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The map label for this gene is phbC [H]

Identifier: 161524656

GI number: 161524656

Start: 1633845

End: 1635710

Strand: Direct

Name: phbC [H]

Synonym: Bmul_1483

Alternate gene names: 161524656

Gene position: 1633845-1635710 (Clockwise)

Preceding gene: 161524655

Following gene: 161524657

Centisome position: 47.38

GC content: 65.59

Gene sequence:

>1866_bases
ATGACAGCATCGAAAAATTCGTCGACGTCCGCTGCGGCGGGCACTTCCGCGGGCAATACGGGATTCGGTTCCGCCGCGCA
GCCGATGCAGCAGATGTTCGAAGCTTGGCTGAATGCATGGCGCGATTTTGCCGATCCGGCGCGTGCCGCGACTGCGTCGC
CCGCCGTCAATCCGTTCGCTTCGTTCCAGTTTCCGAAGTCGTTCCCGTTCCAGATGCCGTCGATGCCCGATTTCGGCGCG
ATGGCGTCGCCGTTCGCGGGGCTCACGCTGCCGGTCGCGGCGATTCCGCCCGAGCGCCTGCAGAAGCTGCAGGCCGACTA
TGCGCGCGACTGCGTCGCGCTGATGCAGCAGGCGGCCGCAGCGAAGCTCGAGGCTCCCGAGCTGAAGGATCGGCGCTTCA
GCGGCGACGCATGGAAGGCATCGCCGGCCCATGCATTCGCGGCCGCGTGGTATCTGCTCAATGCACGTTATCTGCAGGAA
CTCGCCGACGCGCTCGAGACCGATCCGAAAACGCGCGAGCGCATCCGTTTCGCCGTGCAGCAGTGGACGGCCGCCGCCGC
GCCGAGCAACTTCCTCGCGCTGAATCCCGATGCGCAGAAGTCGATTCTCGAAACGCAGGGCGAAAGCCTGCGGCAGGGGA
TGATGAACCTGCTGGGCGATCTGCAGCGCGGCAAGATTTCGCAGACCGACGAATCGCAGTTCGTCGTCGGCAAGAACCTC
GGGTGCACGGAAGGCGCGGTCGTCTACGAGAACGACCTGATCCAGCTGATCCAGTACACGCCGAAGACCGCGAAGGTGTT
CGAGCGGCCGCTGCTGATCGTGCCGCCGTGTATCAACAAGTTCTACATCCTCGATCTGCAGCCCGAGAACTCGCTCGTCG
CGCACGCGGTATCGAGCGGCCATCAGGTGTTTCTCGTGTCGTGGCGCAATGCCGATGCGTCGGTCGCGCACAAGACGTGG
GACGACTACATGAACGAAGGGCTGCTCGCCGCGATCGACGCCGTGCAGCAGGTGAGCGGGCGCGAACAGATCAATACGCT
CGGCTTCTGCGTCGGCGGCACGATGCTCGCGACCGCGCTCGCGGTGCTCGCCGCGCGCGGCGAACATCCGGCCGCGTCGA
TGACGCTGCTTACCGCGATGCTCGACTTCTCCGATACGGGCGTGCTCGACGTGTTCGTCGACGAGGCGCACGTGCAGATG
CGCGAGCAGACGATCGGCGGCAAGAACGGGACGCCGCCCGGGTTGATGCGCGGCGTCGAGTTCGCGAACACGTTCTCGTT
CCTGCGCCCGAACGATCTCGTCTGGAACTACGTCGTCGACAACTACCTGAAGGGCCGCACGCCCGCGCCGTTCGACCTGC
TGTACTGGAACAGCGATTCGACGAGCCTGCCGGGGCCGATGTACGCGTGGTACCTGCGCAATACGTATCTCGAGAACAAG
CTGCGCGAGCCGGGCGCGCTGACCGTCTGCGGCGAGCCGGTCGATCTGTCGCGCATCGACGTGCCGACCTTCATCTACGG
GTCGCGCGAGGATCACATCGTGCCGTGGCAGACGGCCTATGCGTCGACATCGATCCTGACGGGCCCGCTGAAGTTCGTGC
TCGGCGCCTCGGGCCACATCGCCGGCGTGATCAATCCACCCGCGAAGAAAAAGCGCAGCTACTGGGTCAACGACGACGAC
CTGCCGAGCGCCGCCGACGACTGGTTCGCCGGCGCGACCGAGCATCCGGGCAGCTGGTGGACGACCTGGATCGAATGGCT
CGACCAGTACGGCGGCCGCAAGGTGGCGGCGCCAGCCGAGCTCGGCTCCGCGCAATTCCCGGTGATCGAACCGGCACCCG
GCCGTTACGTATTGCAGCGCGATTGA

Upstream 100 bases:

>100_bases
AGACGCCTCTCCAGGGCATGACGGCCCGGCTCGCAGCCGGCATGCCGCGCGCGAGCAGGATTTCGCGATTGACGCTCACG
AATCACCGGTAAGGCAGGTA

Downstream 100 bases:

>100_bases
CGAAAGCCGGACAGCGGCGCACGCTGTCCGACTGCACCGCAGTTTTTTTAACAGGGTCGGCAGCGACGCGCCGTGTCGCG
CGGGCTCGGAGGAATGGAAA

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTASKNSSTSAAAGTSAGNTGFGSAAQPMQQMFEAWLNAWRDFADPARAATASPAVNPFASFQFPKSFPFQMPSMPDFGA
MASPFAGLTLPVAAIPPERLQKLQADYARDCVALMQQAAAAKLEAPELKDRRFSGDAWKASPAHAFAAAWYLLNARYLQE
LADALETDPKTRERIRFAVQQWTAAAAPSNFLALNPDAQKSILETQGESLRQGMMNLLGDLQRGKISQTDESQFVVGKNL
GCTEGAVVYENDLIQLIQYTPKTAKVFERPLLIVPPCINKFYILDLQPENSLVAHAVSSGHQVFLVSWRNADASVAHKTW
DDYMNEGLLAAIDAVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTAMLDFSDTGVLDVFVDEAHVQM
REQTIGGKNGTPPGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNSDSTSLPGPMYAWYLRNTYLENK
LREPGALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYASTSILTGPLKFVLGASGHIAGVINPPAKKKRSYWVNDDD
LPSAADDWFAGATEHPGSWWTTWIEWLDQYGGRKVAAPAELGSAQFPVIEPAPGRYVLQRD

Sequences:

>Translated_621_residues
MTASKNSSTSAAAGTSAGNTGFGSAAQPMQQMFEAWLNAWRDFADPARAATASPAVNPFASFQFPKSFPFQMPSMPDFGA
MASPFAGLTLPVAAIPPERLQKLQADYARDCVALMQQAAAAKLEAPELKDRRFSGDAWKASPAHAFAAAWYLLNARYLQE
LADALETDPKTRERIRFAVQQWTAAAAPSNFLALNPDAQKSILETQGESLRQGMMNLLGDLQRGKISQTDESQFVVGKNL
GCTEGAVVYENDLIQLIQYTPKTAKVFERPLLIVPPCINKFYILDLQPENSLVAHAVSSGHQVFLVSWRNADASVAHKTW
DDYMNEGLLAAIDAVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTAMLDFSDTGVLDVFVDEAHVQM
REQTIGGKNGTPPGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNSDSTSLPGPMYAWYLRNTYLENK
LREPGALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYASTSILTGPLKFVLGASGHIAGVINPPAKKKRSYWVNDDD
LPSAADDWFAGATEHPGSWWTTWIEWLDQYGGRKVAAPAELGSAQFPVIEPAPGRYVLQRD
>Mature_620_residues
TASKNSSTSAAAGTSAGNTGFGSAAQPMQQMFEAWLNAWRDFADPARAATASPAVNPFASFQFPKSFPFQMPSMPDFGAM
ASPFAGLTLPVAAIPPERLQKLQADYARDCVALMQQAAAAKLEAPELKDRRFSGDAWKASPAHAFAAAWYLLNARYLQEL
ADALETDPKTRERIRFAVQQWTAAAAPSNFLALNPDAQKSILETQGESLRQGMMNLLGDLQRGKISQTDESQFVVGKNLG
CTEGAVVYENDLIQLIQYTPKTAKVFERPLLIVPPCINKFYILDLQPENSLVAHAVSSGHQVFLVSWRNADASVAHKTWD
DYMNEGLLAAIDAVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTAMLDFSDTGVLDVFVDEAHVQMR
EQTIGGKNGTPPGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNSDSTSLPGPMYAWYLRNTYLENKL
REPGALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYASTSILTGPLKFVLGASGHIAGVINPPAKKKRSYWVNDDDL
PSAADDWFAGATEHPGSWWTTWIEWLDQYGGRKVAAPAELGSAQFPVIEPAPGRYVLQRD

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 67915; Mature: 67784

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASKNSSTSAAAGTSAGNTGFGSAAQPMQQMFEAWLNAWRDFADPARAATASPAVNPFA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHH
SFQFPKSFPFQMPSMPDFGAMASPFAGLTLPVAAIPPERLQKLQADYARDCVALMQQAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AKLEAPELKDRRFSGDAWKASPAHAFAAAWYLLNARYLQELADALETDPKTRERIRFAVQ
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QWTAAAAPSNFLALNPDAQKSILETQGESLRQGMMNLLGDLQRGKISQTDESQFVVGKNL
HHHHHCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GCTEGAVVYENDLIQLIQYTPKTAKVFERPLLIVPPCINKFYILDLQPENSLVAHAVSSG
CCCCCCEEEHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHCCC
HQVFLVSWRNADASVAHKTWDDYMNEGLLAAIDAVQQVSGREQINTLGFCVGGTMLATAL
CEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AVLAARGEHPAASMTLLTAMLDFSDTGVLDVFVDEAHVQMREQTIGGKNGTPPGLMRGVE
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHH
FANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNSDSTSLPGPMYAWYLRNTYLENK
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LREPGALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYASTSILTGPLKFVLGASGHI
CCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCE
AGVINPPAKKKRSYWVNDDDLPSAADDWFAGATEHPGSWWTTWIEWLDQYGGRKVAAPAE
EEEECCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHH
LGSAQFPVIEPAPGRYVLQRD
CCCCCCCEECCCCCCEEEECC
>Mature Secondary Structure 
TASKNSSTSAAAGTSAGNTGFGSAAQPMQQMFEAWLNAWRDFADPARAATASPAVNPFA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHH
SFQFPKSFPFQMPSMPDFGAMASPFAGLTLPVAAIPPERLQKLQADYARDCVALMQQAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AKLEAPELKDRRFSGDAWKASPAHAFAAAWYLLNARYLQELADALETDPKTRERIRFAVQ
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QWTAAAAPSNFLALNPDAQKSILETQGESLRQGMMNLLGDLQRGKISQTDESQFVVGKNL
HHHHHCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GCTEGAVVYENDLIQLIQYTPKTAKVFERPLLIVPPCINKFYILDLQPENSLVAHAVSSG
CCCCCCEEEHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHCCC
HQVFLVSWRNADASVAHKTWDDYMNEGLLAAIDAVQQVSGREQINTLGFCVGGTMLATAL
CEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AVLAARGEHPAASMTLLTAMLDFSDTGVLDVFVDEAHVQMREQTIGGKNGTPPGLMRGVE
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHH
FANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNSDSTSLPGPMYAWYLRNTYLENK
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LREPGALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYASTSILTGPLKFVLGASGHI
CCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCE
AGVINPPAKKKRSYWVNDDDLPSAADDWFAGATEHPGSWWTTWIEWLDQYGGRKVAAPAE
EEEECCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHH
LGSAQFPVIEPAPGRYVLQRD
CCCCCCCEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]