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The map label for this gene is blh [H]

Identifier: 116689766

GI number: 116689766

Start: 1940771

End: 1941655

Strand: Direct

Name: blh [H]

Synonym: Bcen2424_1745

Alternate gene names: 116689766

Gene position: 1940771-1941655 (Clockwise)

Preceding gene: 116689763

Following gene: 116689767

Centisome position: 55.71

GC content: 70.17

Gene sequence:

>885_bases
GTGAGCAACGCCCCCGCCCTGTCGGTCGAAGGTTTTTTCGACCCGGCGACCCACACCGTCAGCTATCTCCTGCTCGATAC
GGCGAGCCGCGCGTGCGCGCTGATCGACAGCGTGCTCGACTACGACCCGAAATCCGGCCGCACGCGCACCGCGAGCGCCG
ACCGGCTGATCGCGCGCGTCGCCGAACTCGGCGCGACCGTGCACTGGCTGCTGGAGACGCACGTGCACGCCGACCACCTG
TCGGCCGCGCCCTACCTGAAAGCACGGGTCGGCGGCCAGATCGCAATCGGTTCGCACGTGCGCCGCGTGCAGCACGTATT
CGGCACGCTGTTCAACGCAGGGCCGGGCTTTGCGGAAGACAGCCGCCAGTTCGACCGGCTCGTCGACGACGGCGACACGC
TCGCGCTCGGCGCGCTGACGATCCGCGCGCTGCACACGCCGGGCCACACGCCCGCGTGCATGACCTACTGCGTCGACGAT
GCGACGCAGCGCGCGGCGTTCGTCGGCGACACGCTGTTCATGCCCGACTACGGCACGGCCCGCTGCGACTTCCCCGGCGG
CGACGCGCGCACGCTGTACCGCTCGATCGCGCGGGTGCTCGCGCTGCCGCCCGACACGCGACTGTTCCTGTGCCACGACT
ACCAGCCGGGCGGCCGCGACGTGCAGTTCGTGACGACCGTCGCCGAGCAGCGCCGTGCGAACGTGCACGTGAAGGACGGC
GTGACCGAGGACGATTTCGTCGCGATGCGCACCGCGCGCGACGCGACGCTCGACATGCCGGTGCTGATGCTGCCGTCCGT
ACAGGTCAACATGCGCGCCGGCCACCTGCCCGAACCCGAGAACAACGGCGTGCGCTACCTGAAGATTCCGCTCGACGCGA
TCTGA

Upstream 100 bases:

>100_bases
TCAAGCCCCTGCCACATCGGCGGATGCTGCACCGCAGACTGGCACGCTTCTTGAAGTAAAGATCCCGATTGCAGATGCAG
AACCCGATCGAGGACACTCC

Downstream 100 bases:

>100_bases
GCGCCCGAACCCCACCGAGAACTCCGACATGACCACCCTCCGCAAGCTGACCGACGCGCTGTCGGTCTCGCCGCAGATCG
CGGCGGCCGACCTGCCCGCG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSNAPALSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHL
SAAPYLKARVGGQIAIGSHVRRVQHVFGTLFNAGPGFAEDSRQFDRLVDDGDTLALGALTIRALHTPGHTPACMTYCVDD
ATQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLFLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
VTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Sequences:

>Translated_294_residues
MSNAPALSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHL
SAAPYLKARVGGQIAIGSHVRRVQHVFGTLFNAGPGFAEDSRQFDRLVDDGDTLALGALTIRALHTPGHTPACMTYCVDD
ATQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLFLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
VTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
>Mature_293_residues
SNAPALSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARVAELGATVHWLLETHVHADHLS
AAPYLKARVGGQIAIGSHVRRVQHVFGTLFNAGPGFAEDSRQFDRLVDDGDTLALGALTIRALHTPGHTPACMTYCVDDA
TQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLFLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGV
TEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=274, Percent_Identity=30.6569343065693, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1787158, Length=170, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=273, Percent_Identity=27.8388278388278, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221330176, Length=272, Percent_Identity=29.4117647058824, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32024; Mature: 31892

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAPALSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARV
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
AELGATVHWLLETHVHADHLSAAPYLKARVGGQIAIGSHVRRVQHVFGTLFNAGPGFAED
HHHCCHHEEHHHHHHCHHHHCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHH
SRQFDRLVDDGDTLALGALTIRALHTPGHTPACMTYCVDDATQRAAFVGDTLFMPDYGTA
HHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCE
RCDFPGGDARTLYRSIARVLALPPDTRLFLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECC
VTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
CCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SNAPALSVEGFFDPATHTVSYLLLDTASRACALIDSVLDYDPKSGRTRTASADRLIARV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
AELGATVHWLLETHVHADHLSAAPYLKARVGGQIAIGSHVRRVQHVFGTLFNAGPGFAED
HHHCCHHEEHHHHHHCHHHHCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHH
SRQFDRLVDDGDTLALGALTIRALHTPGHTPACMTYCVDDATQRAAFVGDTLFMPDYGTA
HHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCE
RCDFPGGDARTLYRSIARVLALPPDTRLFLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECC
VTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
CCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]