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The map label for this gene is echA8 [H]

Identifier: 116689582

GI number: 116689582

Start: 1724996

End: 1726159

Strand: Direct

Name: echA8 [H]

Synonym: Bcen2424_1560

Alternate gene names: 116689582

Gene position: 1724996-1726159 (Clockwise)

Preceding gene: 116689581

Following gene: 116689584

Centisome position: 49.51

GC content: 69.67

Gene sequence:

>1164_bases
ATGACCTTCATGACCGATTCCCTTTCCGCCGCCGTTTCCGCCGAATCCGCCCAGCCCGACGTGCGCGCCTATGTCGCGAA
CCGCATCGGCTTTCTCGAACTGAACCGGCCGAAGGCGCTGAATGCGCTGTCGATCGGCATGATCCGGCTGATGCAGCAGG
CGCTCGACGCGTGGCGCGACGATCCCGACGTCGTCGCGGTCGTGGTGCACAGTCCCCACCCGCGCGCGTTCTGCGCGGGC
GGCGACGTGCGCTTCTTCCACGATGCGTGGCAGCGCGGCGACCGCGATGCGGTCGATACGTTCTTCATCGAGGAATACAC
GCTGAACCATGCGATTTTCACGTATCCGAAGCCGTACATCGCGTTGATGCACGGCGTCGTGATGGGCGGCGGCATGGGGA
TTTCGCAGGCGGCGCGGCATACGGGCGGCCTGCGCGTCGTGACCGACTCGACGAAGATGGCGATGCCCGAAACGCGCATC
GGCCTGTTCCCGGACGTCGGGATGAGCTGGTTTCTCGCGCGCACGCCCGGCGCGATCGGCCGCTATCTCGCGGTGACCGG
CGCGACGCTCGACGCGGCCGGCGCGCTGTACGCGCAACTCGCCGACGTCTATCTGCCCGATGCCGCGCTGCCGCCGCTGC
TCGACACGCTGCGCGGCACGCGCATCGACAGCGGTGCGCAGGCCGTCGGGTGCGTGACCGACGCGGCGGCCGCGCACAAG
GTCGTGCCGACGCCGGACACGTCGGCGCTCGCCGACGCGCGCGCCGGGATCGACCGGCATTTCGCGCAGCCCGACCTCAA
CGCAATCCTCGCGTCGCTCGACGCCGAGCCGGATTGCGCGGCGGTCGACGGGTGGGTCGAGAAGGCGACTCACGCGATGC
GCGAGCAGTTGTCGCCGCTGTCGATGGCCGTATCGCTCGAAGTCGTCGAACGCGCGCGCGGCGCGACGATGGCCGATTGC
CTGCGGCGCGATCTCGATCTCACGCGCTCGACCTTCGCGCGCGGCGACGTGATCGAAGGCGTGCGCGCGCTGATCGTCGA
CAAGGATCACCAGCCGGTGTGGCGCTTCAGGTCGGCCGCCGACGTCGGGCGCGCCGACGTGCTCGCGATGTTCGACAGCC
CGTGGACGCCCGACACGCATCCGCTGCGCGCGCTGAAGGACTGA

Upstream 100 bases:

>100_bases
CCGGCGGTGATCGGCCTCGGGCTGATCATCGCGGGCGTCGTGGTGCTGAACCTGTTCTCGAAGATGCAGGCGCACTGAGC
GTGCGACCGCCGTTTGCCGG

Downstream 100 bases:

>100_bases
CGTCGATCAGGCTGATTCGCGCGGGAGGAGCGACGCGCGGGGAAGAAACGAAAAGGCCGCGTGCACGATGCACGCGGCCT
TTTTCATGGATGTCGGCCGG

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTFMTDSLSAAVSAESAQPDVRAYVANRIGFLELNRPKALNALSIGMIRLMQQALDAWRDDPDVVAVVVHSPHPRAFCAG
GDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRI
GLFPDVGMSWFLARTPGAIGRYLAVTGATLDAAGALYAQLADVYLPDAALPPLLDTLRGTRIDSGAQAVGCVTDAAAAHK
VVPTPDTSALADARAGIDRHFAQPDLNAILASLDAEPDCAAVDGWVEKATHAMREQLSPLSMAVSLEVVERARGATMADC
LRRDLDLTRSTFARGDVIEGVRALIVDKDHQPVWRFRSAADVGRADVLAMFDSPWTPDTHPLRALKD

Sequences:

>Translated_387_residues
MTFMTDSLSAAVSAESAQPDVRAYVANRIGFLELNRPKALNALSIGMIRLMQQALDAWRDDPDVVAVVVHSPHPRAFCAG
GDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRI
GLFPDVGMSWFLARTPGAIGRYLAVTGATLDAAGALYAQLADVYLPDAALPPLLDTLRGTRIDSGAQAVGCVTDAAAAHK
VVPTPDTSALADARAGIDRHFAQPDLNAILASLDAEPDCAAVDGWVEKATHAMREQLSPLSMAVSLEVVERARGATMADC
LRRDLDLTRSTFARGDVIEGVRALIVDKDHQPVWRFRSAADVGRADVLAMFDSPWTPDTHPLRALKD
>Mature_386_residues
TFMTDSLSAAVSAESAQPDVRAYVANRIGFLELNRPKALNALSIGMIRLMQQALDAWRDDPDVVAVVVHSPHPRAFCAGG
DVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIG
LFPDVGMSWFLARTPGAIGRYLAVTGATLDAAGALYAQLADVYLPDAALPPLLDTLRGTRIDSGAQAVGCVTDAAAAHKV
VPTPDTSALADARAGIDRHFAQPDLNAILASLDAEPDCAAVDGWVEKATHAMREQLSPLSMAVSLEVVERARGATMADCL
RRDLDLTRSTFARGDVIEGVRALIVDKDHQPVWRFRSAADVGRADVLAMFDSPWTPDTHPLRALKD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=349, Percent_Identity=31.5186246418338, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI37594469, Length=301, Percent_Identity=31.2292358803987, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI194097323, Length=221, Percent_Identity=29.8642533936652, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=386, Percent_Identity=36.5284974093264, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI25144160, Length=386, Percent_Identity=36.5284974093264, Blast_Score=194, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320241, Length=198, Percent_Identity=37.3737373737374, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28571730, Length=386, Percent_Identity=33.9378238341969, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28571729, Length=386, Percent_Identity=33.9378238341969, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=28.9795918367347, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 41761; Mature: 41630

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFMTDSLSAAVSAESAQPDVRAYVANRIGFLELNRPKALNALSIGMIRLMQQALDAWRD
CCCCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DPDVVAVVVHSPHPRAFCAGGDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYI
CCCEEEEEEECCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHH
ALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGAIG
HHHHHHHHCCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCCCEEECCCCCHHH
RYLAVTGATLDAAGALYAQLADVYLPDAALPPLLDTLRGTRIDSGAQAVGCVTDAAAAHK
HHHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
VVPTPDTSALADARAGIDRHFAQPDLNAILASLDAEPDCAAVDGWVEKATHAMREQLSPL
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHH
SMAVSLEVVERARGATMADCLRRDLDLTRSTFARGDVIEGVRALIVDKDHQPVWRFRSAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCHHHHHHHHH
DVGRADVLAMFDSPWTPDTHPLRALKD
HCCCHHEEEEECCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TFMTDSLSAAVSAESAQPDVRAYVANRIGFLELNRPKALNALSIGMIRLMQQALDAWRD
CCCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DPDVVAVVVHSPHPRAFCAGGDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYI
CCCEEEEEEECCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHH
ALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGAIG
HHHHHHHHCCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCCCEEECCCCCHHH
RYLAVTGATLDAAGALYAQLADVYLPDAALPPLLDTLRGTRIDSGAQAVGCVTDAAAAHK
HHHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
VVPTPDTSALADARAGIDRHFAQPDLNAILASLDAEPDCAAVDGWVEKATHAMREQLSPL
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHH
SMAVSLEVVERARGATMADCLRRDLDLTRSTFARGDVIEGVRALIVDKDHQPVWRFRSAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCHHHHHHHHH
DVGRADVLAMFDSPWTPDTHPLRALKD
HCCCHHEEEEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]