| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
Click here to switch to the map view.
The map label for this gene is dnaN [H]
Identifier: 189184479
GI number: 189184479
Start: 1599725
End: 1601023
Strand: Reverse
Name: dnaN [H]
Synonym: OTT_1572
Alternate gene names: 189184479
Gene position: 1601023-1599725 (Counterclockwise)
Preceding gene: 189184480
Following gene: 189184478
Centisome position: 79.69
GC content: 28.48
Gene sequence:
>1299_bases ATGAATACTAAGTATCCAAAGGTTGATCATAATGATCTAGTAATATCTGACTTTAACATCAAGCTTGATACCAAAAATTT TTCCCGCGCTCTCAATTTTTGCATGCCTATACTGGAAAAAAAAAATGTAGATCAAATTTTAAGTAATGTTAAGCTTACTC ATATCAATGATACTGTAGAAAAGCGTTTGGAAATAAGCGCTACTGATGGAGATATTTTTATTTACCAAAAGCTACCAATT AAAATTAGTAAAAATGATATTAGCATAACTCTTCCATTACAGGCATTAAATGAAATAGTGAAAAAAATTCCACATGATGA ATTTACTATCTATTGTAACCAAGATAATAAAATGGTGCAAATTAAAGTAGGTGAATATCTTGAGTTTAATCTAGCAACAT TGCCTATCAATCTTTTTCCAGTAATTGAAGAACTTACTGATGCAGATTTTATTATTCACGTCACTGCTATGCAGTTAGCG CAGATGATTGAATATACTAAATTTGCTATATCTACAGAAGAAACACGATATAATCTCAATGGTATTTATCTACATTCAAA AGACTATAAATCATTAATAGCAGTAGCAACTGACGGGCACCGGCTTGCAAGTGCTAAATGCAACATTGATACTTTTAAAA CCAATATATCTAATAATGATGGCTTTGGTGTTATTTTGCCACGTAAAACTATAACAGAATTATATAAAATTTTTAAAGAA CCATCAATAAATCAATATAACGTCATTATAAAAGTAAAAAGTAATAAAATACAATTTGATTGTCAAAATATTACTATTAT TTCAAAATTAATAGATGGTAACTTTCCAGAATATGAACTGTTTATTCCTGCTAATAACACAAAAAAAATAATTCTTAATT CTAATGATCTTTCTGAATCAATTGAAAGAGTTTCTACTATCGCAGTTGAAAAATCTAAAATAGTTATTTTAGATTTAGAT CATCATGCTATTACAATTAGTGCTTACGGTAATGCTCAATGCAAGGCTAAAGAATTATTACTTCGACACCAGCATAATAA CAAGAATGATCAACATCAATCTTCTAAACAGGAAGTAGAAAAATATGAATATATAGGCGATGATCAACTTACAATAGCAT TTAATGCAAAATACTTGCTTGATGTTTTAAGTGTATGTAATAATATTAAAATTCCTATTGAATTTAAAGACTCTATATCT CCAGCTTTGATTCAATTAGAAGAAAAAAACACTAGCGCCACTTTTATAATAATGCCAGTTAGTGTCCCTACTCAAGAGTT TGTTAGTGCTCCTACTTAA
Upstream 100 bases:
>100_bases TAAAACAGTAGAAGATCTAAGTAAACAGGAGCAAGAATTTGAAGATGAAGTACGTCTATTAATGAGAATACTGCAAAATT AATATGAGTAATGAATAATT
Downstream 100 bases:
>100_bases GAGTAAGATATTTATAATATAGTATTTTTACTATGCTATATTTAGATTGTTTATTTATGGGTTATTTTTTAATAATGCTA ATATTTAGTATTAACTTGTT
Product: DNA polymerase III subunit beta
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 432; Mature: 432
Protein sequence:
>432_residues MNTKYPKVDHNDLVISDFNIKLDTKNFSRALNFCMPILEKKNVDQILSNVKLTHINDTVEKRLEISATDGDIFIYQKLPI KISKNDISITLPLQALNEIVKKIPHDEFTIYCNQDNKMVQIKVGEYLEFNLATLPINLFPVIEELTDADFIIHVTAMQLA QMIEYTKFAISTEETRYNLNGIYLHSKDYKSLIAVATDGHRLASAKCNIDTFKTNISNNDGFGVILPRKTITELYKIFKE PSINQYNVIIKVKSNKIQFDCQNITIISKLIDGNFPEYELFIPANNTKKIILNSNDLSESIERVSTIAVEKSKIVILDLD HHAITISAYGNAQCKAKELLLRHQHNNKNDQHQSSKQEVEKYEYIGDDQLTIAFNAKYLLDVLSVCNNIKIPIEFKDSIS PALIQLEEKNTSATFIIMPVSVPTQEFVSAPT
Sequences:
>Translated_432_residues MNTKYPKVDHNDLVISDFNIKLDTKNFSRALNFCMPILEKKNVDQILSNVKLTHINDTVEKRLEISATDGDIFIYQKLPI KISKNDISITLPLQALNEIVKKIPHDEFTIYCNQDNKMVQIKVGEYLEFNLATLPINLFPVIEELTDADFIIHVTAMQLA QMIEYTKFAISTEETRYNLNGIYLHSKDYKSLIAVATDGHRLASAKCNIDTFKTNISNNDGFGVILPRKTITELYKIFKE PSINQYNVIIKVKSNKIQFDCQNITIISKLIDGNFPEYELFIPANNTKKIILNSNDLSESIERVSTIAVEKSKIVILDLD HHAITISAYGNAQCKAKELLLRHQHNNKNDQHQSSKQEVEKYEYIGDDQLTIAFNAKYLLDVLSVCNNIKIPIEFKDSIS PALIQLEEKNTSATFIIMPVSVPTQEFVSAPT >Mature_432_residues MNTKYPKVDHNDLVISDFNIKLDTKNFSRALNFCMPILEKKNVDQILSNVKLTHINDTVEKRLEISATDGDIFIYQKLPI KISKNDISITLPLQALNEIVKKIPHDEFTIYCNQDNKMVQIKVGEYLEFNLATLPINLFPVIEELTDADFIIHVTAMQLA QMIEYTKFAISTEETRYNLNGIYLHSKDYKSLIAVATDGHRLASAKCNIDTFKTNISNNDGFGVILPRKTITELYKIFKE PSINQYNVIIKVKSNKIQFDCQNITIISKLIDGNFPEYELFIPANNTKKIILNSNDLSESIERVSTIAVEKSKIVILDLD HHAITISAYGNAQCKAKELLLRHQHNNKNDQHQSSKQEVEKYEYIGDDQLTIAFNAKYLLDVLSVCNNIKIPIEFKDSIS PALIQLEEKNTSATFIIMPVSVPTQEFVSAPT
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped
COG id: COG0592
COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1790136, Length=381, Percent_Identity=25.7217847769029, Blast_Score=122, Evalue=6e-29,
Paralogues:
None
Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001001 - InterPro: IPR022635 - InterPro: IPR022637 - InterPro: IPR022634 [H]
Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 49193; Mature: 49193
Theoretical pI: Translated: 6.30; Mature: 6.30
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTKYPKVDHNDLVISDFNIKLDTKNFSRALNFCMPILEKKNVDQILSNVKLTHINDTVE CCCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECHHHH KRLEISATDGDIFIYQKLPIKISKNDISITLPLQALNEIVKKIPHDEFTIYCNQDNKMVQ CCEEEEECCCCEEEEEEECEEEECCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCCEEE IKVGEYLEFNLATLPINLFPVIEELTDADFIIHVTAMQLAQMIEYTKFAISTEETRYNLN EEECCEEEEEEEEECEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEEECCCCEEEEE GIYLHSKDYKSLIAVATDGHRLASAKCNIDTFKTNISNNDGFGVILPRKTITELYKIFKE EEEEECCCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCEEEEECHHHHHHHHHHHCC PSINQYNVIIKVKSNKIQFDCQNITIISKLIDGNFPEYELFIPANNTKKIILNSNDLSES CCCCEEEEEEEEECCEEEEEECCEEEEEHHHCCCCCCEEEEEECCCCEEEEECCCCHHHH IERVSTIAVEKSKIVILDLDHHAITISAYGNAQCKAKELLLRHQHNNKNDQHQSSKQEVE HHHHHHEEEECCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH KYEYIGDDQLTIAFNAKYLLDVLSVCNNIKIPIEFKDSISPALIQLEEKNTSATFIIMPV HHHCCCCCEEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEC SVPTQEFVSAPT CCCHHHHHCCCC >Mature Secondary Structure MNTKYPKVDHNDLVISDFNIKLDTKNFSRALNFCMPILEKKNVDQILSNVKLTHINDTVE CCCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECHHHH KRLEISATDGDIFIYQKLPIKISKNDISITLPLQALNEIVKKIPHDEFTIYCNQDNKMVQ CCEEEEECCCCEEEEEEECEEEECCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCCEEE IKVGEYLEFNLATLPINLFPVIEELTDADFIIHVTAMQLAQMIEYTKFAISTEETRYNLN EEECCEEEEEEEEECEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEEECCCCEEEEE GIYLHSKDYKSLIAVATDGHRLASAKCNIDTFKTNISNNDGFGVILPRKTITELYKIFKE EEEEECCCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCEEEEECHHHHHHHHHHHCC PSINQYNVIIKVKSNKIQFDCQNITIISKLIDGNFPEYELFIPANNTKKIILNSNDLSES CCCCEEEEEEEEECCEEEEEECCEEEEEHHHCCCCCCEEEEEECCCCEEEEECCCCHHHH IERVSTIAVEKSKIVILDLDHHAITISAYGNAQCKAKELLLRHQHNNKNDQHQSSKQEVE HHHHHHEEEECCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH KYEYIGDDQLTIAFNAKYLLDVLSVCNNIKIPIEFKDSISPALIQLEEKNTSATFIIMPV HHHCCCCCEEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEC SVPTQEFVSAPT CCCHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]