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The map label for this gene is pyrH [H]

Identifier: 145295927

GI number: 145295927

Start: 2056944

End: 2057708

Strand: Reverse

Name: pyrH [H]

Synonym: cgR_1852

Alternate gene names: 145295927

Gene position: 2057708-2056944 (Counterclockwise)

Preceding gene: 145295928

Following gene: 145295926

Centisome position: 62.09

GC content: 53.46

Gene sequence:

>765_bases
TTGGCACAACCCCTACTGAAGGAGAACACCACGGTGACCACCTCAAGTGAACAACCCCGTACAGGATACAAACGAGTGAT
GTTAAAGCTCGGAGGTGAAATGTTTGGTGGTGGCAAAGTCGGCGTCGATCCTGATGTAGTTGACAATGTTGCACGTCAGA
TCGCTGAAGTTGCTAAAACTGGAGCAGAGATTGCCGTTGTTATCGGTGGCGGAAACTTCTTCCGCGGAGCTGAGCTTCAG
CAGCGTGGCATGGATCGCGCACGGTCCGATTACATGGGCATGCTCGGCACAGTCATGAACTGCCTCGCCTTGCAGGACTT
CCTCGGTCAGCATGGCGTTGAATGCCGTGTCCAGACAGCCATCAACATGGCACAGGTTGCAGAACCATATCTGCCACTGC
GTGCAGAACGCCACCTGGAAAAGGGCCGCGTTGTCATCTTCGGTGCTGGCATGGGTATGCCGTACTTTTCCACAGACACC
ACTGCTGCACAGCGTGCGTTGGAAATCGGCTGTGACGTCCTGCTGATGGCTAAGGCTGTTGACGGTGTGTACAGCGATGA
TCCTCGTACCAACCCAGATGCTGAGCTCTTCACCGAAATTACTCCAAAGGAAGTAATTGAGAAGGGCCTGAAGGTTGCCG
ATGCAACTGCATTCAGCCTCTGCATGGACAACAAGATGCCTATCTTGGTGTTTAACCTGCTTACTGAAGGCAACATTGCT
CGCGCCATCAGCGGTGAACGTATCGGTACTCTGGTCGAGTCCTGA

Upstream 100 bases:

>100_bases
TCGAATCCCAGGAATAGGGGTGCCCTGAATTTGGGTCTCAGTGGCTTCTTGGTTGCTGTGATTTTTTCAAGGCGTACCCC
GTGGCCGATGTTAAAAGCGG

Downstream 100 bases:

>100_bases
TACATTTAGTCTTATAAACAGCGTGGCTTATCTAGGTTCGATTCTAGGATCCATCAGAATCCACGCTGTTAGAAAAACAC
AGGAGTGAATAAATGATTGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MAQPLLKENTTVTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQ
QRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDT
TAAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIA
RAISGERIGTLVES

Sequences:

>Translated_254_residues
MAQPLLKENTTVTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQ
QRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDT
TAAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIA
RAISGERIGTLVES
>Mature_253_residues
AQPLLKENTTVTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQQ
RGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTT
AAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIAR
AISGERIGTLVES

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=45.4545454545455, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27379; Mature: 27248

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPLLKENTTVTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKT
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTA
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
INMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAV
HHHHHHHCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
DGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIA
CCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCH
RAISGERIGTLVES
HHHCCCHHHHHHCC
>Mature Secondary Structure 
AQPLLKENTTVTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKT
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTA
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
INMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAV
HHHHHHHCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
DGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIA
CCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCH
RAISGERIGTLVES
HHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]