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The map label for this gene is zupT

Identifier: 187735974

GI number: 187735974

Start: 1773388

End: 1774200

Strand: Reverse

Name: zupT

Synonym: Amuc_1483

Alternate gene names: 187735974

Gene position: 1774200-1773388 (Counterclockwise)

Preceding gene: 187735975

Following gene: 187735973

Centisome position: 66.6

GC content: 56.21

Gene sequence:

>813_bases
ATGGACCTTTCCGCCGACCACATCCTCGTTGTCTTCCTGCTCACCACGCTGGCTGGTCTTGCTACCGGCATAGGAGGCTT
CATCGCCTTCTTCATGAAAAGGACGGATACAAAGGCACTTACTTTTGCCCTGGGATTATCCGGCGGAGTCATGGTGTATA
TCTCCCTGGTGGAACTGCTGGGAGAAGCCCAGCACAGGTTGATGGAGTTCGAAGGCCATACGGCAGGTTCCTGGATCGCC
ATTGCTTCCTTCTTCGGGGGAATTGCCGTGGCGGCTCTGATTGATTACCTGGTTCCGGAAGACGAAAACCCGCACGAAGC
GCGCGGACCGGAAGACATCCATGGACAGGCCAGCGGTGAATTTTCCTCATCCCGAATTAAAAGGTCCGGCATTCTGTTCG
CCCTGGCCATCGGCATCCACAATTTCCCGGAAGGAATCGCCACCTTTGCCGCCGGATTGGACTCCCTGACTTTAGGCACC
TCCATCGCCCTGGCCGTAGCCGTCCATAACATTCCGGAAGGAATAGCCGTGGCGGTACCTCTTTACTACGGTACGGGCAG
CCGTAAAAAGGCCCTTTTTTATTCCTTTCTCTCCGGTCTGGCGGAACCGGTGGGCGCGGCCATCGCCATGTTCTTCCTGT
TCCACTTCCTCACACCTACCGTACTTGCGGTTCTCTTTGCCTCCGTCGCGGGAATCATGGTCTTCATCTCCTTTGACGAG
CTGCTGCCCATGGCGGAACGCTGGGGACACCATCACATTTCCATCATGGGCATCATCGCCGGAATGCTGCTGATGGCGAT
TGTCCTGATCTGA

Upstream 100 bases:

>100_bases
GCGCCATCCGGGCCACGAAGATGATCGTTCCCACGGCTCCCGCAAAATAATACACCCCTTTCTTTACTGCCGGGGTCATC
CCTGCCCGGCAGGTGCACGC

Downstream 100 bases:

>100_bases
ACCGGCTGCAGGAGGGAACTTTCCATGTCCTGGGCACAGACGCATTGAGCATTCCCCGGCATCAGGGAGTCTAAACGGAA
ACCCCCTTTTCATCCATGCC

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDLSADHILVVFLLTTLAGLATGIGGFIAFFMKRTDTKALTFALGLSGGVMVYISLVELLGEAQHRLMEFEGHTAGSWIA
IASFFGGIAVAALIDYLVPEDENPHEARGPEDIHGQASGEFSSSRIKRSGILFALAIGIHNFPEGIATFAAGLDSLTLGT
SIALAVAVHNIPEGIAVAVPLYYGTGSRKKALFYSFLSGLAEPVGAAIAMFFLFHFLTPTVLAVLFASVAGIMVFISFDE
LLPMAERWGHHHISIMGIIAGMLLMAIVLI

Sequences:

>Translated_270_residues
MDLSADHILVVFLLTTLAGLATGIGGFIAFFMKRTDTKALTFALGLSGGVMVYISLVELLGEAQHRLMEFEGHTAGSWIA
IASFFGGIAVAALIDYLVPEDENPHEARGPEDIHGQASGEFSSSRIKRSGILFALAIGIHNFPEGIATFAAGLDSLTLGT
SIALAVAVHNIPEGIAVAVPLYYGTGSRKKALFYSFLSGLAEPVGAAIAMFFLFHFLTPTVLAVLFASVAGIMVFISFDE
LLPMAERWGHHHISIMGIIAGMLLMAIVLI
>Mature_270_residues
MDLSADHILVVFLLTTLAGLATGIGGFIAFFMKRTDTKALTFALGLSGGVMVYISLVELLGEAQHRLMEFEGHTAGSWIA
IASFFGGIAVAALIDYLVPEDENPHEARGPEDIHGQASGEFSSSRIKRSGILFALAIGIHNFPEGIATFAAGLDSLTLGT
SIALAVAVHNIPEGIAVAVPLYYGTGSRKKALFYSFLSGLAEPVGAAIAMFFLFHFLTPTVLAVLFASVAGIMVFISFDE
LLPMAERWGHHHISIMGIIAGMLLMAIVLI

Specific function: Mediates zinc uptake. May also transport other divalent cations

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily

Homologues:

Organism=Homo sapiens, GI229577422, Length=144, Percent_Identity=31.9444444444444, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI229577418, Length=144, Percent_Identity=31.9444444444444, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789419, Length=262, Percent_Identity=40.0763358778626, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17507805, Length=148, Percent_Identity=34.4594594594595, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652846, Length=166, Percent_Identity=36.7469879518072, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZUPT_AKKM8 (B2UL32)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001878086.1
- GeneID:   6274660
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1483
- HOGENOM:   HBG620552
- OMA:   VSVPIYY
- HAMAP:   MF_00548
- InterPro:   IPR003689

Pfam domain/function: PF02535 Zip

EC number: NA

Molecular weight: Translated: 28623; Mature: 28623

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1abb7cd0)-; HASH(0x1dae00e8)-; HASH(0x1da6b63c)-; HASH(0x1dae2098)-; HASH(0x1d5de1bc)-; HASH(0x1d051824)-; HASH(0x1c8ba904)-; HASH(0x1da27e98)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSADHILVVFLLTTLAGLATGIGGFIAFFMKRTDTKALTFALGLSGGVMVYISLVELL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
GEAQHRLMEFEGHTAGSWIAIASFFGGIAVAALIDYLVPEDENPHEARGPEDIHGQASGE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
FSSSRIKRSGILFALAIGIHNFPEGIATFAAGLDSLTLGTSIALAVAVHNIPEGIAVAVP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LYYGTGSRKKALFYSFLSGLAEPVGAAIAMFFLFHFLTPTVLAVLFASVAGIMVFISFDE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPMAERWGHHHISIMGIIAGMLLMAIVLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MDLSADHILVVFLLTTLAGLATGIGGFIAFFMKRTDTKALTFALGLSGGVMVYISLVELL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
GEAQHRLMEFEGHTAGSWIAIASFFGGIAVAALIDYLVPEDENPHEARGPEDIHGQASGE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
FSSSRIKRSGILFALAIGIHNFPEGIATFAAGLDSLTLGTSIALAVAVHNIPEGIAVAVP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LYYGTGSRKKALFYSFLSGLAEPVGAAIAMFFLFHFLTPTVLAVLFASVAGIMVFISFDE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPMAERWGHHHISIMGIIAGMLLMAIVLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA