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The map label for this gene is recG [H]

Identifier: 187918444

GI number: 187918444

Start: 606514

End: 608577

Strand: Direct

Name: recG [H]

Synonym: BH0581

Alternate gene names: 187918444

Gene position: 606514-608577 (Clockwise)

Preceding gene: 187918443

Following gene: 187918446

Centisome position: 65.76

GC content: 30.57

Gene sequence:

>2064_bases
GTGTTTTTACATGAATTTAAATATGACCTGCAAGGTATAAGTGGCCTTGGTAAGAAAGGGCTTGAGAGATTAAATAGTCT
TCACATTACAAATATCAGAGAACTTATAGAATATTTTCCTAAAAAATATGAGGATCGTAAAAATATAAAAACTTTCCCAG
ATTCACTGGAGGTGAGAAATTGCGAACTCATGACAGTTTTTACTGTTTTAGAACATAGAGATTTTGGAAATAATTTTAAA
AGGAATTTAAAACTTATAGCTCAGAGTGAAAATAATGAGATATTTGAAATTCTTCTTTTTAATAGGGGATTCTTGGAAGG
GGTTTTTAAGGTAGGTCAAAAATTTTATATTTATTCTAAGTTCAATTACAACGATTATACTCAGATGTGGAGTTGCTCTA
ATTTTGATAGTGAAGTGTTTAGTTGTAATCCTGAAAGATTTAAAAAAATTATACCAGTTTATTCTCTTAGCGAAGGACTA
ACTTCTAAGAAAATATCGTCTTATGTAAAAGAAGCCCTTGTTTATTTTTTAAAGTTTGGGCAGTCAGACGTTCCTGAATT
CTTGATAAATAAGTATTCATTGTTGCCCTTTCATGAGGCTTTAAATGAGATTCATTTTCCAAGTTCATTTGAAATGCTTG
AAAAGGCAAAAAAGACTTTGATTTATAGGGAGATTTTTTTGCTTCAGTTTTTTTCAAGAGGAAAAAGTTCTGTATTTTTC
TTAAGGAAAGAAAGAAATTTACCTAGGAATTTGCTTGATCAAATTATTTTAAAACTTCCATTTAAGCTTACAAAAGATCA
AAGAGTTGCAATTGATGAAATAATTAATGATCTTGAAAGTAATAAGCCAATGAATAGATTATTGCAAGGTGATGTTGGAA
GTGGGAAAACCATTGTTGCTTTTCTCTCTAGCATTCCTTTAATTGAAGCTGGATATCAAGTTGCGTTGATGGTGCCTACT
GATCTTTTGGCGCGGCAACATTATAATAATTTAGCAAATATATTAAAAGATTTTAATGTTTCTATAGCTTTTTTAACTGG
TAGTTTAAAAAAGAGAGATAGAGATGAGGTTTTAGAGAAAATTCAAAGTGGAACTTATAGTTTAGTAATTGGAACTCATG
CTATTTTTTCTCAGGGAACAAAATTTAAAAGATTAGCTTATATCATTATTGATGAACAGCATAAATTTGGTGTTGAGCAG
AGAGAGGAGCTTAAAAATAAGGGAGAGGAGGTTGATGTGCTTTTAATCTCAGCAACTCCTATTCCTAGAAGCTTAGCTTT
GACCCTTTTTGGCGATCTTGAGATATCTTTAATTAGAAGAGGTCCTGCAGGTCGAATACCTGTTACTACGTATTTAGCAA
AACATGGCAATGAAGAGAAGGTATATGAATTTTTAAAAAATGAACTTGCAAAAGGACATCAGGTTTATTTTGTTTATCCC
CTAATATCATCTTCACAGAGGTTTAATTTAAAAGATGCTACTAGTATGTGTTTAAATCTTAAGAATATTTTTGTTGAGTA
TTCTGTTGAAATGATTCATTCTAAGCTTGAATCTCATGTTAAGGAAGAGATTATGCATGATTTTTACTTAAAGAGAATAG
ATATTTTAGTTGCAACGAGTGTTATTGAAGTTGGTATTGATTGCCCAAATGCGACTTGTATGGTAGTAGAGCATGCTGAG
CGTTTTGGACTCTCTACTTTGCATCAGATTAGAGGACGTGTTGGTAGAGGTAGCTTAAAGTCTTTTTTGTTTTTGCTTTA
TAAGGAACCTTTAACAGAATCGGGAAAATTTAGACTTAAGACTATAAAGGAAAATATAGATGGATTTAAAATAGCAGAGG
AAGATCTTAAATTAAGAGGTCCTGGCAATTTATTTGGTCTTGAGCAAACTGGTTATTTAAAACTTAAGATAGCTGATTTT
ATTGAAGATAGAGAAGTTGTAAGATTGATTAGAGAAGAACTTAATATGTTTTCTTTAAATAAGGCTTATTATAATAAATC
AGATATTGAATTACTTGATAGTCTTTTACTCTCATATTTAAGATCTGTTGCTAAAGAGAGTTAA

Upstream 100 bases:

>100_bases
TTGTGGCAGGAGCATTGTTATTGGCATTTATAATCATTTGTGAGCAAGCTATATGGGCTATTAGTATTCTAGGCTTTTAT
TTACCTTTTTAGGAATTTTA

Downstream 100 bases:

>100_bases
TATTAATTTGTATATTTTTGAATTAACCGTGAAAGTTCTTTTTTATTTTCATGCCAAAATTTGAGAAGTTTATATTGTAA
ATTGTTGAAATATTTTTTTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MFLHEFKYDLQGISGLGKKGLERLNSLHITNIRELIEYFPKKYEDRKNIKTFPDSLEVRNCELMTVFTVLEHRDFGNNFK
RNLKLIAQSENNEIFEILLFNRGFLEGVFKVGQKFYIYSKFNYNDYTQMWSCSNFDSEVFSCNPERFKKIIPVYSLSEGL
TSKKISSYVKEALVYFLKFGQSDVPEFLINKYSLLPFHEALNEIHFPSSFEMLEKAKKTLIYREIFLLQFFSRGKSSVFF
LRKERNLPRNLLDQIILKLPFKLTKDQRVAIDEIINDLESNKPMNRLLQGDVGSGKTIVAFLSSIPLIEAGYQVALMVPT
DLLARQHYNNLANILKDFNVSIAFLTGSLKKRDRDEVLEKIQSGTYSLVIGTHAIFSQGTKFKRLAYIIIDEQHKFGVEQ
REELKNKGEEVDVLLISATPIPRSLALTLFGDLEISLIRRGPAGRIPVTTYLAKHGNEEKVYEFLKNELAKGHQVYFVYP
LISSSQRFNLKDATSMCLNLKNIFVEYSVEMIHSKLESHVKEEIMHDFYLKRIDILVATSVIEVGIDCPNATCMVVEHAE
RFGLSTLHQIRGRVGRGSLKSFLFLLYKEPLTESGKFRLKTIKENIDGFKIAEEDLKLRGPGNLFGLEQTGYLKLKIADF
IEDREVVRLIREELNMFSLNKAYYNKSDIELLDSLLLSYLRSVAKES

Sequences:

>Translated_687_residues
MFLHEFKYDLQGISGLGKKGLERLNSLHITNIRELIEYFPKKYEDRKNIKTFPDSLEVRNCELMTVFTVLEHRDFGNNFK
RNLKLIAQSENNEIFEILLFNRGFLEGVFKVGQKFYIYSKFNYNDYTQMWSCSNFDSEVFSCNPERFKKIIPVYSLSEGL
TSKKISSYVKEALVYFLKFGQSDVPEFLINKYSLLPFHEALNEIHFPSSFEMLEKAKKTLIYREIFLLQFFSRGKSSVFF
LRKERNLPRNLLDQIILKLPFKLTKDQRVAIDEIINDLESNKPMNRLLQGDVGSGKTIVAFLSSIPLIEAGYQVALMVPT
DLLARQHYNNLANILKDFNVSIAFLTGSLKKRDRDEVLEKIQSGTYSLVIGTHAIFSQGTKFKRLAYIIIDEQHKFGVEQ
REELKNKGEEVDVLLISATPIPRSLALTLFGDLEISLIRRGPAGRIPVTTYLAKHGNEEKVYEFLKNELAKGHQVYFVYP
LISSSQRFNLKDATSMCLNLKNIFVEYSVEMIHSKLESHVKEEIMHDFYLKRIDILVATSVIEVGIDCPNATCMVVEHAE
RFGLSTLHQIRGRVGRGSLKSFLFLLYKEPLTESGKFRLKTIKENIDGFKIAEEDLKLRGPGNLFGLEQTGYLKLKIADF
IEDREVVRLIREELNMFSLNKAYYNKSDIELLDSLLLSYLRSVAKES
>Mature_687_residues
MFLHEFKYDLQGISGLGKKGLERLNSLHITNIRELIEYFPKKYEDRKNIKTFPDSLEVRNCELMTVFTVLEHRDFGNNFK
RNLKLIAQSENNEIFEILLFNRGFLEGVFKVGQKFYIYSKFNYNDYTQMWSCSNFDSEVFSCNPERFKKIIPVYSLSEGL
TSKKISSYVKEALVYFLKFGQSDVPEFLINKYSLLPFHEALNEIHFPSSFEMLEKAKKTLIYREIFLLQFFSRGKSSVFF
LRKERNLPRNLLDQIILKLPFKLTKDQRVAIDEIINDLESNKPMNRLLQGDVGSGKTIVAFLSSIPLIEAGYQVALMVPT
DLLARQHYNNLANILKDFNVSIAFLTGSLKKRDRDEVLEKIQSGTYSLVIGTHAIFSQGTKFKRLAYIIIDEQHKFGVEQ
REELKNKGEEVDVLLISATPIPRSLALTLFGDLEISLIRRGPAGRIPVTTYLAKHGNEEKVYEFLKNELAKGHQVYFVYP
LISSSQRFNLKDATSMCLNLKNIFVEYSVEMIHSKLESHVKEEIMHDFYLKRIDILVATSVIEVGIDCPNATCMVVEHAE
RFGLSTLHQIRGRVGRGSLKSFLFLLYKEPLTESGKFRLKTIKENIDGFKIAEEDLKLRGPGNLFGLEQTGYLKLKIADF
IEDREVVRLIREELNMFSLNKAYYNKSDIELLDSLLLSYLRSVAKES

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=671, Percent_Identity=33.3830104321908, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1787357, Length=380, Percent_Identity=35.2631578947368, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79410; Mature: 79410

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLHEFKYDLQGISGLGKKGLERLNSLHITNIRELIEYFPKKYEDRKNIKTFPDSLEVRN
CCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
CELMTVFTVLEHRDFGNNFKRNLKLIAQSENNEIFEILLFNRGFLEGVFKVGQKFYIYSK
CHHHHHHHHHHHCCCCCCHHHCEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEEEEEE
FNYNDYTQMWSCSNFDSEVFSCNPERFKKIIPVYSLSEGLTSKKISSYVKEALVYFLKFG
CCCCCHHHHCCCCCCCCHHHCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC
QSDVPEFLINKYSLLPFHEALNEIHFPSSFEMLEKAKKTLIYREIFLLQFFSRGKSSVFF
CCCCHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LRKERNLPRNLLDQIILKLPFKLTKDQRVAIDEIINDLESNKPMNRLLQGDVGSGKTIVA
EECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHH
FLSSIPLIEAGYQVALMVPTDLLARQHYNNLANILKDFNVSIAFLTGSLKKRDRDEVLEK
HHHCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
IQSGTYSLVIGTHAIFSQGTKFKRLAYIIIDEQHKFGVEQREELKNKGEEVDVLLISATP
HHCCCEEEEEECHHHHHCCCCEEEEEEEEEECHHHCCCHHHHHHHCCCCEEEEEEEECCC
IPRSLALTLFGDLEISLIRRGPAGRIPVTTYLAKHGNEEKVYEFLKNELAKGHQVYFVYP
CCCHHEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEE
LISSSQRFNLKDATSMCLNLKNIFVEYSVEMIHSKLESHVKEEIMHDFYLKRIDILVATS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIEVGIDCPNATCMVVEHAERFGLSTLHQIRGRVGRGSLKSFLFLLYKEPLTESGKFRLK
HHHHCCCCCCCEEEEEHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEE
TIKENIDGFKIAEEDLKLRGPGNLFGLEQTGYLKLKIADFIEDREVVRLIREELNMFSLN
EHHCCCCCCEEECCCCEECCCCCEECCCCCCEEEEEHHHHHCHHHHHHHHHHHHHHEEEH
KAYYNKSDIELLDSLLLSYLRSVAKES
HHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLHEFKYDLQGISGLGKKGLERLNSLHITNIRELIEYFPKKYEDRKNIKTFPDSLEVRN
CCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
CELMTVFTVLEHRDFGNNFKRNLKLIAQSENNEIFEILLFNRGFLEGVFKVGQKFYIYSK
CHHHHHHHHHHHCCCCCCHHHCEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEEEEEE
FNYNDYTQMWSCSNFDSEVFSCNPERFKKIIPVYSLSEGLTSKKISSYVKEALVYFLKFG
CCCCCHHHHCCCCCCCCHHHCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC
QSDVPEFLINKYSLLPFHEALNEIHFPSSFEMLEKAKKTLIYREIFLLQFFSRGKSSVFF
CCCCHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LRKERNLPRNLLDQIILKLPFKLTKDQRVAIDEIINDLESNKPMNRLLQGDVGSGKTIVA
EECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHH
FLSSIPLIEAGYQVALMVPTDLLARQHYNNLANILKDFNVSIAFLTGSLKKRDRDEVLEK
HHHCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
IQSGTYSLVIGTHAIFSQGTKFKRLAYIIIDEQHKFGVEQREELKNKGEEVDVLLISATP
HHCCCEEEEEECHHHHHCCCCEEEEEEEEEECHHHCCCHHHHHHHCCCCEEEEEEEECCC
IPRSLALTLFGDLEISLIRRGPAGRIPVTTYLAKHGNEEKVYEFLKNELAKGHQVYFVYP
CCCHHEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEE
LISSSQRFNLKDATSMCLNLKNIFVEYSVEMIHSKLESHVKEEIMHDFYLKRIDILVATS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIEVGIDCPNATCMVVEHAERFGLSTLHQIRGRVGRGSLKSFLFLLYKEPLTESGKFRLK
HHHHCCCCCCCEEEEEHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEE
TIKENIDGFKIAEEDLKLRGPGNLFGLEQTGYLKLKIADFIEDREVVRLIREELNMFSLN
EHHCCCCCCEEECCCCEECCCCCEECCCCCCEEEEEHHHHHCHHHHHHHHHHHHHHEEEH
KAYYNKSDIELLDSLLLSYLRSVAKES
HHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]