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The map label for this gene is dgk [H]

Identifier: 17547348

GI number: 17547348

Start: 2831919

End: 2832563

Strand: Direct

Name: dgk [H]

Synonym: RSc2629

Alternate gene names: 17547348

Gene position: 2831919-2832563 (Clockwise)

Preceding gene: 17547347

Following gene: 17547349

Centisome position: 76.2

GC content: 68.06

Gene sequence:

>645_bases
ATGGCACTCGATCATCTGCGCCGCATCGTCGTCGAAGGGCCGATCGGCGCCGGCAAGACGGCATTGGCGCAACGGCTGGC
CGATCACCTGCGTGCGGCCACGCTGTTCGAAACCCCCGAAGACAACCCCTTTCTCGCGCGCTTCTATGAAGAGCCCGCGC
GCTATGCGCTGCCGGTGCAGCTGCGCTTCCTGCTGCAGCGCGCGCAGCGGCTGGCCGCATGGCAGAAGGCCACGCTGGCC
GGCGAGCGCATCGTCGCCGACAGCTTCCTGCCGCGCGACCGCCTGTTCGCCCAGCTGACGCTGCCCGCCGACGAGCTCGC
GCTGTACGACGCCATGGCGCAAGCACTGGCCCTGCCGCCGCAGCGCATCGATCTCGTGGTCTGCCTGCAGGCGCGCGCCG
AAGACCTGCTGCCCCGCATCGCCAGGCGCGCCGTTCCTTACGAAGCGGGCATCGACGCGGAATACCTCGAACGCATCTGC
GCCGCGTACGGCGAGCTGTTTCTGTATTACGATGCCGCACCGACGCTGATCGTCGATACCGCCGCCTTCGATCCGGCCGG
CAACGACGACGATTTCCGCACCTTGCTCACCCGCATCGACGCCATGCGCGGGCCCAAGGAATTCATCAAGCTCGCGACCC
GGTAG

Upstream 100 bases:

>100_bases
CGTCGCCGACCAGGTCATCGAGAAGATGACGCTGTGCCAGTGCATGCGCGCCAAGCCGGCCGCCTGACACCTCTTTTCCA
CTCTCCCGAATCCAGACGCG

Downstream 100 bases:

>100_bases
CAGGTCCATCGCATGGCCTGCCTGGAAGGTCGCGGCGCTCAACCTGATCCCAGTCCATGAGCAGCTATCTCCAGGAATCC
ACCCGCAAGGCCGTGACCGT

Product: deoxyguanosine kinase (DGUO kinase) (DGK) protein

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MALDHLRRIVVEGPIGAGKTALAQRLADHLRAATLFETPEDNPFLARFYEEPARYALPVQLRFLLQRAQRLAAWQKATLA
GERIVADSFLPRDRLFAQLTLPADELALYDAMAQALALPPQRIDLVVCLQARAEDLLPRIARRAVPYEAGIDAEYLERIC
AAYGELFLYYDAAPTLIVDTAAFDPAGNDDDFRTLLTRIDAMRGPKEFIKLATR

Sequences:

>Translated_214_residues
MALDHLRRIVVEGPIGAGKTALAQRLADHLRAATLFETPEDNPFLARFYEEPARYALPVQLRFLLQRAQRLAAWQKATLA
GERIVADSFLPRDRLFAQLTLPADELALYDAMAQALALPPQRIDLVVCLQARAEDLLPRIARRAVPYEAGIDAEYLERIC
AAYGELFLYYDAAPTLIVDTAAFDPAGNDDDFRTLLTRIDAMRGPKEFIKLATR
>Mature_213_residues
ALDHLRRIVVEGPIGAGKTALAQRLADHLRAATLFETPEDNPFLARFYEEPARYALPVQLRFLLQRAQRLAAWQKATLAG
ERIVADSFLPRDRLFAQLTLPADELALYDAMAQALALPPQRIDLVVCLQARAEDLLPRIARRAVPYEAGIDAEYLERICA
AYGELFLYYDAAPTLIVDTAAFDPAGNDDDFRTLLTRIDAMRGPKEFIKLATR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 23982; Mature: 23851

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDHLRRIVVEGPIGAGKTALAQRLADHLRAATLFETPEDNPFLARFYEEPARYALPVQ
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHCCHHH
LRFLLQRAQRLAAWQKATLAGERIVADSFLPRDRLFAQLTLPADELALYDAMAQALALPP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHEEECCCHHHHHHHHHHHHHHCCCH
QRIDLVVCLQARAEDLLPRIARRAVPYEAGIDAEYLERICAAYGELFLYYDAAPTLIVDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEC
AAFDPAGNDDDFRTLLTRIDAMRGPKEFIKLATR
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
ALDHLRRIVVEGPIGAGKTALAQRLADHLRAATLFETPEDNPFLARFYEEPARYALPVQ
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHCCHHH
LRFLLQRAQRLAAWQKATLAGERIVADSFLPRDRLFAQLTLPADELALYDAMAQALALPP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHEEECCCHHHHHHHHHHHHHHCCCH
QRIDLVVCLQARAEDLLPRIARRAVPYEAGIDAEYLERICAAYGELFLYYDAAPTLIVDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEC
AAFDPAGNDDDFRTLLTRIDAMRGPKEFIKLATR
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]