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The map label for this gene is blh [H]

Identifier: 116689767

GI number: 116689767

Start: 1941684

End: 1943354

Strand: Direct

Name: blh [H]

Synonym: Bcen2424_1746

Alternate gene names: 116689767

Gene position: 1941684-1943354 (Clockwise)

Preceding gene: 116689766

Following gene: 116689768

Centisome position: 55.73

GC content: 71.27

Gene sequence:

>1671_bases
ATGACCACCCTCCGCAAGCTGACCGACGCGCTGTCGGTCTCGCCGCAGATCGCGGCGGCCGACCTGCCCGCGCTTCACGC
GGCGGGCATCCGCGCGATCATCTGCAACCGGCCCGACGGCGAAGGCGCCGACCAGCCGACCGTCACCGAGATCCGCGCGG
CCGCCGCGCCGCTCGGCATCGGTGTGCATTACCTGCCGGTCGATACCGGCACGGTGACCGACGACCAGGCTGCGCAGTTC
GGCGCGCTCGTCGCGTCGCTCGACGGGCCCGTGCTCGCGTACTGCCGCAGCGGCACGCGTTCGGCCACGCTGTGGGCGCT
GTCGCAGGCGGGGCTGCGTCCGCTGGACGACCTCGTCGCCACCGCCGGCGCAGCCGGCTACGACCTGAGCGCGCTTGCAT
CGCGTGTCACGCAAAACAGCCGCCACACGGCGCCCGCCGTCGACGCACGGCACGACATCGTGATCGTCGGCGCCGGTGCG
GCCGGCATCGCCGTCGCGTCGAGCCTGCTCGCGCGCGACGCGTCGCTCGACATCGCGGTGATCGATCCCGCCGACGTCCA
CTATTACCAGCCCGGCTGGACGATGGTCGGCGCGGGCGTGTTCCAGGCCGGCACCACCGCGCGGCCGATGACCGACGTGC
TGCCGCGCGGTGTACACCGCATCCGGGCCGCCGTCACGGGCTTCGAGCCCGACGCGCACGTCGTGGTGCTCGACGGCTGC
CGACGCATCGGTTATCGCAAGCTCGTCGTGTGCCCGGGGCTCAAGCTCGACTGGCACGCGATCGACGGCCTCGCCGACAC
GCTCGGCCACAACGGCGTCACGTCGAACTACCGCTACGATCTCGCGCCGTACACGTGGGAACTTGTGCGCGCGTTCCGCG
GCGGCAATGCGCTCTTCACGCAGCCGCCGATGCCGATCAAGTGCGCGGGCGCGCCGCAAAAGGCGATGTACCTGTCGTGC
GATCACTGGCGGCGCACGGGGCGCCTCGGCGCCGCGAACGTCGAATTCCTGAATGCGGGCGGCGCGCTGTTCGGCGTCGC
CGATTACGTGCCTGCGCTGATGGAGTACGTGAAAAGCTACGACATCGCGCTGTCGTTCGGCCACAACCTCGTCGCGATCG
ACGGGCCCGCGCGCCGTGCGACGTTCTCGCGCGCGCTGCCCGACGGCGGCAAGGCAACCGTCGAGCGTTCGTTCGACATG
ATCCACGTCGTGCCGCCGCAGAAGGCGCCCGACTTCGTGCGCGCAAGCCCGCTCGTCGACGCGGCCGGCTGGATCGACGT
CGATCCGGCGACGCTGCGCCACAAGCAGTTCGAGGACATCTACGCGCTCGGCGACGTCACCAACACGACCAATGCGAAAA
CGGCCGCGGCCGCGCGCAAGCAGGCGCCCGTCGTCGCGCACAACCTGCTCGCGTCGCTCGGCCGCGCGCACGGCGACGCC
GCGTACGACGGCTACGGCTCGTGCCCGCTCACCGTCGAGCGCGGCAAGATCGTGCTCGCCGAATTCCTGTACGGCGGCAA
GGTCGCGCCGACCTTCCCCGCGTGGCTGATCGACGGCAAACGCCCGTCGCGGCTCGCGTGGCTGCTCAAGGAGCGCGTGC
TGCCGCCGCTCTACTGGAAGGCGATGCTCAAGGGCCGCGAATGGCTCGCGAAGCCCGCGATCGCGCGTTGA

Upstream 100 bases:

>100_bases
CGCGCCGGCCACCTGCCCGAACCCGAGAACAACGGCGTGCGCTACCTGAAGATTCCGCTCGACGCGATCTGAGCGCCCGA
ACCCCACCGAGAACTCCGAC

Downstream 100 bases:

>100_bases
CCGGAGCCGGATGACGTCATGCTGATTTCCCTCGTACTCGGCGGCTTCGTCGGCGCCGTGCTCGGTTTGACCGGCGCCGG
CGGCGGCATTCTTGCGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MTTLRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGADQPTVTEIRAAAAPLGIGVHYLPVDTGTVTDDQAAQF
GALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLDDLVATAGAAGYDLSALASRVTQNSRHTAPAVDARHDIVIVGAGA
AGIAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFQAGTTARPMTDVLPRGVHRIRAAVTGFEPDAHVVVLDGC
RRIGYRKLVVCPGLKLDWHAIDGLADTLGHNGVTSNYRYDLAPYTWELVRAFRGGNALFTQPPMPIKCAGAPQKAMYLSC
DHWRRTGRLGAANVEFLNAGGALFGVADYVPALMEYVKSYDIALSFGHNLVAIDGPARRATFSRALPDGGKATVERSFDM
IHVVPPQKAPDFVRASPLVDAAGWIDVDPATLRHKQFEDIYALGDVTNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDA
AYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR

Sequences:

>Translated_556_residues
MTTLRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGADQPTVTEIRAAAAPLGIGVHYLPVDTGTVTDDQAAQF
GALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLDDLVATAGAAGYDLSALASRVTQNSRHTAPAVDARHDIVIVGAGA
AGIAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFQAGTTARPMTDVLPRGVHRIRAAVTGFEPDAHVVVLDGC
RRIGYRKLVVCPGLKLDWHAIDGLADTLGHNGVTSNYRYDLAPYTWELVRAFRGGNALFTQPPMPIKCAGAPQKAMYLSC
DHWRRTGRLGAANVEFLNAGGALFGVADYVPALMEYVKSYDIALSFGHNLVAIDGPARRATFSRALPDGGKATVERSFDM
IHVVPPQKAPDFVRASPLVDAAGWIDVDPATLRHKQFEDIYALGDVTNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDA
AYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR
>Mature_555_residues
TTLRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGADQPTVTEIRAAAAPLGIGVHYLPVDTGTVTDDQAAQFG
ALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLDDLVATAGAAGYDLSALASRVTQNSRHTAPAVDARHDIVIVGAGAA
GIAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFQAGTTARPMTDVLPRGVHRIRAAVTGFEPDAHVVVLDGCR
RIGYRKLVVCPGLKLDWHAIDGLADTLGHNGVTSNYRYDLAPYTWELVRAFRGGNALFTQPPMPIKCAGAPQKAMYLSCD
HWRRTGRLGAANVEFLNAGGALFGVADYVPALMEYVKSYDIALSFGHNLVAIDGPARRATFSRALPDGGKATVERSFDMI
HVVPPQKAPDFVRASPLVDAAGWIDVDPATLRHKQFEDIYALGDVTNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAA
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=406, Percent_Identity=36.4532019704434, Blast_Score=305, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI115534373, Length=341, Percent_Identity=35.4838709677419, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17539680, Length=421, Percent_Identity=31.1163895486936, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24657386, Length=397, Percent_Identity=36.272040302267, Blast_Score=253, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24657391, Length=397, Percent_Identity=36.272040302267, Blast_Score=253, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 59092; Mature: 58961

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGADQPTVTEIRAAAAPLGI
CCHHHHHHHHHCCCCCHHHCCCCHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
GVHYLPVDTGTVTDDQAAQFGALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLDDLVA
CEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHCCCCHHHHHHH
TAGAAGYDLSALASRVTQNSRHTAPAVDARHDIVIVGAGAAGIAVASSLLARDASLDIAV
HCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEE
IDPADVHYYQPGWTMVGAGVFQAGTTARPMTDVLPRGVHRIRAAVTGFEPDAHVVVLDGC
ECCCCCEEECCCCEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
RRIGYRKLVVCPGLKLDWHAIDGLADTLGHNGVTSNYRYDLAPYTWELVRAFRGGNALFT
HHCCCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEE
QPPMPIKCAGAPQKAMYLSCDHWRRTGRLGAANVEFLNAGGALFGVADYVPALMEYVKSY
CCCCCEEECCCCCCEEEEECHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
DIALSFGHNLVAIDGPARRATFSRALPDGGKATVERSFDMIHVVPPQKAPDFVRASPLVD
CEEEECCCEEEEECCCHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCHHCCCCCC
AAGWIDVDPATLRHKQFEDIYALGDVTNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDA
CCCCEECCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCC
AYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWK
CCCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
AMLKGREWLAKPAIAR
HHHHCHHHHCCCCCCC
>Mature Secondary Structure 
TTLRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGADQPTVTEIRAAAAPLGI
CHHHHHHHHHCCCCCHHHCCCCHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
GVHYLPVDTGTVTDDQAAQFGALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLDDLVA
CEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHCCCCHHHHHHH
TAGAAGYDLSALASRVTQNSRHTAPAVDARHDIVIVGAGAAGIAVASSLLARDASLDIAV
HCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEE
IDPADVHYYQPGWTMVGAGVFQAGTTARPMTDVLPRGVHRIRAAVTGFEPDAHVVVLDGC
ECCCCCEEECCCCEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
RRIGYRKLVVCPGLKLDWHAIDGLADTLGHNGVTSNYRYDLAPYTWELVRAFRGGNALFT
HHCCCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEE
QPPMPIKCAGAPQKAMYLSCDHWRRTGRLGAANVEFLNAGGALFGVADYVPALMEYVKSY
CCCCCEEECCCCCCEEEEECHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
DIALSFGHNLVAIDGPARRATFSRALPDGGKATVERSFDMIHVVPPQKAPDFVRASPLVD
CEEEECCCEEEEECCCHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCHHCCCCCC
AAGWIDVDPATLRHKQFEDIYALGDVTNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDA
CCCCEECCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCC
AYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWK
CCCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
AMLKGREWLAKPAIAR
HHHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]