| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is polC [H]
Identifier: 169627433
GI number: 169627433
Start: 329582
End: 330565
Strand: Direct
Name: polC [H]
Synonym: MAB_0329
Alternate gene names: 169627433
Gene position: 329582-330565 (Clockwise)
Preceding gene: 169627432
Following gene: 169627434
Centisome position: 6.5
GC content: 65.96
Gene sequence:
>984_bases ATGCCGATCTGGGGGCAGACGCCCGACCACAGCCCCAAGTGGGTGGTGGTTGACCTGGAGACTTCAGGTTTCCAGCCGGG GCGGGCGCGTGTCATCAGCGTTGCGGCATTGGCGATGGATGCCGACGGGACCATCACCGACAGCGTGGTGAGTCTGCTCA ACCCCGGTGTCGATCCGGGCCCCACGCACGTCCACGGCCTCACCCCGGAGATGCTGGAGGGCCAGCCGGAGTTCTCCGAT ATCGCGCCCGATCTGATCGCGCTGCTGCGCGGGCGGACGTTGGTCGCGCACAACGTCGGCTTCGACTACTCGTTCCTGGC GGCCGAGGCCGAGCTGGTGGGAGCCGAACTGCCCACCGAGGCCGTCATGTGCACCGTCGAGCTGACGCGCCGTCTCGAAC TGGACACACCCAACCTGCGCTTGGAAACCCTTGCCGCGCATTGGGGTGTCGAGCAGCTCAAGGCTCATGACGCTTATGAC GATGCGCGGGTGCTGGCCGAGGTGCTGCCGAAGGTGCTGGAGCGCGCCCGCGAGCGTGGCACCTGGCTGCCCATCCGCGA GACCACACGTAAGCGCTGGCCCAACGGCCGCGTTACGCACGATGAGCTGCGTCCACTCAAGACACTGGCGTCGCGCCAGC CGTGCCACTGGCTCAACCCCGGCCCGTATACCGCGGGCCAGCCGCTCGTGCAGGGCATGCGTGTGGCATTGAGCTCGGAG GTCTCGCGCACCCACGAAGAGCTGATCGAGCAGATCATGCAGGCCGGTCTCGCCTACGCCGATGCGGTCGACGAGGACAC CTCGCTGGTGATCTGCAACCAGGAAAACCCAGAGCAGGGCAAGGGTTTCCATGCCCGCTCATTGGGCGTACCGCTGCTCG ATGACCGGACGTTCATGACCGAGGTGCGCCGCGTTGTCGGTGGCACCGATATCGAACAATTCACGGTTCCCAGTCGTGCC GGAGCTCAGTACTCGCTGTTTTGA
Upstream 100 bases:
>100_bases ACGGTCCCACCGAGGTGCACAAGTACGCCATCGGACGCCAGGTGCTTCGGACTCCGCGCGCCTAGGGCGGGTTGTCGGTC CCGCGTGCCATCCTTCAGTC
Downstream 100 bases:
>100_bases TGAGTCCAGCCTGATGCGCCGAATCCTCGCTGTAGTGCTGACGATTGCGCTGCTGGTCAGCGCATGCGGGAAGCACTCGG CGATCGTGGTGGCCGAGCTG
Product: DNA polymerase III subunit epsilon
Products: NA
Alternate protein names: PolIII [H]
Number of amino acids: Translated: 327; Mature: 326
Protein sequence:
>327_residues MPIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPGPTHVHGLTPEMLEGQPEFSD IAPDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTEAVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYD DARVLAEVLPKVLERARERGTWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSE VSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMTEVRRVVGGTDIEQFTVPSRA GAQYSLF
Sequences:
>Translated_327_residues MPIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPGPTHVHGLTPEMLEGQPEFSD IAPDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTEAVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYD DARVLAEVLPKVLERARERGTWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSE VSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMTEVRRVVGGTDIEQFTVPSRA GAQYSLF >Mature_326_residues PIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPGPTHVHGLTPEMLEGQPEFSDI APDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTEAVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYDD ARVLAEVLPKVLERARERGTWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSEV SRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMTEVRRVVGGTDIEQFTVPSRAG AQYSLF
Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]
COG id: COG0847
COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 exonuclease domain [H]
Homologues:
Organism=Escherichia coli, GI1786409, Length=169, Percent_Identity=28.9940828402367, Blast_Score=67, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011708 - InterPro: IPR006054 - InterPro: IPR006055 - InterPro: IPR013520 - InterPro: IPR023223 - InterPro: IPR016027 - InterPro: IPR004013 - InterPro: IPR003141 - InterPro: IPR006308 - InterPro: IPR012337 [H]
Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 36030; Mature: 35899
Theoretical pI: Translated: 4.83; Mature: 4.83
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPG CCCCCCCCCCCCCEEEEEEECCCCCCCHHHHEEHHHHEECCCCCHHHHHHHHHCCCCCCC PTHVHGLTPEMLEGQPEFSDIAPDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTE CCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCHH AVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYDDARVLAEVLPKVLERARERG HHEEHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC TWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSE CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH VSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMT HHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCEEHHHCCCCCCCCHHHHH EVRRVVGGTDIEQFTVPSRAGAQYSLF HHHHHHCCCCCHHEECCCCCCCCCCCC >Mature Secondary Structure PIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPG CCCCCCCCCCCCEEEEEEECCCCCCCHHHHEEHHHHEECCCCCHHHHHHHHHCCCCCCC PTHVHGLTPEMLEGQPEFSDIAPDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTE CCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCHH AVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYDDARVLAEVLPKVLERARERG HHEEHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC TWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSE CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH VSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMT HHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCEEHHHCCCCCCCCHHHHH EVRRVVGGTDIEQFTVPSRAGAQYSLF HHHHHHCCCCCHHEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11997336 [H]