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The map label for this gene is coaD

Identifier: 182680833

GI number: 182680833

Start: 351685

End: 352173

Strand: Direct

Name: coaD

Synonym: XfasM23_0268

Alternate gene names: 182680833

Gene position: 351685-352173 (Clockwise)

Preceding gene: 182680832

Following gene: 182680834

Centisome position: 13.87

GC content: 54.19

Gene sequence:

>489_bases
ATGAGCGTGGTTAATCGCCGCATCGCCGTCTATCCTGGCACCTTCGATCCGATCACTAATGGTCACATTGATTTAGTGAG
TCGTGCTGCTCCGCTGTTTGAGTCGGTTGTGGTTGGTGTTGCGCAGAGTCCATCCAAGGGACCTTCTCTGCCGTTGCAGC
AGCGTGTGACTCTGGCGCGTGAGGCGTTGTGCCAGCATGAAAATGTGCAGGTCATTGGGTTCGATACATTGTTAGCGCAT
TTTGTGCGTCACGTTGGCGCGGGTGTGTTGCTGCGCGGCTTGCGTGCGGTTTCGGATTTCGAGTATGAGTTCCAGATGGC
GAGTATGAATCGTCATCTGATCCCTGAAGTTGAGACATTGTTTCTGACTCCGGCGGAGCAGCATAGTTTTATTTCGTCTT
CGCTGGTGCGTGAGATTGCGCGGCTTGGCGGAGATGTTTCCGGCTTTGCACCTGCGGCGGTCGTTGCGGCGTTACGTCAG
AATCTTTAG

Upstream 100 bases:

>100_bases
GGGAGTTGCATCGTGACGGTCGCACGCGTGAGGTGTGCTATGCGTTGTATCGGTATCCGGCTGTTACACTGCCTGTTGGT
TCTAAGTCAGTATCGTCTGT

Downstream 100 bases:

>100_bases
GGGTACACGATGTTTTTCTGTTTTATCCATAATCTGTAAGGCAAGAGCAATGAATAACATGTTGCGTGTGGTGGTGGTTG
CTTTGTTTGTTTTTGTTTTG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESVVVGVAQSPSKGPSLPLQQRVTLAREALCQHENVQVIGFDTLLAH
FVRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQ
NL

Sequences:

>Translated_162_residues
MSVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESVVVGVAQSPSKGPSLPLQQRVTLAREALCQHENVQVIGFDTLLAH
FVRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQ
NL
>Mature_161_residues
SVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESVVVGVAQSPSKGPSLPLQQRVTLAREALCQHENVQVIGFDTLLAHF
VRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQN
L

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=56.0509554140127, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_XYLF2 (B2I7J1)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828993.1
- ProteinModelPortal:   B2I7J1
- SMR:   B2I7J1
- GeneID:   6203735
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0268
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17584; Mature: 17453

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESVVVGVAQSPSKGPSLPLQQRVTLAR
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EALCQHENVQVIGFDTLLAHFVRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQNL
EECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESVVVGVAQSPSKGPSLPLQQRVTLAR
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EALCQHENVQVIGFDTLLAHFVRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQNL
EECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA