Click here to switch to the map view.

The map label for this gene is frr

Identifier: 145295926

GI number: 145295926

Start: 2056294

End: 2056851

Strand: Reverse

Name: frr

Synonym: cgR_1851

Alternate gene names: 145295926

Gene position: 2056851-2056294 (Counterclockwise)

Preceding gene: 145295927

Following gene: 145295925

Centisome position: 62.06

GC content: 51.61

Gene sequence:

>558_bases
ATGATTGATGAAATTCTGTTCGAAGCGGAAGAGCGCATGACCGCAACGGTCGAGCACACCCGCGAAGACTTGACCACCAT
TCGTACCGGTCGCGCAAACCCGGCTATGTTCAACGGTGTCATGGCTGAATACTACGGCGTGCCTACTCCTATTACTCAGA
TGTCAAGCATCTCTGTTCCAGAGCCTCGCATGCTGCTGATCAAGCCTTATGAGATGTCTTCTATGCAGGTCATTGAGAAT
GCTATCCGTAACTCTGACCTTGGTGTTAACCCCACCAACGATGGCCAGGTGCTGCGTGTGACCATCCCACAGCTCACTGA
AGAGCGTCGTAAGGACATGGTCAAGCTTGCTAAGGGTAAGGGCGAAGACGGCAAGATTGCCATTCGTAACATCCGCCGCA
AGGGCATGGACCAGCTAAAGAAGCTGCAAAAAGATGGCGACGCTGGCGAAGATGAAGTACAGGCAGCAGAAAAAGAACTA
GATAAAGTCACCGCTGGTTTTGTTGCGCAGGTCGATGAAGTCGTTGCTCGCAAGGAAAAGGAACTGATGGAGGTCTAG

Upstream 100 bases:

>100_bases
AGTCCTGATACATTTAGTCTTATAAACAGCGTGGCTTATCTAGGTTCGATTCTAGGATCCATCAGAATCCACGCTGTTAG
AAAAACACAGGAGTGAATAA

Downstream 100 bases:

>100_bases
AAGACCTTTATCGCAATGGCTTAAGAATTACGTCGTTTCAACGTCGATTGGGCGGGGAAACGACGCTTTCTTTTGCTTGC
AAGAGTGTTTGGAAGAATTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV

Sequences:

>Translated_185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV
>Mature_185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=30.5555555555556, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI291042689, Length=135, Percent_Identity=35.5555555555556, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=40.7608695652174, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=24.2774566473988, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CORGB (A4QF29)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138747.1
- ProteinModelPortal:   A4QF29
- SMR:   A4QF29
- STRING:   A4QF29
- GeneID:   4991583
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1851
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20765; Mature: 20765

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPRMLLIKPYEMSSMQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGK
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKELDKVTAGFVAQVDEVVARKEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPRMLLIKPYEMSSMQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGK
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKELDKVTAGFVAQVDEVVARKEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA