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The map label for this gene is ampH [C]

Identifier: 169627434

GI number: 169627434

Start: 330537

End: 331730

Strand: Direct

Name: ampH [C]

Synonym: MAB_0330

Alternate gene names: 169627434

Gene position: 330537-331730 (Clockwise)

Preceding gene: 169627433

Following gene: 169627439

Centisome position: 6.52

GC content: 62.31

Gene sequence:

>1194_bases
GTGCCGGAGCTCAGTACTCGCTGTTTTGATGAGTCCAGCCTGATGCGCCGAATCCTCGCTGTAGTGCTGACGATTGCGCT
GCTGGTCAGCGCATGCGGGAAGCACTCGGCGATCGTGGTGGCCGAGCTGGATCCGCAGACCACGGCCAAGCTGGACTCTG
CCATCAACGAGATACTGACGAGCGCCGCGGTCCCGGGTGCGATCGTCGGAGTATGGGGGCCCAAAGGGCAATACGTGCGG
ACGTTCGGAGTCGCGAACACGGCGACTCGCGCGCCGCTGCGGCCGGACTTCTACCACCGGATCGGCAGTGTGACAAAGAC
CTTCACCGTCACGGCGGTGCTGCAACTTGTCGATGAGGGCAAGGTCGAACTTGACGACCCGATCGCCAAGTATGTCGACA
AGGTCCCGAACGGCAACAAGATCACCCTGCGTGAACTCGCCCGAATGCAGAGCGGACTCTTCAACTATTCGATGTCACTG
GCCTTCAGCCGAGACCTGGAGGCCGATCCTCGCCGCCAGTACAGCACCCATGAGCTGCTCGACTATGCCTTTGCGCAGCC
GTCCAATTTCGTCCCAGGGCAGGGCTACGAGTACAGCAACACCAATGCGGTGCTGCTGGGTCAGGTGGTGGAGAAGGTCA
GCGGGCAGACACTGCCCGCATTCGTCCAAGAGCACATAACCGGTCCACTGGGTATGCGCCGCACCAGCTTTCCGGAGACC
AGTGCCATTGCAGATCCGCACGCGCGGGGTTACACGCAGCTGACACCGACCGGGTCGCTTGTCGACAGCACCGATTGGAA
CCCGTCATGGGCGTCGTGGGCGGGCGCCATGATTTCCACACTCGACGACCTTCGGATCTGGGTGCCCGCGCTGGCGACGG
GCGTGCTCCTGAAGCCCGACAGTCAGCAGCAGCGGCTACAGACTGTGGCGATGCCCCCCGTACCTGACGATATCCGCTAT
GGCTTAGGCATTTTCGACGCGCGGGGCTGGATCGGTCACAGTGGCAGCATTCCGGGCTATCAGACACTTGCCATCTACTC
GCCGGCCGAGCAGACCACGGTGGTGGCCCTGCTCAACACCGATGTGGCCAAGCAACCTGCACAGCCCAGCACACTGTTCG
GCACCGCGATCACCAAAGTGATCAGCCCGGACCATGTCTTTCTGCTGGAAAACGCGATTCCGCAGCCGCGTTGA

Upstream 100 bases:

>100_bases
CGCTCATTGGGCGTACCGCTGCTCGATGACCGGACGTTCATGACCGAGGTGCGCCGCGTTGTCGGTGGCACCGATATCGA
ACAATTCACGGTTCCCAGTC

Downstream 100 bases:

>100_bases
TCAGGCGTAGGGCAGCAGCGCCATCTCTCGCGCGTTCTTGATCGCGTTGGCAACCTGGCGCTGCTGTTGCACCGTCAGGC
CGGTCACCCGGCGGGACCGG

Product: Beta-lactamase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILTSAAVPGAIVGVWGPKGQYVR
TFGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEGKVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSL
AFSRDLEADPRRQYSTHELLDYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPET
SAIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPDSQQQRLQTVAMPPVPDDIRY
GLGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNTDVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR

Sequences:

>Translated_397_residues
MPELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILTSAAVPGAIVGVWGPKGQYVR
TFGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEGKVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSL
AFSRDLEADPRRQYSTHELLDYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPET
SAIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPDSQQQRLQTVAMPPVPDDIRY
GLGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNTDVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR
>Mature_396_residues
PELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILTSAAVPGAIVGVWGPKGQYVRT
FGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEGKVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSLA
FSRDLEADPRRQYSTHELLDYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPETS
AIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPDSQQQRLQTVAMPPVPDDIRYG
LGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNTDVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=306, Percent_Identity=26.1437908496732, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533026, Length=326, Percent_Identity=26.6871165644172, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43092; Mature: 42960

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILT
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
SAAVPGAIVGVWGPKGQYVRTFGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEG
HHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSLAFSRDLEADPRRQYSTHELL
CCEECCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHH
DYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPET
HHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
SAIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPD
CCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
SQQQRLQTVAMPPVPDDIRYGLGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNT
CHHHHHHHHCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECC
DVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR
CHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
PELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILT
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
SAAVPGAIVGVWGPKGQYVRTFGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEG
HHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSLAFSRDLEADPRRQYSTHELL
CCEECCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHH
DYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPET
HHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
SAIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPD
CCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
SQQQRLQTVAMPPVPDDIRYGLGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNT
CHHHHHHHHCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECC
DVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR
CHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]