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The map label for this gene is 121639442

Identifier: 121639442

GI number: 121639442

Start: 3938421

End: 3939605

Strand: Direct

Name: 121639442

Synonym: BCG_3587

Alternate gene names: NA

Gene position: 3938421-3939605 (Clockwise)

Preceding gene: 121639441

Following gene: 121639443

Centisome position: 90.03

GC content: 65.49

Gene sequence:

>1185_bases
ATGGCCGGAAAGCTGGCCGCCGTACTCGGCACCGGGCAGACCAAGTATGTCGCCAAGCGCCAAGACGTTTCGATGAACGG
TCTGGTGCGGGAGGCCATCGACCGAGCGCTGGCGGATTCCGGTTCCACCTTCGACGACATCGACGCCGTCGTGGTCGGCA
AGGCGCCCGACTTCTTCGAAGGGGTGATGATGCCGGAGCTATTCATGGCCGACGCCATGGGCGCGACCGGCAAGCCGCTG
ATCCGGGTACACACCGCCGGTTCGGTTGGCGGATCCACCGGGGTAGTGGCTGCCAGCCTGGTGCAATCCGGCAAATACCG
CCGGGTCCTGGCATTAGCCTGGGAAAAGCAGTCGGAATCCAATGCCATGTGGGCGTTGTCGATTCCTGTGCCGTTCACCA
AACCGGTCGGTGCCGGTGCGGGGGGATACTTCGCCCCGCATGTCCGGGCCTATATCCGCCGCTCGGGCGCACCGGCACAC
ATCGGTGCTATGGTTGCGGTCAAGGACCGGCTCAACGGCAGCCGCAACCCGTTGGCACATCTGCAGCAGCCCGACATCAC
CCTGGAGAAGGTGATGGCATCTCAGATGCTCTGGGATCCAATACGTTTCGATGAGACGTGCCCGTCGTCAGACGGTGCGT
GCGCGGTTGTCGTCGGCGACGAGGAGATCGCCGACGCGCGACTGGCGCAAGGGCATCCGGTGGCCTGGATTCATGGCACC
GCATTACGCACCGAGCCGCTGGCTTTCGCCGGGCGCGACCAGGTCAACCCGCAGGCCGGCCGCGACGCGGCGGCGGCGCT
GTGGAAGGCCGCGGGCATCACCAGCCCCATCGACGAAATCGACGCCGCCGAAATTTACGTCCCGTTCTCCTGGTTCGAGC
CGATGTGGTTGGAGAATCTGGGATTTGCCCGCGAGGGCGAGGGCTGGAAGCTCACCGAGGCCGGCGAGACTGCGATCGGC
GGTCGACTACCGGTGAACCCTTCCGGCGGCGTGCTGTCCGCCAATCCGATCGGCGCATCGGGCCTGATCCGCTTCGCCGA
GGCCGCGATCCAAGTCATGGGCAAGGCGGAGGCGCGTCAAGTTCCGGGTGCGCGAAAGGCCTTGGGGCACGCTTACGGTG
GCGGCTCGCAGTACTTCTCTATGTGGGTGGTCGGCTGCGAGAAACCCAAACAGGCAGCCGCATAA

Upstream 100 bases:

>100_bases
TCGGCGCGGCGCGTGCTGGCGCACGCCACCAGCGGACCGGCGCTGCAGCAAAACCTGGTCGCGGTCATGGAAGGACGGGG
ATAGTGGAGGGGCAGCGCTG

Downstream 100 bases:

>100_bases
TCGCCCGGCGCGATCCGGGCGACGCCGCAGACCATCCGAGCATGGTGAAGTTCACACCCGATAGCCAGACGTCAGTTCTG
CGCGCGGGCAAGTGCTCAGG

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MAGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFEGVMMPELFMADAMGATGKPL
IRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAH
IGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGT
ALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENLGFAREGEGWKLTEAGETAIG
GRLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA

Sequences:

>Translated_394_residues
MAGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFEGVMMPELFMADAMGATGKPL
IRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAH
IGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGT
ALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENLGFAREGEGWKLTEAGETAIG
GRLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
>Mature_393_residues
AGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLI
RVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHI
GAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTA
LRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENLGFAREGEGWKLTEAGETAIGG
RLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=397, Percent_Identity=29.7229219143577, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI302344760, Length=331, Percent_Identity=30.2114803625378, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI302344767, Length=327, Percent_Identity=30.2752293577982, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI302344762, Length=294, Percent_Identity=30.2721088435374, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI55956775, Length=249, Percent_Identity=28.1124497991968, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=388, Percent_Identity=25.5154639175258, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI19921506, Length=400, Percent_Identity=29.5, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24585051, Length=407, Percent_Identity=29.2383292383292, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 41422; Mature: 41290

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFE
CCCCEEEEEECCCCCEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHH
GVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSES
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCC
NAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAH
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEEEHHHCCCCCCCHHH
LQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEECC
ALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENL
EECCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEEHHHCCCHHHHHC
GFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQ
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
VPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
CCCHHHHHHHCCCCCCCEEEEEEEECCCCHHCCC
>Mature Secondary Structure 
AGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFE
CCCEEEEEECCCCCEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHH
GVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSES
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCC
NAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAH
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEEEHHHCCCCCCCHHH
LQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEECC
ALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENL
EECCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEEHHHCCCHHHHHC
GFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQ
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
VPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
CCCHHHHHHHCCCCCCCEEEEEEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]