| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is mrcA [H]
Identifier: 157372843
GI number: 157372843
Start: 5084873
End: 5087431
Strand: Direct
Name: mrcA [H]
Synonym: Spro_4611
Alternate gene names: 157372843
Gene position: 5084873-5087431 (Clockwise)
Preceding gene: 157372830
Following gene: 157372845
Centisome position: 93.32
GC content: 56.98
Gene sequence:
>2559_bases GTGAAGTTCGTAAAGTATTTACTAATCCTTGCAGTGTGTTGCATCGTGTTGGGGGCAGCCTCGATTTTTGGCTTGTACAA ATATGTCGAGCCACAGCTGCCTGACGTCGCAACGCTGAAAGATGTGCGGCTGCAAATACCGATGCAGGTTTACAGCGCCG ACGGCGAGCTGATCGCCCAATACGGTGAGAAACGCCGTATTCCGCTAAAATTGAACCAAATTCCGCCGGTTATGGTGCAT GCGTTTATCGCCACCGAAGACAGCCGCTTCTATGAGCATCATGGCGTCGACCCAATCGGTATCTTCCGTGCTGCCTCTAT TGCGCTGGTCTCTGGCCATGCGTCACAGGGGGCAAGTACCATTACCCAGCAGCTGGCGAGAAACTTCTTCTTAAGCCCGG AACGCACCCTGATGCGCAAGATCAAGGAAGCCTTCCTGGCAATACGCATCGAGCAGATGCTGACCAAAGACGAAATCCTC GAGCTGTATCTGAACAAAATCTATCTGGGGTATCGCGCCTATGGCGTGGGTGCCGCGGCGCAGGTTTACTTCGGTAAAGA CGTCAGTCAGCTCAGCTTAAGCGAAATGGCGACCATCGCCGGCTTGCCGAAAGCTCCATCAACCTTCAATCCGCTCTACT CTCACGATCGCGCCGTAGCTCGCCGCAACGTGGTGCTGTCGCGCATGCTGGATGAGCATTACATCACTCAGGCGCAGTTC GACCAGGCGCGCAGTGAAGAGTTGGTGGCCAATTACCATGCGCCAGAAATCAGCTTCTCTGCACCCTATCTCTCCGAAAT GGTGCGTCAGGAGATGATCAAGCGTTACGGTGACAATGCTTATACCGACGGCTACAAGGTCTACACCACCGTCACCAAAA AACTGCAGTTGGCGGCGCAGGACTCAGTGCGTAACAACGTGCTGGCGTACGATATGCGCCACGGCTACCGCGGCCCGTCC AACGTGCTGTGGAAAGTAGGTGAAGCGGCCTGGGACCAAAAGCAGATCGTCGATTCCTTGAAGAATCTGCCGAACTACGG CCCATTGTCGCCGGCGGTGATTGTTTCAACCAGCGCCGAAGAGGCAACGGCCATGATGGCAGACGGTAGCCATGTGGCGC TGCCAATGTCCACCATGCGCTGGGCACGACCTTATAGATCCGACACTCAGCAAGGCCCAACGCCGAAACGCGTCACCGAT GTGGTGCAGGCCGGCCAACAAGTGTGGGTTCGCAAGGTGGGTGAAAACTGGTGGCTGTCACAGGTGCCGGACGTCAACTC CGCCCTGGTTTCGATCAACCCGAATGACGGCGCGGTGAAAGCCCTGGTCGGCGGGTTTGACTTCAACCAAAGCAAGTTCA ACCGCGTGACTCAGGCGCTGCGTCAGGTCGGCTCCAATATCAAGCCCTTCCTGTATACCGCCGCGATGGACAAGGGCCTG ACCCTGGCCACTATCCTCAATGACCTGCCGATCACCCGTTGGGATGCAGGTGCCGGTACCGACTGGCGGCCGAAGAACTC ACCGCCAACTTACGATGGCCCGATTCGCCTGCGTCAGGGGCTAGGACAATCGAAGAACGTGGTGATGGTGCGCGCGATGC GTGCTATGGGCGTCGACTACGCAGCGGAATACCTGCAGCGTTTCGGCTTCCCGGCGCAAAACATCGTGCATACCGAATCA CTGGCACTGGGCTCGGCTTCGTTCACCCCAATGCAGCTGGTACGCGGTTACGCGGTGCTGGCTAACGGCGGTTATCTGGT GGATCCGTACTTCATCACCAAGATTGAAGACGATAACGGCAACACCGTGTTCGAAACCAAACCGAAGATTGTCTGCGACA GCTGTAATCTGCCGGTGATTTATGGTGATACTCACCGCTCGGCCGTGCTTTCCGAAGACAACATTGAAAATGTCGCGACG TCGCAGGAAGGCAAAAATGGCAACGTGCCAATGCCGCAGTTAGAGCAGGTGACCCCCGCTCAGGTTCAGCAAGATGGCGA TCAACAGTATGCGCCGCACGTTATCAGCACCCCGCTGGCGTTCCTGATGCACGATGCGCTGAACAGCAATATCTATGGCG AACCGGGTTGGATGGGTACCGCCTGGCGTGCAGGTCGTGACCTGAAACGCCGTGATATCGGTGGCAAAACCGGTACCACC AACAGTTCAAAAGACGCCTGGTTCTCCGGCTATGGCCCGGATACCGTGACGTCGGTATGGATTGGCTTCGATGACCACCG CCGTGACCTTGGCCGTGCAACGGTATCCGGTGCGATCCCGGATCAGGTTTCCGGCGGTGAAGGCGGTGCCAAGAGTGCGC AACCGGCATGGGATGACTTTATGAAAACCGCACTGGAAGGCATTCCAGAGCAGAAGGTGACCCCACCACCGGGCATTATC AGCGTTACCATCGACAAGAGCAGCGGTAAGCTTTCCGGCGGTGGCGGCGGCAGCCGTTCCGAGTACTTTATCGAAGGAAC TCAGCCGACGGACTATCCTTCACGAGATACCGGCACTACGCTGACGGATCCCGGCGGCGAAAGCCACGAGTTGTTCTAA
Upstream 100 bases:
>100_bases TCAGATAACAAAAGAACATATCCATGTTGCAGGCTTGCCTTTATACTACCGCGCGGTTGTTTATAAACTGCCCAAATGAC ATGAAAATGGGAAATCTCAG
Downstream 100 bases:
>100_bases CAAAAAAAGGGCCCAGATTCATCTGGGCCCTTTTTCATTTAACCGTCGCGCTTAGCGGGAGCCGCGTAAAAATGCCTCGG TGAGGAACAACGCACTCACG
Product: peptidoglycan synthetase
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 852; Mature: 852
Protein sequence:
>852_residues MKFVKYLLILAVCCIVLGAASIFGLYKYVEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPLKLNQIPPVMVH AFIATEDSRFYEHHGVDPIGIFRAASIALVSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKDVSQLSLSEMATIAGLPKAPSTFNPLYSHDRAVARRNVVLSRMLDEHYITQAQF DQARSEELVANYHAPEISFSAPYLSEMVRQEMIKRYGDNAYTDGYKVYTTVTKKLQLAAQDSVRNNVLAYDMRHGYRGPS NVLWKVGEAAWDQKQIVDSLKNLPNYGPLSPAVIVSTSAEEATAMMADGSHVALPMSTMRWARPYRSDTQQGPTPKRVTD VVQAGQQVWVRKVGENWWLSQVPDVNSALVSINPNDGAVKALVGGFDFNQSKFNRVTQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDAGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES LALGSASFTPMQLVRGYAVLANGGYLVDPYFITKIEDDNGNTVFETKPKIVCDSCNLPVIYGDTHRSAVLSEDNIENVAT SQEGKNGNVPMPQLEQVTPAQVQQDGDQQYAPHVISTPLAFLMHDALNSNIYGEPGWMGTAWRAGRDLKRRDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRDLGRATVSGAIPDQVSGGEGGAKSAQPAWDDFMKTALEGIPEQKVTPPPGII SVTIDKSSGKLSGGGGGSRSEYFIEGTQPTDYPSRDTGTTLTDPGGESHELF
Sequences:
>Translated_852_residues MKFVKYLLILAVCCIVLGAASIFGLYKYVEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPLKLNQIPPVMVH AFIATEDSRFYEHHGVDPIGIFRAASIALVSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKDVSQLSLSEMATIAGLPKAPSTFNPLYSHDRAVARRNVVLSRMLDEHYITQAQF DQARSEELVANYHAPEISFSAPYLSEMVRQEMIKRYGDNAYTDGYKVYTTVTKKLQLAAQDSVRNNVLAYDMRHGYRGPS NVLWKVGEAAWDQKQIVDSLKNLPNYGPLSPAVIVSTSAEEATAMMADGSHVALPMSTMRWARPYRSDTQQGPTPKRVTD VVQAGQQVWVRKVGENWWLSQVPDVNSALVSINPNDGAVKALVGGFDFNQSKFNRVTQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDAGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES LALGSASFTPMQLVRGYAVLANGGYLVDPYFITKIEDDNGNTVFETKPKIVCDSCNLPVIYGDTHRSAVLSEDNIENVAT SQEGKNGNVPMPQLEQVTPAQVQQDGDQQYAPHVISTPLAFLMHDALNSNIYGEPGWMGTAWRAGRDLKRRDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRDLGRATVSGAIPDQVSGGEGGAKSAQPAWDDFMKTALEGIPEQKVTPPPGII SVTIDKSSGKLSGGGGGSRSEYFIEGTQPTDYPSRDTGTTLTDPGGESHELF >Mature_852_residues MKFVKYLLILAVCCIVLGAASIFGLYKYVEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPLKLNQIPPVMVH AFIATEDSRFYEHHGVDPIGIFRAASIALVSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKDVSQLSLSEMATIAGLPKAPSTFNPLYSHDRAVARRNVVLSRMLDEHYITQAQF DQARSEELVANYHAPEISFSAPYLSEMVRQEMIKRYGDNAYTDGYKVYTTVTKKLQLAAQDSVRNNVLAYDMRHGYRGPS NVLWKVGEAAWDQKQIVDSLKNLPNYGPLSPAVIVSTSAEEATAMMADGSHVALPMSTMRWARPYRSDTQQGPTPKRVTD VVQAGQQVWVRKVGENWWLSQVPDVNSALVSINPNDGAVKALVGGFDFNQSKFNRVTQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDAGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES LALGSASFTPMQLVRGYAVLANGGYLVDPYFITKIEDDNGNTVFETKPKIVCDSCNLPVIYGDTHRSAVLSEDNIENVAT SQEGKNGNVPMPQLEQVTPAQVQQDGDQQYAPHVISTPLAFLMHDALNSNIYGEPGWMGTAWRAGRDLKRRDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRDLGRATVSGAIPDQVSGGEGGAKSAQPAWDDFMKTALEGIPEQKVTPPPGII SVTIDKSSGKLSGGGGGSRSEYFIEGTQPTDYPSRDTGTTLTDPGGESHELF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=852, Percent_Identity=78.5211267605634, Blast_Score=1428, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=251, Percent_Identity=35.8565737051793, Blast_Score=140, Evalue=3e-34, Organism=Escherichia coli, GI1788867, Length=261, Percent_Identity=34.4827586206897, Blast_Score=129, Evalue=1e-30, Organism=Escherichia coli, GI1789601, Length=176, Percent_Identity=37.5, Blast_Score=96, Evalue=1e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 93629; Mature: 93629
Theoretical pI: Translated: 6.93; Mature: 6.93
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFVKYLLILAVCCIVLGAASIFGLYKYVEPQLPDVATLKDVRLQIPMQVYSADGELIAQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCEEECCCCHHHHH YGEKRRIPLKLNQIPPVMVHAFIATEDSRFYEHHGVDPIGIFRAASIALVSGHASQGAST CCCCCCCCEEECCCCHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHEEEEECCCCCCHHH ITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEILELYLNKIYLGYRAYGVGAAA HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEE QVYFGKDVSQLSLSEMATIAGLPKAPSTFNPLYSHDRAVARRNVVLSRMLDEHYITQAQF EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DQARSEELVANYHAPEISFSAPYLSEMVRQEMIKRYGDNAYTDGYKVYTTVTKKLQLAAQ HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHH DSVRNNVLAYDMRHGYRGPSNVLWKVGEAAWDQKQIVDSLKNLPNYGPLSPAVIVSTSAE HHHHCCEEEEEHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCHH EATAMMADGSHVALPMSTMRWARPYRSDTQQGPTPKRVTDVVQAGQQVWVRKVGENWWLS HHHHEEECCCEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC QVPDVNSALVSINPNDGAVKALVGGFDFNQSKFNRVTQALRQVGSNIKPFLYTAAMDKGL CCCCCCCEEEEECCCCCCEEHEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC TLATILNDLPITRWDAGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDY CHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHCHHH AAEYLQRFGFPAQNIVHTESLALGSASFTPMQLVRGYAVLANGGYLVDPYFITKIEDDNG HHHHHHHCCCCHHHHEEHHHHCCCCCCCCHHHHHCCEEEEECCCEEECCEEEEEEECCCC NTVFETKPKIVCDSCNLPVIYGDTHRSAVLSEDNIENVATSQEGKNGNVPMPQLEQVTPA CEEEEECCCEEECCCCCCEEECCCCCCCEECCCCHHHHHCCCCCCCCCCCCCHHHCCCHH QVQQDGDQQYAPHVISTPLAFLMHDALNSNIYGEPGWMGTAWRAGRDLKRRDIGGKTGTT HHHCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCC NSSKDAWFSGYGPDTVTSVWIGFDDHRRDLGRATVSGAIPDQVSGGEGGAKSAQPAWDDF CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH MKTALEGIPEQKVTPPPGIISVTIDKSSGKLSGGGGGSRSEYFIEGTQPTDYPSRDTGTT HHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC LTDPGGESHELF CCCCCCCCCCCC >Mature Secondary Structure MKFVKYLLILAVCCIVLGAASIFGLYKYVEPQLPDVATLKDVRLQIPMQVYSADGELIAQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCEEECCCCHHHHH YGEKRRIPLKLNQIPPVMVHAFIATEDSRFYEHHGVDPIGIFRAASIALVSGHASQGAST CCCCCCCCEEECCCCHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHEEEEECCCCCCHHH ITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEILELYLNKIYLGYRAYGVGAAA HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEE QVYFGKDVSQLSLSEMATIAGLPKAPSTFNPLYSHDRAVARRNVVLSRMLDEHYITQAQF EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DQARSEELVANYHAPEISFSAPYLSEMVRQEMIKRYGDNAYTDGYKVYTTVTKKLQLAAQ HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHH DSVRNNVLAYDMRHGYRGPSNVLWKVGEAAWDQKQIVDSLKNLPNYGPLSPAVIVSTSAE HHHHCCEEEEEHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCHH EATAMMADGSHVALPMSTMRWARPYRSDTQQGPTPKRVTDVVQAGQQVWVRKVGENWWLS HHHHEEECCCEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC QVPDVNSALVSINPNDGAVKALVGGFDFNQSKFNRVTQALRQVGSNIKPFLYTAAMDKGL CCCCCCCEEEEECCCCCCEEHEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC TLATILNDLPITRWDAGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDY CHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHCHHH AAEYLQRFGFPAQNIVHTESLALGSASFTPMQLVRGYAVLANGGYLVDPYFITKIEDDNG HHHHHHHCCCCHHHHEEHHHHCCCCCCCCHHHHHCCEEEEECCCEEECCEEEEEEECCCC NTVFETKPKIVCDSCNLPVIYGDTHRSAVLSEDNIENVATSQEGKNGNVPMPQLEQVTPA CEEEEECCCEEECCCCCCEEECCCCCCCEECCCCHHHHHCCCCCCCCCCCCCHHHCCCHH QVQQDGDQQYAPHVISTPLAFLMHDALNSNIYGEPGWMGTAWRAGRDLKRRDIGGKTGTT HHHCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCC NSSKDAWFSGYGPDTVTSVWIGFDDHRRDLGRATVSGAIPDQVSGGEGGAKSAQPAWDDF CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH MKTALEGIPEQKVTPPPGIISVTIDKSSGKLSGGGGGSRSEYFIEGTQPTDYPSRDTGTT HHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC LTDPGGESHELF CCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3882429; 9278503; 3920658; 7006606; 9841666 [H]