33.112582781457, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25143874, Length=103, Percent_Identity=42.7184466019417, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25143876, Length=103, Percent_Identity=42.7184466019417, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI133930964, Length=112, Percent_Identity=37.5, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=107, Percent_Identity=34.5794392523364, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995606, Length=97, Percent_Identity=39.1752577319588, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=111, Percent_Identity=47.7477477477478, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323822, Length=107, Percent_Identity=37.3831775700935, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323821, Length=107, Percent_Identity=37.3831775700935, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320917, Length=107, Percent_Identity=31.7757009345794, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324950, Length=107, Percent_Identity=33.6448598130841, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325196, Length=94, Percent_Identity=35.1063829787234, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281362580, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI62472918, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI62472926, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI62472936, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI21356737, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24650465, Length=112, Percent_Identity=34.8214285714286, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129399, Length=149, Percent_Identity=32.8859060402685, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24585660, Length=112, Percent_Identity=33.9285714285714, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24638876, Length=93, Percent_Identity=38.7096774193548, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24638878, Length=93, Percent_Identity=38.7096774193548, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010102 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.79 [H]

Molecular weight: Translated: 24979; Mature: 24979

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFANAADFGAATLGQKLREPSLFIEQAFLRGQWADADSGETISVFDPATGLRIGTVPA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCC
MGAAEASRVIEKAYAAFRAWASEPALNRAQVMEKWFDLVTEHAEDLATIITVEQGKPIAD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
PTILTGAPSSMLVAREETFGPVAPLFRFTHIDEAIRFANDTPFGLAAYAFSESMHRTLHV
CEEECCCCCHHEEECHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
GERLEFGMIGLNSGSVSSEVAPFGGMKESGIGREGAGHGMDEYLDSRRCTSAG
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDFANAADFGAATLGQKLREPSLFIEQAFLRGQWADADSGETISVFDPATGLRIGTVPA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCC
MGAAEASRVIEKAYAAFRAWASEPALNRAQVMEKWFDLVTEHAEDLATIITVEQGKPIAD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
PTILTGAPSSMLVAREETFGPVAPLFRFTHIDEAIRFANDTPFGLAAYAFSESMHRTLHV
CEEECCCCCHHEEECHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
GERLEFGMIGLNSGSVSSEVAPFGGMKESGIGREGAGHGMDEYLDSRRCTSAG
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]