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The map label for this gene is pgtB [H]

Identifier: 119776374

GI number: 119776374

Start: 3836310

End: 3838673

Strand: Direct

Name: pgtB [H]

Synonym: Sama_3242

Alternate gene names: 119776374

Gene position: 3836310-3838673 (Clockwise)

Preceding gene: 119776373

Following gene: 119776375

Centisome position: 89.09

GC content: 55.84

Gene sequence:

>2364_bases
ATGTCCAAGTCTCACTCACCCCTTGGCAGAAGGCTCTTTATTGCCTTTTCGGCCATGTTGGGGCTGACACTGTTGGTCGG
CCTGACCAGCCTGCTGATGTGGGACCGACTGAGTGCCCGGGTCAGCAGCATCATCAGTGAAAGCGTGCCCACCATCAATG
CTACCTACACACTGGAACGTGCCAGCAACAGGCTGTTGCAGCTTTTGGGACAACTGCCCGGCGCCGAGGATGAAATCACC
CTGCTGACCATGGAGCGGCAGGTATCCGAAGCCATGGGTGAACTCGAAAATGCCTATCTGGTCAACCTGCACAGCGACGA
TGAGCGGGCACTGCAACAGGCCCGCTTCGGTGAGCTTGAAGCATTAATCCACAACCAGAGTCAGCTCCTGCGACACCAAC
TCACCCTGGCGCAGCATCTTTCGTCGCAGCAAAAGCAGCTGGCGCGACTGCATCAGGATTTAACGGATGAAATGACGCCG
CTGCTGCAGGAAGTGGCCTGGCACTTAAGCGCCCAGCTTGGCAACCGCACCTCGGCCACTACCATCACTTCTGTGCTGCA
GGAATTTTCGGTGCTGCAAAATATCGCCTTGAAAGAAAACGAGATTCATCAGCTCAGCACCGAGATTATCAACCAGCGCC
ATCAAAGGGAGCTGGAGCATGCCTTCTCGTTTATTGGTTTTCAAATCGACGAGTTGAAGCTGCTCACCACTCAGCTTGCC
GCCTACCCATCGACTGTGAGCCATCGCCAGATATTGCAGGAACTGGTGGATCTGGTGAAACCCGGTGGAGCCCTGCATCA
ACTGCTCGGCGAAGACGTGGGAAACCAACTTAAAATCAAATCATTGCAACCAAAGATCAATGAGCTTATTCAGCCCTATC
ATGCCCAGGTGGTGACCGCCGTCGCTCAAGCCAACACCAACCTGGAGTCATTGGTGCAAGCCACCAACCGCCAGGTAAGC
CAGGGCAAAGCCTGGCTGCTGCTTATCCTCACAGGGGCACTGATCTTAAGCACCTTTGTGCTGACCGGCCTGATTTCACG
GCGCCTGATTGGCCGCCTGAATCTGCTTAGCGAGGATTTGGCAAAGGTGTGCAGCAACGACCTGTCGAGCCCTCTTAGCG
TGCGTGGTAGAGATGAAATTGGCCGCCTCGGCGAGCAGTTGCTGCAGTTTCGCGCCCAGCGGCAACTGATGGACAAAACC
AATGCACTCAACCTGATTAACAACACCCAGGCCTGCCTTATCACCTGTCTGATGGACGGCACCATAGAATCGGTCAACCC
CACTGCGAGAAAGTTGTTACCCCTTGGAACTGAACCTGAGCAATCGCTGCTGTGGCAGGCCTTTCCCCCTGCGGCGGCTC
AGCAGCTGGCAGACCAGTTTGCCCCCGGCAGTACCTTACAAGGGCTCGGTCAAAGCCATTGTCTGCTGGAGCTGGGCGAC
GATGATCGGCGGGCCTTCTGGCACTTCGATTTTCGCCGCTATGAGCAAGCGGGGGAGTTTAAGACCATTATCACCATCAC
AGACATGACCCGTCAGGAGCTGAATGCCCGCGAGCTGTCGGAGCGGGTTGCCGAACGAACCCGGGATCTTAAGGAAAAAA
ATCAGCAGCTTGAGCAAGAAGTAGAGCGTCGCACCCAGGCGCAGAACGACCTGTTGCGCGCCCAGGATGAACTCATTCAG
GCCGCCAAGATGGCGGTGCTGGGCCAGGCCATGACCAGTATGGCCCATGAGTTGAACCAGCCACTGTCGGCTATTTCCAC
CTTCCTCTACACCAGCCGTATGGCCGCCGAACAAGGCGATACAGCCCTGCTTACCGACAATCTGGAACGTATAGGTCAGC
TGAGTAAACGGATGCACCGCATCGTGGGCGCCTTGAAAGAATTTGCCCGCAAGAGCCCGCAAACCCGGGTCAGGGAAGCC
GTTTCACTGGGCACCATAGCCGATAATGCCCTGCTGCTGCTCGCCCCCCGGATAAAACGCGAGAATGTGCAGGTAGAAAG
CCACCTCGACAGCAGCCTCTGTGTTATCGGCGACCCGGTTGAGATAGAACAGGTGCTGATCAATCTGTTGGTCAATGCGC
TCGATGCCATTGCAAGCTGCGAGCAAAAGCACATCCTTATAGAACAGTTCCCACAACCCGGCAGCACCCTTTTAGCCATT
CGCGACAACGGCCACGGTTTTCCCGATGCTGTGTTGCAAAAGCTGTTTTCGCCTTTTGTTACCACCAAAGAAGTGGGGCT
GGGCCTCGGACTTTCGATTTGCCGAACCCTGATGGAACGCCAGGAAGGCGATATCCGCCTTGCCTGCGCTATGGACGGCA
ACACCCTGATGCTGTTGGAGTTTACAAATGTCCCATCTGCTTAA

Upstream 100 bases:

>100_bases
CCTCGGCGCAGATGGAGCGCACCATGCAGGATTGGCGCATGCAGGTGGCACAGCAGCTTGAGCAGGCCATGGCACTGGTT
CGCACCCTGGAGTACCCCTG

Downstream 100 bases:

>100_bases
ACCCAAGCCTAATCTGCTGCTTATAGACGATGATGAAGACGTACTGGACGCTTGCCGCCAGTTGTTTAACTTATCCGGCT
ATCAGGTGCGGGCAACCAAC

Product: phosphoglycerate transport regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MSKSHSPLGRRLFIAFSAMLGLTLLVGLTSLLMWDRLSARVSSIISESVPTINATYTLERASNRLLQLLGQLPGAEDEIT
LLTMERQVSEAMGELENAYLVNLHSDDERALQQARFGELEALIHNQSQLLRHQLTLAQHLSSQQKQLARLHQDLTDEMTP
LLQEVAWHLSAQLGNRTSATTITSVLQEFSVLQNIALKENEIHQLSTEIINQRHQRELEHAFSFIGFQIDELKLLTTQLA
AYPSTVSHRQILQELVDLVKPGGALHQLLGEDVGNQLKIKSLQPKINELIQPYHAQVVTAVAQANTNLESLVQATNRQVS
QGKAWLLLILTGALILSTFVLTGLISRRLIGRLNLLSEDLAKVCSNDLSSPLSVRGRDEIGRLGEQLLQFRAQRQLMDKT
NALNLINNTQACLITCLMDGTIESVNPTARKLLPLGTEPEQSLLWQAFPPAAAQQLADQFAPGSTLQGLGQSHCLLELGD
DDRRAFWHFDFRRYEQAGEFKTIITITDMTRQELNARELSERVAERTRDLKEKNQQLEQEVERRTQAQNDLLRAQDELIQ
AAKMAVLGQAMTSMAHELNQPLSAISTFLYTSRMAAEQGDTALLTDNLERIGQLSKRMHRIVGALKEFARKSPQTRVREA
VSLGTIADNALLLLAPRIKRENVQVESHLDSSLCVIGDPVEIEQVLINLLVNALDAIASCEQKHILIEQFPQPGSTLLAI
RDNGHGFPDAVLQKLFSPFVTTKEVGLGLGLSICRTLMERQEGDIRLACAMDGNTLMLLEFTNVPSA

Sequences:

>Translated_787_residues
MSKSHSPLGRRLFIAFSAMLGLTLLVGLTSLLMWDRLSARVSSIISESVPTINATYTLERASNRLLQLLGQLPGAEDEIT
LLTMERQVSEAMGELENAYLVNLHSDDERALQQARFGELEALIHNQSQLLRHQLTLAQHLSSQQKQLARLHQDLTDEMTP
LLQEVAWHLSAQLGNRTSATTITSVLQEFSVLQNIALKENEIHQLSTEIINQRHQRELEHAFSFIGFQIDELKLLTTQLA
AYPSTVSHRQILQELVDLVKPGGALHQLLGEDVGNQLKIKSLQPKINELIQPYHAQVVTAVAQANTNLESLVQATNRQVS
QGKAWLLLILTGALILSTFVLTGLISRRLIGRLNLLSEDLAKVCSNDLSSPLSVRGRDEIGRLGEQLLQFRAQRQLMDKT
NALNLINNTQACLITCLMDGTIESVNPTARKLLPLGTEPEQSLLWQAFPPAAAQQLADQFAPGSTLQGLGQSHCLLELGD
DDRRAFWHFDFRRYEQAGEFKTIITITDMTRQELNARELSERVAERTRDLKEKNQQLEQEVERRTQAQNDLLRAQDELIQ
AAKMAVLGQAMTSMAHELNQPLSAISTFLYTSRMAAEQGDTALLTDNLERIGQLSKRMHRIVGALKEFARKSPQTRVREA
VSLGTIADNALLLLAPRIKRENVQVESHLDSSLCVIGDPVEIEQVLINLLVNALDAIASCEQKHILIEQFPQPGSTLLAI
RDNGHGFPDAVLQKLFSPFVTTKEVGLGLGLSICRTLMERQEGDIRLACAMDGNTLMLLEFTNVPSA
>Mature_786_residues
SKSHSPLGRRLFIAFSAMLGLTLLVGLTSLLMWDRLSARVSSIISESVPTINATYTLERASNRLLQLLGQLPGAEDEITL
LTMERQVSEAMGELENAYLVNLHSDDERALQQARFGELEALIHNQSQLLRHQLTLAQHLSSQQKQLARLHQDLTDEMTPL
LQEVAWHLSAQLGNRTSATTITSVLQEFSVLQNIALKENEIHQLSTEIINQRHQRELEHAFSFIGFQIDELKLLTTQLAA
YPSTVSHRQILQELVDLVKPGGALHQLLGEDVGNQLKIKSLQPKINELIQPYHAQVVTAVAQANTNLESLVQATNRQVSQ
GKAWLLLILTGALILSTFVLTGLISRRLIGRLNLLSEDLAKVCSNDLSSPLSVRGRDEIGRLGEQLLQFRAQRQLMDKTN
ALNLINNTQACLITCLMDGTIESVNPTARKLLPLGTEPEQSLLWQAFPPAAAQQLADQFAPGSTLQGLGQSHCLLELGDD
DRRAFWHFDFRRYEQAGEFKTIITITDMTRQELNARELSERVAERTRDLKEKNQQLEQEVERRTQAQNDLLRAQDELIQA
AKMAVLGQAMTSMAHELNQPLSAISTFLYTSRMAAEQGDTALLTDNLERIGQLSKRMHRIVGALKEFARKSPQTRVREAV
SLGTIADNALLLLAPRIKRENVQVESHLDSSLCVIGDPVEIEQVLINLLVNALDAIASCEQKHILIEQFPQPGSTLLAIR
DNGHGFPDAVLQKLFSPFVTTKEVGLGLGLSICRTLMERQEGDIRLACAMDGNTLMLLEFTNVPSA

Specific function: Member of the two-component regulatory system pgtB/pgtA that regulates the inducible phosphoglycerate transport system. Activates pgtA by phosphorylation [H]

COG id: COG4192

COG function: function code T; Signal transduction histidine kinase regulating phosphoglycerate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=31.0185185185185, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.6324786324786, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=289, Percent_Identity=25.6055363321799, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=25.9541984732824, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017116 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87608; Mature: 87477

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSHSPLGRRLFIAFSAMLGLTLLVGLTSLLMWDRLSARVSSIISESVPTINATYTLER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
ASNRLLQLLGQLPGAEDEITLLTMERQVSEAMGELENAYLVNLHSDDERALQQARFGELE
HHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
ALIHNQSQLLRHQLTLAQHLSSQQKQLARLHQDLTDEMTPLLQEVAWHLSAQLGNRTSAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TITSVLQEFSVLQNIALKENEIHQLSTEIINQRHQRELEHAFSFIGFQIDELKLLTTQLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AYPSTVSHRQILQELVDLVKPGGALHQLLGEDVGNQLKIKSLQPKINELIQPYHAQVVTA
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEHHCCHHHHHHHHHHHHHHHHH
VAQANTNLESLVQATNRQVSQGKAWLLLILTGALILSTFVLTGLISRRLIGRLNLLSEDL
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVCSNDLSSPLSVRGRDEIGRLGEQLLQFRAQRQLMDKTNALNLINNTQACLITCLMDG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
TIESVNPTARKLLPLGTEPEQSLLWQAFPPAAAQQLADQFAPGSTLQGLGQSHCLLELGD
CCCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCCEEEEECC
DDRRAFWHFDFRRYEQAGEFKTIITITDMTRQELNARELSERVAERTRDLKEKNQQLEQE
CCCCEEEHHHHHHHHHCCCEEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VERRTQAQNDLLRAQDELIQAAKMAVLGQAMTSMAHELNQPLSAISTFLYTSRMAAEQGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
TALLTDNLERIGQLSKRMHRIVGALKEFARKSPQTRVREAVSLGTIADNALLLLAPRIKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCHHH
ENVQVESHLDSSLCVIGDPVEIEQVLINLLVNALDAIASCEQKHILIEQFPQPGSTLLAI
CCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEE
RDNGHGFPDAVLQKLFSPFVTTKEVGLGLGLSICRTLMERQEGDIRLACAMDGNTLMLLE
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEEEE
FTNVPSA
ECCCCCC
>Mature Secondary Structure 
SKSHSPLGRRLFIAFSAMLGLTLLVGLTSLLMWDRLSARVSSIISESVPTINATYTLER
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
ASNRLLQLLGQLPGAEDEITLLTMERQVSEAMGELENAYLVNLHSDDERALQQARFGELE
HHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
ALIHNQSQLLRHQLTLAQHLSSQQKQLARLHQDLTDEMTPLLQEVAWHLSAQLGNRTSAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TITSVLQEFSVLQNIALKENEIHQLSTEIINQRHQRELEHAFSFIGFQIDELKLLTTQLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AYPSTVSHRQILQELVDLVKPGGALHQLLGEDVGNQLKIKSLQPKINELIQPYHAQVVTA
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEHHCCHHHHHHHHHHHHHHHHH
VAQANTNLESLVQATNRQVSQGKAWLLLILTGALILSTFVLTGLISRRLIGRLNLLSEDL
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVCSNDLSSPLSVRGRDEIGRLGEQLLQFRAQRQLMDKTNALNLINNTQACLITCLMDG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
TIESVNPTARKLLPLGTEPEQSLLWQAFPPAAAQQLADQFAPGSTLQGLGQSHCLLELGD
CCCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCCEEEEECC
DDRRAFWHFDFRRYEQAGEFKTIITITDMTRQELNARELSERVAERTRDLKEKNQQLEQE
CCCCEEEHHHHHHHHHCCCEEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VERRTQAQNDLLRAQDELIQAAKMAVLGQAMTSMAHELNQPLSAISTFLYTSRMAAEQGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
TALLTDNLERIGQLSKRMHRIVGALKEFARKSPQTRVREAVSLGTIADNALLLLAPRIKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCHHH
ENVQVESHLDSSLCVIGDPVEIEQVLINLLVNALDAIASCEQKHILIEQFPQPGSTLLAI
CCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEE
RDNGHGFPDAVLQKLFSPFVTTKEVGLGLGLSICRTLMERQEGDIRLACAMDGNTLMLLE
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEEEE
FTNVPSA
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2842311; 11677609; 2842312 [H]