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The map label for this gene is ygjG [C]

Identifier: 209552188

GI number: 209552188

Start: 297313

End: 298689

Strand: Reverse

Name: ygjG [C]

Synonym: Rleg2_6346

Alternate gene names: 209552188

Gene position: 298689-297313 (Counterclockwise)

Preceding gene: 209552189

Following gene: 209552187

Centisome position: 96.74

GC content: 57.59

Gene sequence:

>1377_bases
ATGCTTGATGATCTCGTTGCGTTGGATAAGCGTCATCTGATCCACCCGGTAGTTTCCTGGCGTGGGCATGAGGCGCGCGG
GGTTCGTATTCTAACTTCGGGGAAGGGGGCGTACGTCACCGATGCCGCGGGAGCGACACTTATCGATGCATTTTCAGGCT
TATGGTGTGTGAACGCCGGGTATGGGCAAGCAAGCATCGTGGATGCCGTGCAGCGCCAGCTGACAGAAATTCCCTATGCC
ACGAACTACTTCCACTACGGCAACGAGCCGGCGATCAGGCTTGCAAAGCGGTTATCTGAATTAGCTCCCGGCAATCTTAA
TAGGGTGTTCTTCACATTGGGCGGGTCCGACGCGATCGACACCGCAATCCGCGTAATCCGATACTATTTCAATGTTACGG
GGCGGCCGAAAAAGAAGCACATGATCGCGTTTCAGCGTGGTTTCCACGGATCCTCCAGCCTCGGATCCGGCCTCACCGCA
CTAAAAAACTTTCATGATGATTTCGACTCTCCTACACCTTTGCAACATCACATTGCGTCGCCGTATCCCTACCGAAATCC
CGTTGGGCAAGATCCGGAACACATCATCGCCGTTTCGGTCCAGGCACTTAAAGACAAGGTGGCGGAGATCGGGGGCGAGA
ATGTCGCCGCTTTGTTTGCAGAGCCCGTCCAGGGATCTGGTGGCGTGCTCGTGCCGCCCGACGGCTGGTTTAAGGCAATG
CGGGATGCTGCGCGGGACCTTGACATCCTGTTCCTTGCCGACGAAGTCATCACCGGCTTCGGCAGAACGGGACCGATGTT
CGGTAGCGAATACGATGGAGTGGTCCCGGACCTCATGACGCTGGCGAAGGGTCTTACCTCCGCATACCAGCCGATGGGCG
CGCTGATGGTGAGCGACGAGATGTATGCCGCAATCGCGGACGGTAGCCCGTCGGATCGTGCGATTGGCCATGGCTTCACA
TATTCCGGTCATCCTGCAAGCGCGGCAGCTGGCTTCGAGGCAATCCGTCTTTACACAGAGGGAGGGCTTCTGGCCAACGG
TCAGAAGATCGCTCCCCGGTTCGCCCAGGGTTTGACGGGCCTGTTGGATCACCCTCTTGTCGGTGACGTACGCGTTCGCG
GTCTCCTCGCGGCCGTCGAACTTGTCACGGACAAGAAAGAGAGGACCAAACCGCACGCCAACCTCCAAATCAGCCAACAT
CTGGCCCGTCTCTCCTATGAAAAGCGCGTGATCTTCCGTGCATTCTCCGACGACATGGCGGGGTTTGCGCCACCCCTCTG
TTGCAGCGAAGAAGACATCGACACAATCATTCGCCGATTCCGATCCGTGCTGGACGAGCTCCTCGAGGTTAGAGAGATTC
GGATGGCAGCAGCATGA

Upstream 100 bases:

>100_bases
GTCGGATCGCGGCCACCAGCCGGGGCGCTTCAGTGTTGACAACATCGGAAAACTTCATTTACACATTACAACTGTACTAC
AGTTAAAATGGTAAAAATCG

Downstream 100 bases:

>100_bases
ACGATTTTGCAAACGCGGCCGACTTCGGCGCGGCCACACTCGGTCAGAAGCTTCGCGAACCTTCTCTTTTCATCGAACAA
GCCTTCCTGCGAGGTCAATG

Product: aminotransferase class-III

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLDDLVALDKRHLIHPVVSWRGHEARGVRILTSGKGAYVTDAAGATLIDAFSGLWCVNAGYGQASIVDAVQRQLTEIPYA
TNYFHYGNEPAIRLAKRLSELAPGNLNRVFFTLGGSDAIDTAIRVIRYYFNVTGRPKKKHMIAFQRGFHGSSSLGSGLTA
LKNFHDDFDSPTPLQHHIASPYPYRNPVGQDPEHIIAVSVQALKDKVAEIGGENVAALFAEPVQGSGGVLVPPDGWFKAM
RDAARDLDILFLADEVITGFGRTGPMFGSEYDGVVPDLMTLAKGLTSAYQPMGALMVSDEMYAAIADGSPSDRAIGHGFT
YSGHPASAAAGFEAIRLYTEGGLLANGQKIAPRFAQGLTGLLDHPLVGDVRVRGLLAAVELVTDKKERTKPHANLQISQH
LARLSYEKRVIFRAFSDDMAGFAPPLCCSEEDIDTIIRRFRSVLDELLEVREIRMAAA

Sequences:

>Translated_458_residues
MLDDLVALDKRHLIHPVVSWRGHEARGVRILTSGKGAYVTDAAGATLIDAFSGLWCVNAGYGQASIVDAVQRQLTEIPYA
TNYFHYGNEPAIRLAKRLSELAPGNLNRVFFTLGGSDAIDTAIRVIRYYFNVTGRPKKKHMIAFQRGFHGSSSLGSGLTA
LKNFHDDFDSPTPLQHHIASPYPYRNPVGQDPEHIIAVSVQALKDKVAEIGGENVAALFAEPVQGSGGVLVPPDGWFKAM
RDAARDLDILFLADEVITGFGRTGPMFGSEYDGVVPDLMTLAKGLTSAYQPMGALMVSDEMYAAIADGSPSDRAIGHGFT
YSGHPASAAAGFEAIRLYTEGGLLANGQKIAPRFAQGLTGLLDHPLVGDVRVRGLLAAVELVTDKKERTKPHANLQISQH
LARLSYEKRVIFRAFSDDMAGFAPPLCCSEEDIDTIIRRFRSVLDELLEVREIRMAAA
>Mature_458_residues
MLDDLVALDKRHLIHPVVSWRGHEARGVRILTSGKGAYVTDAAGATLIDAFSGLWCVNAGYGQASIVDAVQRQLTEIPYA
TNYFHYGNEPAIRLAKRLSELAPGNLNRVFFTLGGSDAIDTAIRVIRYYFNVTGRPKKKHMIAFQRGFHGSSSLGSGLTA
LKNFHDDFDSPTPLQHHIASPYPYRNPVGQDPEHIIAVSVQALKDKVAEIGGENVAALFAEPVQGSGGVLVPPDGWFKAM
RDAARDLDILFLADEVITGFGRTGPMFGSEYDGVVPDLMTLAKGLTSAYQPMGALMVSDEMYAAIADGSPSDRAIGHGFT
YSGHPASAAAGFEAIRLYTEGGLLANGQKIAPRFAQGLTGLLDHPLVGDVRVRGLLAAVELVTDKKERTKPHANLQISQH
LARLSYEKRVIFRAFSDDMAGFAPPLCCSEEDIDTIIRRFRSVLDELLEVREIRMAAA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=476, Percent_Identity=27.1008403361345, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=27.8422273781903, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=28.0742459396752, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=409, Percent_Identity=28.361858190709, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=27.1264367816092, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4557809, Length=405, Percent_Identity=27.1604938271605, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI284507298, Length=321, Percent_Identity=27.7258566978193, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI188536080, Length=452, Percent_Identity=22.3451327433628, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679950, Length=452, Percent_Identity=22.3451327433628, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679946, Length=452, Percent_Identity=22.3451327433628, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI145693181, Length=412, Percent_Identity=28.6407766990291, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789759, Length=412, Percent_Identity=28.1553398058252, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789016, Length=385, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788044, Length=422, Percent_Identity=28.6729857819905, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786991, Length=385, Percent_Identity=27.5324675324675, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787560, Length=370, Percent_Identity=30, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=26.4264264264264, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=28.0373831775701, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=419, Percent_Identity=25.5369928400955, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=26.3403263403263, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=244, Percent_Identity=29.0983606557377, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=434, Percent_Identity=24.6543778801843, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324386, Length=487, Percent_Identity=24.6406570841889, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=376, Percent_Identity=22.8723404255319, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321456, Length=293, Percent_Identity=26.962457337884, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=29.8611111111111, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=29.1375291375291, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=26.4367816091954, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21357415, Length=414, Percent_Identity=27.2946859903382, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281366494, Length=441, Percent_Identity=24.0362811791383, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667139, Length=441, Percent_Identity=24.0362811791383, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667143, Length=441, Percent_Identity=24.0362811791383, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49690; Mature: 49690

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDLVALDKRHLIHPVVSWRGHEARGVRILTSGKGAYVTDAAGATLIDAFSGLWCVNAG
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHCCCEEEECC
YGQASIVDAVQRQLTEIPYATNYFHYGNEPAIRLAKRLSELAPGNLNRVFFTLGGSDAID
CCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
TAIRVIRYYFNVTGRPKKKHMIAFQRGFHGSSSLGSGLTALKNFHDDFDSPTPLQHHIAS
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCC
PYPYRNPVGQDPEHIIAVSVQALKDKVAEIGGENVAALFAEPVQGSGGVLVPPDGWFKAM
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCHHHHHH
RDAARDLDILFLADEVITGFGRTGPMFGSEYDGVVPDLMTLAKGLTSAYQPMGALMVSDE
HHHHCCCEEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECCC
MYAAIADGSPSDRAIGHGFTYSGHPASAAAGFEAIRLYTEGGLLANGQKIAPRFAQGLTG
CEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCEEECCCHHHHHHHHHHHH
LLDHPLVGDVRVRGLLAAVELVTDKKERTKPHANLQISQHLARLSYEKRVIFRAFSDDMA
HHCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAPPLCCSEEDIDTIIRRFRSVLDELLEVREIRMAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDDLVALDKRHLIHPVVSWRGHEARGVRILTSGKGAYVTDAAGATLIDAFSGLWCVNAG
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHCCCEEEECC
YGQASIVDAVQRQLTEIPYATNYFHYGNEPAIRLAKRLSELAPGNLNRVFFTLGGSDAID
CCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
TAIRVIRYYFNVTGRPKKKHMIAFQRGFHGSSSLGSGLTALKNFHDDFDSPTPLQHHIAS
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCC
PYPYRNPVGQDPEHIIAVSVQALKDKVAEIGGENVAALFAEPVQGSGGVLVPPDGWFKAM
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCHHHHHH
RDAARDLDILFLADEVITGFGRTGPMFGSEYDGVVPDLMTLAKGLTSAYQPMGALMVSDE
HHHHCCCEEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECCC
MYAAIADGSPSDRAIGHGFTYSGHPASAAAGFEAIRLYTEGGLLANGQKIAPRFAQGLTG
CEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCEEECCCHHHHHHHHHHHH
LLDHPLVGDVRVRGLLAAVELVTDKKERTKPHANLQISQHLARLSYEKRVIFRAFSDDMA
HHCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAPPLCCSEEDIDTIIRRFRSVLDELLEVREIRMAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]