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The map label for this gene is mmgC [H]

Identifier: 169627432

GI number: 169627432

Start: 328365

End: 329546

Strand: Direct

Name: mmgC [H]

Synonym: MAB_0328

Alternate gene names: 169627432

Gene position: 328365-329546 (Clockwise)

Preceding gene: 169627431

Following gene: 169627433

Centisome position: 6.48

GC content: 63.71

Gene sequence:

>1182_bases
ATGATCGACTTCAGCATTCCGGAAGAGCTGGCCGCGAAGGCGCAGCGGGTGCGTGAGTTCGTCACCGAGACCGTGATTCC
GTACGAGCGCGATCCTCGCCTGACCGCGCACGGACCCACCGAGGAGCTGCGCGACGAGTTGGTCGGTAAGGCCAGGGCGG
CCGGTCTGCTGACCGTTCAGGCGCCAGAATCCTATGGTGGGTGGGGTCTTTCGCACATCGGCCAGGCGGTGATCTTCGAG
GCCGCGGGCTGGTCGACCCTGGGGCCCATCGCCATGAACTGTGCGGCACCCGATGAGGGCAACATGTTCCTGCTCGGCAA
GATCACCAACGAGGAACAATCCGAGAAGTTTCTGCGTCCCGTCATCGAGGGGTATCAGCGCTCGGCGTTCGCGATGACCG
AACCCGACGGGGCCGGTTCCGATCCGTCGCAGTTGAAGACCTCGGCGACCTTCGACGGGCAGAATTTCGTCATCAACGGC
CGTAAATGGCTCATCACCGGAGCTCGCGGCGCCAAAACGTGGATCATCATGGCCAACCTGGAGGCCAACGATCACCTGCC
GGAGGGGCCGACACTGTTTCTCTGCGACGGCGAGACCGAAGGCATTGTGATCGAACGCATCATGAACACCATGGACCGCA
ACTACGCCGAGGGGCATGCCGTGGTGCGGTTCGACAATCTCACCCTGCCGCGGGAGGCGTTGCTCGGTGAGACCGGGCAG
GCGTTCCGATACGCGCAGCTGCGGCTGGCCCCGGCCCGGTTGACGCACTGTATGCGCTGGCTCGGTGCCGCCTCCCGGGC
CCAGGACATCGCGGTCGACTATGCGCGAACCCGGACCTCGTTCGGTAAGACGATCGGCGAGCACCAGGGGGTTTCCTTCA
TGCTCGCCGACAACGAGATCGCGTTGCATCAGTGTCGACTGACCATCTGGCATGCCTGCTGGATGATGGACAACGGCGCC
AAGGGCCGGCACGAAAGTTCGATGGCGAAGTCCTTCGTGTCCGAGGAGTTGTTCAAGGTGACCGACCGGTGTGTTCAGGT
GCTCGGCGGCATCGGCATCAGCGATGAGACGCCGGTGGAGATGATCTTCCGTGATATGCGCGCCTTCCGTCTGTACGACG
GTCCCACCGAGGTGCACAAGTACGCCATCGGACGCCAGGTGCTTCGGACTCCGCGCGCCTAG

Upstream 100 bases:

>100_bases
GGCAGTCCGGCGACCTCATCGGACCCGGATACGCAGATTTCGAAAACATTGCCATGTCCGTCCTTGACTGGGCAACAACA
CAATTCACCGAGGGAGAAAT

Downstream 100 bases:

>100_bases
GGCGGGTTGTCGGTCCCGCGTGCCATCCTTCAGTCATGCCGATCTGGGGGCAGACGCCCGACCACAGCCCCAAGTGGGTG
GTGGTTGACCTGGAGACTTC

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQAPESYGGWGLSHIGQAVIFE
AAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVING
RKWLITGARGAKTWIIMANLEANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQ
AFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGA
KGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVEMIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA

Sequences:

>Translated_393_residues
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQAPESYGGWGLSHIGQAVIFE
AAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVING
RKWLITGARGAKTWIIMANLEANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQ
AFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGA
KGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVEMIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA
>Mature_393_residues
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQAPESYGGWGLSHIGQAVIFE
AAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVING
RKWLITGARGAKTWIIMANLEANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQ
AFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGA
KGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVEMIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=32.7543424317618, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=32.7543424317618, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI38505218, Length=391, Percent_Identity=32.7365728900256, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI187960098, Length=392, Percent_Identity=29.3367346938776, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI4557231, Length=392, Percent_Identity=29.3367346938776, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI4557233, Length=395, Percent_Identity=29.1139240506329, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI4501859, Length=380, Percent_Identity=27.3684210526316, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=30.1047120418848, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7656849, Length=367, Percent_Identity=28.0653950953678, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI21361497, Length=398, Percent_Identity=26.6331658291457, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=25.7142857142857, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI226958412, Length=332, Percent_Identity=25.6024096385542, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503943, Length=287, Percent_Identity=27.5261324041812, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7669494, Length=275, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=407, Percent_Identity=27.5184275184275, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=28.7790697674419, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=30.3341902313625, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17562446, Length=405, Percent_Identity=32.3456790123457, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=30.7894736842105, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=31.7333333333333, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=387, Percent_Identity=28.6821705426357, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=27.2, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17538396, Length=384, Percent_Identity=27.8645833333333, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=26.775956284153, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=27.3936170212766, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=27.0341207349081, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71985184, Length=338, Percent_Identity=29.2899408284024, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71990804, Length=297, Percent_Identity=28.6195286195286, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=249, Percent_Identity=28.1124497991968, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=27.1062271062271, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=25.3061224489796, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=23.9074550128535, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=275, Percent_Identity=28, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=29.973474801061, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356377, Length=343, Percent_Identity=30.3206997084548, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24660351, Length=392, Percent_Identity=27.5510204081633, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666513, Length=338, Percent_Identity=30.1775147928994, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355753, Length=340, Percent_Identity=28.8235294117647, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281363737, Length=397, Percent_Identity=26.448362720403, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920834, Length=294, Percent_Identity=26.8707482993197, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43610; Mature: 43610

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCEEEEEE
APESYGGWGLSHIGQAVIFEAAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRP
CCCCCCCCCHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHH
VIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVINGRKWLITGARGAKTWIIMANL
HHHHHCCCEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCEEEEECCCCCEEEEEEEEC
EANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQ
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCC
AFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEI
CEEHHHEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
ALHQCRLTIWHACWMMDNGAKGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVE
EHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA
HHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCEEEEEE
APESYGGWGLSHIGQAVIFEAAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRP
CCCCCCCCCHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHH
VIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVINGRKWLITGARGAKTWIIMANL
HHHHHCCCEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCEEEEECCCCCEEEEEEEEC
EANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQ
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCC
AFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEI
CEEHHHEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
ALHQCRLTIWHACWMMDNGAKGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVE
EHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA
HHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]