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The map label for this gene is menC [H]

Identifier: 160877392

GI number: 160877392

Start: 5070309

End: 5071409

Strand: Direct

Name: menC [H]

Synonym: Sbal195_4290

Alternate gene names: 160877392

Gene position: 5070309-5071409 (Clockwise)

Preceding gene: 160877391

Following gene: 160877393

Centisome position: 94.82

GC content: 48.41

Gene sequence:

>1101_bases
ATGATCTTAACTTCGCTTAACCTGTATCAATATCGACTACCGCTCGATGTATTATTGCCCGTAGGCAAGCAACGCATCGA
CCACAGGGCTGGATTAGTATTGCAAGCCTGCGCCAGCGCTAATGTTGGTGGCGAATACAGACAAGTCGAAGTTGAAATCG
CCCCACTCTCTGGCATAGATATCGATGAACAAGTCTTAGTGGGATTTAGCCGCGAAACACTGGCTCAAGTGCAAACGGCG
TTAACTGAGTTATTACCCCTACTCTGCGGTCTGCATATCGATACCCTGCTGGATTACGCCGAGCAAAGTCCTTACCCTTC
CTTGGCCTTTGGTTTAAGTCTGTTGCATGCCAAGTTAATGGGTAAGCTCGATGCTATCCGCCCACAAACCGCCACAGTCC
CTTTGATTTATCATCCAACGGATGCGGGCAAAGACTTGCTCGATAACAAAGTTGCGGCGCTCGGCATGCATGTTCATTCG
GTGAAAGTTAAAGTCGCGCAGACCTCAATCGAAGACGAACTGAGCCTGATTTATGGCATTTTACGCACCCGCCCTGATCT
CAAGCTACGTTTAGACGCAAACCGAGGGTTTACACTGGAACAAGCGATCGAATTCGCTGCTTGCCTACCCCTGGACACCA
TCGAATACATAGAGGAACCTTGCCAGAATCCACAGGATAATCTGGCATTTTATCAAGCAATTGGTATGCCTTACGCCCTC
GATGAATCACTCAACGATCCCGATTATCAGTTTGCGATGCAAAATGGCCTGACTGCGCTCATCATCAAACCTATGCTGCT
CGGCAGTATTGAAAAGCTAGCTAACTTAATCGATACGGCGCAAAGCTATGGTGTGCGTTGCATTATCAGTTCAAGTCTTG
AAAGCAGTTTAGGCATTAGCGATCTGGCCCATTTAGCCGCGATTCTCACGCCCGATGAAATCCCAGGACTCGATACCCTC
AGCGCCTTTAGCCAAGATTTAATCGTGTCATCGGGTAAAAAACACTGCCTCACACTCGCCCAACTTGAACTCATTGCACA
ACACGCCATTGATTCAACGCAGCAAAGTGATTTGGGTGCAGCCAAGCGTGAGGAAAACTAG

Upstream 100 bases:

>100_bases
CGGCGCCGGACACAACATACACCAAGCAGCTCCCGAGGCATTAATCGCAACAATAGTTAAGCTGCTAGGGTAAACAACAC
AATTAAAATGTAGGAAATAT

Downstream 100 bases:

>100_bases
TTTGTCTGACACCCGCCTATCGCAGTCGCTAGCACTGTCCCCCGTGCACCAAGCCGCGCTGGCGTTTCCACAGCAGACGG
CCAGCAAGTTGGCGGGACAA

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MILTSLNLYQYRLPLDVLLPVGKQRIDHRAGLVLQACASANVGGEYRQVEVEIAPLSGIDIDEQVLVGFSRETLAQVQTA
LTELLPLLCGLHIDTLLDYAEQSPYPSLAFGLSLLHAKLMGKLDAIRPQTATVPLIYHPTDAGKDLLDNKVAALGMHVHS
VKVKVAQTSIEDELSLIYGILRTRPDLKLRLDANRGFTLEQAIEFAACLPLDTIEYIEEPCQNPQDNLAFYQAIGMPYAL
DESLNDPDYQFAMQNGLTALIIKPMLLGSIEKLANLIDTAQSYGVRCIISSSLESSLGISDLAHLAAILTPDEIPGLDTL
SAFSQDLIVSSGKKHCLTLAQLELIAQHAIDSTQQSDLGAAKREEN

Sequences:

>Translated_366_residues
MILTSLNLYQYRLPLDVLLPVGKQRIDHRAGLVLQACASANVGGEYRQVEVEIAPLSGIDIDEQVLVGFSRETLAQVQTA
LTELLPLLCGLHIDTLLDYAEQSPYPSLAFGLSLLHAKLMGKLDAIRPQTATVPLIYHPTDAGKDLLDNKVAALGMHVHS
VKVKVAQTSIEDELSLIYGILRTRPDLKLRLDANRGFTLEQAIEFAACLPLDTIEYIEEPCQNPQDNLAFYQAIGMPYAL
DESLNDPDYQFAMQNGLTALIIKPMLLGSIEKLANLIDTAQSYGVRCIISSSLESSLGISDLAHLAAILTPDEIPGLDTL
SAFSQDLIVSSGKKHCLTLAQLELIAQHAIDSTQQSDLGAAKREEN
>Mature_366_residues
MILTSLNLYQYRLPLDVLLPVGKQRIDHRAGLVLQACASANVGGEYRQVEVEIAPLSGIDIDEQVLVGFSRETLAQVQTA
LTELLPLLCGLHIDTLLDYAEQSPYPSLAFGLSLLHAKLMGKLDAIRPQTATVPLIYHPTDAGKDLLDNKVAALGMHVHS
VKVKVAQTSIEDELSLIYGILRTRPDLKLRLDANRGFTLEQAIEFAACLPLDTIEYIEEPCQNPQDNLAFYQAIGMPYAL
DESLNDPDYQFAMQNGLTALIIKPMLLGSIEKLANLIDTAQSYGVRCIISSSLESSLGISDLAHLAAILTPDEIPGLDTL
SAFSQDLIVSSGKKHCLTLAQLELIAQHAIDSTQQSDLGAAKREEN

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=324, Percent_Identity=35.8024691358025, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39881; Mature: 39881

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTSLNLYQYRLPLDVLLPVGKQRIDHRAGLVLQACASANVGGEYRQVEVEIAPLSGID
CEEECCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCC
IDEQVLVGFSRETLAQVQTALTELLPLLCGLHIDTLLDYAEQSPYPSLAFGLSLLHAKLM
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GKLDAIRPQTATVPLIYHPTDAGKDLLDNKVAALGMHVHSVKVKVAQTSIEDELSLIYGI
HHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHH
LRTRPDLKLRLDANRGFTLEQAIEFAACLPLDTIEYIEEPCQNPQDNLAFYQAIGMPYAL
HHCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEC
DESLNDPDYQFAMQNGLTALIIKPMLLGSIEKLANLIDTAQSYGVRCIISSSLESSLGIS
CCCCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHCCHH
DLAHLAAILTPDEIPGLDTLSAFSQDLIVSSGKKHCLTLAQLELIAQHAIDSTQQSDLGA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCC
AKREEN
CCCCCC
>Mature Secondary Structure
MILTSLNLYQYRLPLDVLLPVGKQRIDHRAGLVLQACASANVGGEYRQVEVEIAPLSGID
CEEECCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCC
IDEQVLVGFSRETLAQVQTALTELLPLLCGLHIDTLLDYAEQSPYPSLAFGLSLLHAKLM
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GKLDAIRPQTATVPLIYHPTDAGKDLLDNKVAALGMHVHSVKVKVAQTSIEDELSLIYGI
HHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHH
LRTRPDLKLRLDANRGFTLEQAIEFAACLPLDTIEYIEEPCQNPQDNLAFYQAIGMPYAL
HHCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEC
DESLNDPDYQFAMQNGLTALIIKPMLLGSIEKLANLIDTAQSYGVRCIISSSLESSLGIS
CCCCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHCCHH
DLAHLAAILTPDEIPGLDTLSAFSQDLIVSSGKKHCLTLAQLELIAQHAIDSTQQSDLGA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCC
AKREEN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]