Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 187735449

GI number: 187735449

Start: 1128857

End: 1130005

Strand: Reverse

Name: nagA [H]

Synonym: Amuc_0948

Alternate gene names: 187735449

Gene position: 1130005-1128857 (Counterclockwise)

Preceding gene: 187735450

Following gene: 187735448

Centisome position: 42.42

GC content: 61.1

Gene sequence:

>1149_bases
ATGAAGACACTCATTAAAAACGCACGCATCATCTCCCCCGGCATCGATATGCCCGGGGCTGCCGTGGAAATGGAAGGCAA
AACCATTACCGCCGTCTATCCCGCCGGGAGCGAACTTCCCGCCGCAGACAAGGTCGTGGATGCGGAAGGCCGCATGCTCC
TTCCCGGCTTCATTGACATCCACAGCCACGGCGCCGGCGGCTGCGACACCTGCGACGCCAAGCTGGAAAGCCTCCGCACC
ATTGCGGAATGCAAAATGAAGGAAGGCGTCACTTCCTGGCTGCCGACCACCCTCACCCTGTCCCCCAAGGTGCTGGAAGA
CGTATGCGCCTCCGTGGCGGAATACATGAAGAACCAGGAATTCGCCAAGACTCCCGGCGTCCACCTGGAAGGGCCGTTCA
TCAACCCCAAATGCTGCGGCGCGCAGAATCCCGCCTTTGTCCGCCAGCCGGATTACGATGAAGTAGCCAACCTGAACTCC
ATCGCCAAGGTGCTGCTGGTCTCCCTGGCGCCGGAAATGCCCGGAGCCATTGAATTCATTGAGAAAGCCACGGCCAACGG
CATCCGCTGCTCCGCCGGGCACAGCGCCGCCACCCATGAGGACTTCAACAGGGCGAAGTCTGCGGGGCTGGCGCACCTGA
CCCACTACTGCAACCAGATGTCCCCCCTGCACCACCGTGAAATCGGCCTGGTGGGGTCCGGCCTGCTGGACAGGGAAATC
AAGATTGAAATCATCTGCGACACCATCCACCTCTGCGCGGACATGCTCAAAACCGTGTTCAAGAACAAGGATTCTGACCA
GATGCTGATGATTACGGACTCCCTGGCCTGCTCCTGGATGCCGGACGGCCCCGGAGACCTGGGCGGCCTGCCCATCATCG
TGAAAGACGGCGTGGCCCGTCTGCAGGAATCCGGCGCCCTGGCCGGCAGCACCCTCAAATACGCCCACGGCCTGAAAAAC
GTGCACCGCCTGACAGGGAAACCCCTCAGCGACCTGGTGAAAGCCACCTCCTGGAACCAGGCGCAGTCCCTGGGCCTGGA
AGGCCTGGGCAAAATCGCCCCCGGCTTCACGGCGGACATGGTTCTGCTGGACGATGACTTCAATACCTGCAAGGTATTCA
TCGACGGCGTGGAAAAATACAGCGCGTAA

Upstream 100 bases:

>100_bases
CCCATTCCCGGTTTTCCGCAGGAAGCGGAGGCCAGGCGGGAAGACGCGGACGAACGGAGAAAAACGACGATAAACATCCA
TCCAACAACCATTCATTTTT

Downstream 100 bases:

>100_bases
CCGCGTTTCCGCGCGCCGGAAGGAGACGTCCCGCCCCTTCCGGCGCGCCTTCCTCCCTTTTACCATATTTCAACATTCAC
CTCCATGGCTATTACCATTG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKTLIKNARIISPGIDMPGAAVEMEGKTITAVYPAGSELPAADKVVDAEGRMLLPGFIDIHSHGAGGCDTCDAKLESLRT
IAECKMKEGVTSWLPTTLTLSPKVLEDVCASVAEYMKNQEFAKTPGVHLEGPFINPKCCGAQNPAFVRQPDYDEVANLNS
IAKVLLVSLAPEMPGAIEFIEKATANGIRCSAGHSAATHEDFNRAKSAGLAHLTHYCNQMSPLHHREIGLVGSGLLDREI
KIEIICDTIHLCADMLKTVFKNKDSDQMLMITDSLACSWMPDGPGDLGGLPIIVKDGVARLQESGALAGSTLKYAHGLKN
VHRLTGKPLSDLVKATSWNQAQSLGLEGLGKIAPGFTADMVLLDDDFNTCKVFIDGVEKYSA

Sequences:

>Translated_382_residues
MKTLIKNARIISPGIDMPGAAVEMEGKTITAVYPAGSELPAADKVVDAEGRMLLPGFIDIHSHGAGGCDTCDAKLESLRT
IAECKMKEGVTSWLPTTLTLSPKVLEDVCASVAEYMKNQEFAKTPGVHLEGPFINPKCCGAQNPAFVRQPDYDEVANLNS
IAKVLLVSLAPEMPGAIEFIEKATANGIRCSAGHSAATHEDFNRAKSAGLAHLTHYCNQMSPLHHREIGLVGSGLLDREI
KIEIICDTIHLCADMLKTVFKNKDSDQMLMITDSLACSWMPDGPGDLGGLPIIVKDGVARLQESGALAGSTLKYAHGLKN
VHRLTGKPLSDLVKATSWNQAQSLGLEGLGKIAPGFTADMVLLDDDFNTCKVFIDGVEKYSA
>Mature_382_residues
MKTLIKNARIISPGIDMPGAAVEMEGKTITAVYPAGSELPAADKVVDAEGRMLLPGFIDIHSHGAGGCDTCDAKLESLRT
IAECKMKEGVTSWLPTTLTLSPKVLEDVCASVAEYMKNQEFAKTPGVHLEGPFINPKCCGAQNPAFVRQPDYDEVANLNS
IAKVLLVSLAPEMPGAIEFIEKATANGIRCSAGHSAATHEDFNRAKSAGLAHLTHYCNQMSPLHHREIGLVGSGLLDREI
KIEIICDTIHLCADMLKTVFKNKDSDQMLMITDSLACSWMPDGPGDLGGLPIIVKDGVARLQESGALAGSTLKYAHGLKN
VHRLTGKPLSDLVKATSWNQAQSLGLEGLGKIAPGFTADMVLLDDDFNTCKVFIDGVEKYSA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=28.7958115183246, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI224922791, Length=382, Percent_Identity=28.7958115183246, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1786892, Length=368, Percent_Identity=33.1521739130435, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=362, Percent_Identity=31.2154696132597, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19920392, Length=346, Percent_Identity=30.635838150289, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=29.2479108635098, Blast_Score=131, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40827; Mature: 40827

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIKNARIISPGIDMPGAAVEMEGKTITAVYPAGSELPAADKVVDAEGRMLLPGFIDI
CCCHHCCCEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCEECCCCCEECCCEEEE
HSHGAGGCDTCDAKLESLRTIAECKMKEGVTSWLPTTLTLSPKVLEDVCASVAEYMKNQE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEECHHHHHHHHHHHHHHHCCCC
FAKTPGVHLEGPFINPKCCGAQNPAFVRQPDYDEVANLNSIAKVLLVSLAPEMPGAIEFI
HHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKATANGIRCSAGHSAATHEDFNRAKSAGLAHLTHYCNQMSPLHHREIGLVGSGLLDREI
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEECCCCCCCEE
KIEIICDTIHLCADMLKTVFKNKDSDQMLMITDSLACSWMPDGPGDLGGLPIIVKDGVAR
EEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCCCCCCEEECCHHHH
LQESGALAGSTLKYAHGLKNVHRLTGKPLSDLVKATSWNQAQSLGLEGLGKIAPGFTADM
HHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCHHHHHHCCCCCCEEE
VLLDDDFNTCKVFIDGVEKYSA
EEEECCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MKTLIKNARIISPGIDMPGAAVEMEGKTITAVYPAGSELPAADKVVDAEGRMLLPGFIDI
CCCHHCCCEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCEECCCCCEECCCEEEE
HSHGAGGCDTCDAKLESLRTIAECKMKEGVTSWLPTTLTLSPKVLEDVCASVAEYMKNQE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEECHHHHHHHHHHHHHHHCCCC
FAKTPGVHLEGPFINPKCCGAQNPAFVRQPDYDEVANLNSIAKVLLVSLAPEMPGAIEFI
HHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKATANGIRCSAGHSAATHEDFNRAKSAGLAHLTHYCNQMSPLHHREIGLVGSGLLDREI
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEECCCCCCCEE
KIEIICDTIHLCADMLKTVFKNKDSDQMLMITDSLACSWMPDGPGDLGGLPIIVKDGVAR
EEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCCCCCCEEECCHHHH
LQESGALAGSTLKYAHGLKNVHRLTGKPLSDLVKATSWNQAQSLGLEGLGKIAPGFTADM
HHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCHHHHHHCCCCCCEEE
VLLDDDFNTCKVFIDGVEKYSA
EEEECCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA