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The map label for this gene is yrfF [C]

Identifier: 157372845

GI number: 157372845

Start: 5088503

End: 5090635

Strand: Direct

Name: yrfF [C]

Synonym: Spro_4613

Alternate gene names: 157372845

Gene position: 5088503-5090635 (Clockwise)

Preceding gene: 157372843

Following gene: 157372846

Centisome position: 93.39

GC content: 57.85

Gene sequence:

>2133_bases
ATGAGCACAATAGTGTTGATATTGGCCTTAGTGCTTGCCTGCCTGATTGCCGCCGGCCTGTATCTTTGGTTCAAAGCCCG
CAATCAGCCGCTGCTGATGCGTACGCTGCCCTTTATCAAACCCACCCACCGCAAGCTGACCGGCGAAGAACGCGCCGCCG
TTGAGCACTATCTTGGCCAACAAAACAAGCTGAGCAACAAACTGTTGCCCGGCAGCAACTCATTGCCTTCTGCCAAACTG
GCGCTGACGCCGCAAAGCGACAACGTCTACCCGGTTACCCACGCCATTACCCGCTACGGTCTGGCCAGCGATGAACCCAA
TAAATGGCGCTATTATCTGGACGCCGAAGAGGTGCATCTGCCGCCGTTCTGGGAGCAGTACATCAGCGCCGATAACCATG
TGGAAGTGATTAGAACCCAGACGTTGCCGCTGGTGATCTCTCTCAACGGGCATTCGCTGAAAGACCATATTCACGATCGG
CCGCTGCCGCCAGTGGTGAAGGCGACCCCGAGCCAAAATGCCTCTATCCGCAAGGAAGAGAGCGAGCATGTCGAACTGCT
GAACATCCGCAAGGAAAGCCCGGAAGAACACGCACTCAATCGCCCGAACGGTATCAAAGAGGCCGCCATTATCTCGGCGG
CTCTGCTGCTGCTGTTCTTCAGCCTGATAAGCCCGGTCGTGGTGATCCCCTGGATGATTGTCGTCGCCGTGTTGATGATC
GCCTGGGGCTGCTGGAACCTGTTCCGCCGCCCTGCCACACGCGAACTAAAAGAAGTGCACTGCCTGCGGGGTACCCCCAA
GCGCTGGGGGCTGTTTGGCGAATCCAACCAGGGGCAAATCAGCAATATTTCACTCGGCATCATTGACCTGATTTATCCGC
CGCACTGGCAGCCATACATCGCTCAGGATCTGGGTAAAACCACCGACGTGGATATCTACCTTAACCGCCAGGTGCTGCGC
CAGGGTCGCTACCTTTCGCTGCATGATGAGGTGAAAAACTTCCCGCTGCAGCAATGGGGCAGGAACGCGGTTCTCATGGC
CAGTTCACTTTTGGTACTGCTGCTGTTGCTGACCTATATCCCGCTCAGCCTGCCGCTCAAGCTGAGCATGGCCTGGCTAC
AGGGCGCGCAAAAAATTGAAGTGACCAACGTACAGGCACTGGAAGGCGCAACGTTACGCATCGGGGATACCCTGAAAGCC
CAGGGCACGGGCATGTGCTACGTACCACCGTTAACCAGTGGCACGCGCTCCGCCAGCTTTATGCCGTTCGACTGTTCCGG
AATTTACTGGAACAACGCGGCGCCTCTGCCGCAGCCGGAGTCGGAAGTGATCGACAAGGCCTCAGCCCTGCTGGCGACGG
TCAACACCCAGTTGCACCCTGACGGCTCCGACCAAAAGCTCAACCCACAGTTGGCCAGCGCAATCGAAAAATCCGGCATG
ATCCTGCTGGATGATTTTTCCGATATCGTGCTGAAAACGCAGGATCTGTGCCAAGCGGATAATGACTGCGTCCGGCTGAA
GAACGCACTGGTCAATCTGGGCAACGTCAAAAATTGGGGCACCCTGGTGAAACGTGCCAAATCAGGCTCGCTGCAAGGGG
TGAACGTGTTGCTGCGCCCGGTGAGCGCCGAATCGCTGGAGAGCCTGACCAAAGTGGCCGCATCATCCTTCGTCTACAGC
GAAACCAGGCAGGCCGCCGCCGCGCTCAACAGCCCGCCACCGGGGGGGTTCCTGATCACCAGTGATGAAGGCAAACAGCT
GGTGAATCATCCGCAGCCGACGGTGCCGCTAAACGAATACAACGCACTTGACCAGTGGAATGAGCTACAACGCCTTGCCG
GCATGCTGCTGCATACGCCGTTCGAGGCCCAGGGCGTGATCACCAATATCAGCGTCGATGCCAACGGTACCCGTCATATT
GCACTGCACAGCGAACCGGATATCATCACCCTGTGGCGCTATCTCGGCACCAGCCTGCTGCTGCTGAGCGTCGCCGTCGT
GCTGGGCTACAACAGCTGGAAACTGGTGCAGCGCCGTTGCATCAATCAGCACCGCATCGCTGATATCCAGCGCTACTACG
AAAGCTGCTTTAACCCGCAGCTCGCCCCGATGTCATTGCGCCCGATGCCCTGA

Upstream 100 bases:

>100_bases
CTCTCGTTACGGATCAGGGTGTCTCTTGGTGATTTGGCTGCGTATAATAGTCCAGGATTCATCAGGTTGGTGAGGTTCAC
GGGTACAGGATGGGGATAGC

Downstream 100 bases:

>100_bases
GCCACTAGCCCCGGCCTGCGCCCTGTCATCAGCTTATGCTACGCTAACGCTATTCCCCTTATCCTGCGGACCGCCGAAGG
TTCGCCTATGGAGTTTTCAT

Product: intracellular growth attenuator IgaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSTIVLILALVLACLIAAGLYLWFKARNQPLLMRTLPFIKPTHRKLTGEERAAVEHYLGQQNKLSNKLLPGSNSLPSAKL
ALTPQSDNVYPVTHAITRYGLASDEPNKWRYYLDAEEVHLPPFWEQYISADNHVEVIRTQTLPLVISLNGHSLKDHIHDR
PLPPVVKATPSQNASIRKEESEHVELLNIRKESPEEHALNRPNGIKEAAIISAALLLLFFSLISPVVVIPWMIVVAVLMI
AWGCWNLFRRPATRELKEVHCLRGTPKRWGLFGESNQGQISNISLGIIDLIYPPHWQPYIAQDLGKTTDVDIYLNRQVLR
QGRYLSLHDEVKNFPLQQWGRNAVLMASSLLVLLLLLTYIPLSLPLKLSMAWLQGAQKIEVTNVQALEGATLRIGDTLKA
QGTGMCYVPPLTSGTRSASFMPFDCSGIYWNNAAPLPQPESEVIDKASALLATVNTQLHPDGSDQKLNPQLASAIEKSGM
ILLDDFSDIVLKTQDLCQADNDCVRLKNALVNLGNVKNWGTLVKRAKSGSLQGVNVLLRPVSAESLESLTKVAASSFVYS
ETRQAAAALNSPPPGGFLITSDEGKQLVNHPQPTVPLNEYNALDQWNELQRLAGMLLHTPFEAQGVITNISVDANGTRHI
ALHSEPDIITLWRYLGTSLLLLSVAVVLGYNSWKLVQRRCINQHRIADIQRYYESCFNPQLAPMSLRPMP

Sequences:

>Translated_710_residues
MSTIVLILALVLACLIAAGLYLWFKARNQPLLMRTLPFIKPTHRKLTGEERAAVEHYLGQQNKLSNKLLPGSNSLPSAKL
ALTPQSDNVYPVTHAITRYGLASDEPNKWRYYLDAEEVHLPPFWEQYISADNHVEVIRTQTLPLVISLNGHSLKDHIHDR
PLPPVVKATPSQNASIRKEESEHVELLNIRKESPEEHALNRPNGIKEAAIISAALLLLFFSLISPVVVIPWMIVVAVLMI
AWGCWNLFRRPATRELKEVHCLRGTPKRWGLFGESNQGQISNISLGIIDLIYPPHWQPYIAQDLGKTTDVDIYLNRQVLR
QGRYLSLHDEVKNFPLQQWGRNAVLMASSLLVLLLLLTYIPLSLPLKLSMAWLQGAQKIEVTNVQALEGATLRIGDTLKA
QGTGMCYVPPLTSGTRSASFMPFDCSGIYWNNAAPLPQPESEVIDKASALLATVNTQLHPDGSDQKLNPQLASAIEKSGM
ILLDDFSDIVLKTQDLCQADNDCVRLKNALVNLGNVKNWGTLVKRAKSGSLQGVNVLLRPVSAESLESLTKVAASSFVYS
ETRQAAAALNSPPPGGFLITSDEGKQLVNHPQPTVPLNEYNALDQWNELQRLAGMLLHTPFEAQGVITNISVDANGTRHI
ALHSEPDIITLWRYLGTSLLLLSVAVVLGYNSWKLVQRRCINQHRIADIQRYYESCFNPQLAPMSLRPMP
>Mature_709_residues
STIVLILALVLACLIAAGLYLWFKARNQPLLMRTLPFIKPTHRKLTGEERAAVEHYLGQQNKLSNKLLPGSNSLPSAKLA
LTPQSDNVYPVTHAITRYGLASDEPNKWRYYLDAEEVHLPPFWEQYISADNHVEVIRTQTLPLVISLNGHSLKDHIHDRP
LPPVVKATPSQNASIRKEESEHVELLNIRKESPEEHALNRPNGIKEAAIISAALLLLFFSLISPVVVIPWMIVVAVLMIA
WGCWNLFRRPATRELKEVHCLRGTPKRWGLFGESNQGQISNISLGIIDLIYPPHWQPYIAQDLGKTTDVDIYLNRQVLRQ
GRYLSLHDEVKNFPLQQWGRNAVLMASSLLVLLLLLTYIPLSLPLKLSMAWLQGAQKIEVTNVQALEGATLRIGDTLKAQ
GTGMCYVPPLTSGTRSASFMPFDCSGIYWNNAAPLPQPESEVIDKASALLATVNTQLHPDGSDQKLNPQLASAIEKSGMI
LLDDFSDIVLKTQDLCQADNDCVRLKNALVNLGNVKNWGTLVKRAKSGSLQGVNVLLRPVSAESLESLTKVAASSFVYSE
TRQAAAALNSPPPGGFLITSDEGKQLVNHPQPTVPLNEYNALDQWNELQRLAGMLLHTPFEAQGVITNISVDANGTRHIA
LHSEPDIITLWRYLGTSLLLLSVAVVLGYNSWKLVQRRCINQHRIADIQRYYESCFNPQLAPMSLRPMP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the igaA family [H]

Homologues:

Organism=Escherichia coli, GI1789801, Length=712, Percent_Identity=57.0224719101124, Blast_Score=760, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010771
- ProDom:   PD147088 [H]

Pfam domain/function: PF07095 IgaA [H]

EC number: NA

Molecular weight: Translated: 78964; Mature: 78833

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIVLILALVLACLIAAGLYLWFKARNQPLLMRTLPFIKPTHRKLTGEERAAVEHYLGQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCHHHCCCHHHHHHHHHHCC
QNKLSNKLLPGSNSLPSAKLALTPQSDNVYPVTHAITRYGLASDEPNKWRYYLDAEEVHL
CHHHCCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
PPFWEQYISADNHVEVIRTQTLPLVISLNGHSLKDHIHDRPLPPVVKATPSQNASIRKEE
CHHHHHHCCCCCCEEEEEECCEEEEEEECCCCHHHHHCCCCCCCCEECCCCCCCCCCCCC
SEHVELLNIRKESPEEHALNRPNGIKEAAIISAALLLLFFSLISPVVVIPWMIVVAVLMI
HHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWGCWNLFRRPATRELKEVHCLRGTPKRWGLFGESNQGQISNISLGIIDLIYPPHWQPYI
HHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHH
AQDLGKTTDVDIYLNRQVLRQGRYLSLHDEVKNFPLQQWGRNAVLMASSLLVLLLLLTYI
HHHCCCCCCEEEEECHHHHHCCCEEEEHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHC
PLSLPLKLSMAWLQGAQKIEVTNVQALEGATLRIGDTLKAQGTGMCYVPPLTSGTRSASF
CCCCCHHHHHHHHCCCCEEEEECEEEECCCEEEECCCEECCCCCEEEECCCCCCCCCCCC
MPFDCSGIYWNNAAPLPQPESEVIDKASALLATVNTQLHPDGSDQKLNPQLASAIEKSGM
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHCCC
ILLDDFSDIVLKTQDLCQADNDCVRLKNALVNLGNVKNWGTLVKRAKSGSLQGVNVLLRP
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEC
VSAESLESLTKVAASSFVYSETRQAAAALNSPPPGGFLITSDEGKQLVNHPQPTVPLNEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCC
NALDQWNELQRLAGMLLHTPFEAQGVITNISVDANGTRHIALHSEPDIITLWRYLGTSLL
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHH
LLSVAVVLGYNSWKLVQRRCINQHRIADIQRYYESCFNPQLAPMSLRPMP
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
STIVLILALVLACLIAAGLYLWFKARNQPLLMRTLPFIKPTHRKLTGEERAAVEHYLGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCHHHCCCHHHHHHHHHHCC
QNKLSNKLLPGSNSLPSAKLALTPQSDNVYPVTHAITRYGLASDEPNKWRYYLDAEEVHL
CHHHCCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
PPFWEQYISADNHVEVIRTQTLPLVISLNGHSLKDHIHDRPLPPVVKATPSQNASIRKEE
CHHHHHHCCCCCCEEEEEECCEEEEEEECCCCHHHHHCCCCCCCCEECCCCCCCCCCCCC
SEHVELLNIRKESPEEHALNRPNGIKEAAIISAALLLLFFSLISPVVVIPWMIVVAVLMI
HHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWGCWNLFRRPATRELKEVHCLRGTPKRWGLFGESNQGQISNISLGIIDLIYPPHWQPYI
HHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHH
AQDLGKTTDVDIYLNRQVLRQGRYLSLHDEVKNFPLQQWGRNAVLMASSLLVLLLLLTYI
HHHCCCCCCEEEEECHHHHHCCCEEEEHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHC
PLSLPLKLSMAWLQGAQKIEVTNVQALEGATLRIGDTLKAQGTGMCYVPPLTSGTRSASF
CCCCCHHHHHHHHCCCCEEEEECEEEECCCEEEECCCEECCCCCEEEECCCCCCCCCCCC
MPFDCSGIYWNNAAPLPQPESEVIDKASALLATVNTQLHPDGSDQKLNPQLASAIEKSGM
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHCCC
ILLDDFSDIVLKTQDLCQADNDCVRLKNALVNLGNVKNWGTLVKRAKSGSLQGVNVLLRP
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEC
VSAESLESLTKVAASSFVYSETRQAAAALNSPPPGGFLITSDEGKQLVNHPQPTVPLNEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCC
NALDQWNELQRLAGMLLHTPFEAQGVITNISVDANGTRHIALHSEPDIITLWRYLGTSLL
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHH
LLSVAVVLGYNSWKLVQRRCINQHRIADIQRYYESCFNPQLAPMSLRPMP
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]