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The map label for this gene is leuS [H]

Identifier: 189183513

GI number: 189183513

Start: 627669

End: 627932

Strand: Direct

Name: leuS [H]

Synonym: OTT_0606

Alternate gene names: 189183513

Gene position: 627669-627932 (Clockwise)

Preceding gene: 189183512

Following gene: 189183514

Centisome position: 31.24

GC content: 29.17

Gene sequence:

>264_bases
TTGTGCTCAAACCTCGTTGTAAATGACTATATATATGTAAATACTATACCAAAAATTCAAGAATTTATTAATAAATGCAG
TAACATTGGCACATTAAATGTTAATATTGATAAAATGAGTAAAATTGCCGTGCTAATAAATCTTATAGAATTGACTGTTA
TTCTTAGTAATTTTGTCTTAATGGATTATGGTACTGGGGCATTATTTGGATGTCCAACACGGGATGAGAAGGATTATGCT
GAAGAATTTTTGCACAACACATAA

Upstream 100 bases:

>100_bases
AGCTTGAAATCATTTTTTCAATAGGATTTAAATCAGGAGAATAAGGTAGCAGAAAAATAACTTTACAACCAACAGATTTT
ATTAATTTTATTGCTTCTTT

Downstream 100 bases:

>100_bases
ATTCTTCTAATTATAATTAGACATTATCTCTTGTAGACTTTTCATCTTTTTTCTTATCCTAAACTGACATTAAAAGTGAT
TTTTAATTTTTTACTGAAGT

Product: leucyl-tRNA synthetase

Products: NA

Alternate protein names: Leucine--tRNA ligase; LeuRS [H]

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MCSNLVVNDYIYVNTIPKIQEFINKCSNIGTLNVNIDKMSKIAVLINLIELTVILSNFVLMDYGTGALFGCPTRDEKDYA
EEFLHNT

Sequences:

>Translated_87_residues
MCSNLVVNDYIYVNTIPKIQEFINKCSNIGTLNVNIDKMSKIAVLINLIELTVILSNFVLMDYGTGALFGCPTRDEKDYA
EEFLHNT
>Mature_87_residues
MCSNLVVNDYIYVNTIPKIQEFINKCSNIGTLNVNIDKMSKIAVLINLIELTVILSNFVLMDYGTGALFGCPTRDEKDYA
EEFLHNT

Specific function: Unknown

COG id: COG0495

COG function: function code J; Leucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002300
- InterPro:   IPR002302
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.4 [H]

Molecular weight: Translated: 9822; Mature: 9822

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSNLVVNDYIYVNTIPKIQEFINKCSNIGTLNVNIDKMSKIAVLINLIELTVILSNFVL
CCCCEEECCEEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHE
MDYGTGALFGCPTRDEKDYAEEFLHNT
EECCCCCEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MCSNLVVNDYIYVNTIPKIQEFINKCSNIGTLNVNIDKMSKIAVLINLIELTVILSNFVL
CCCCEEECCEEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHE
MDYGTGALFGCPTRDEKDYAEEFLHNT
EECCCCCEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA