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The map label for this gene is ppe63 [H]

Identifier: 108797228

GI number: 108797228

Start: 289529

End: 290662

Strand: Direct

Name: ppe63 [H]

Synonym: Mmcs_0248

Alternate gene names: 108797228

Gene position: 289529-290662 (Clockwise)

Preceding gene: 108797227

Following gene: 108797230

Centisome position: 5.07

GC content: 69.4

Gene sequence:

>1134_bases
ATGAGACGGCTTCTCGCATTCGGTTCTGCGCTGACGATCATCGGCGCCGCAGGCGGTTTCGGCTTCGGCAGCGCGTCGGC
CGACGAGCCACCGGTCCCGCCGCCGCCCGCCCCGGCCGACGGTCCGCCGCCGCTGGGCACACCGGGTAGGGCCTACGCCC
TCGGCGGTGCGCACGTGCTGGGCATCCCCTACGACGAATACATCATGCGCACCGGCTCGGACTGGTTCCCGGGTCTGGAC
CGGCAGATCGTCGACTACCCGGCCGGGCAGGTCCAGGGGCACACTCTCGAGCGGCTGTTCCCCGGTATCGGCCGGTTGGA
CGACTCCTTCCCCGGACTGGGCATCGACGGTCCCAGCGTCGGTGAGTCGGTCGACGTCGGCACACCGAACGTCATCAACG
CCGTCCGGGAGGGTGGTCGCGGTACCGCGATCGGCCTGTCCGAGGGTGCGATGGTGCTCAACGACGTGCAGGCGAAGCTG
GCCTACGACCCGGCCGCCCCGCCCCCGGACGAGTTGAGCTTCGCGATGTACGGCGACCCGGTGGCCCGGCACGCCTTCGG
CGAGAGCTTCCTGACCCAGAACTTCCCCGTCGGCAGCGTCGTGCCGTCACTCGACTACCGGATCCCGGCGCCGGTGGAGA
GCCAGTACGACACCTACCACTTCGTCTCCGCGTACGACAGCATCGCCGACTGGCCGGACCGGCCGGACAACTGGATCTCC
GTCGCCAATGCGATCGTGGGCCTGGCGACCGGTCACACCGCGGTCGCCTTCACCGAACCGAGCATGGTGCCGGAGCGCAA
CATCCGGACCACCGTCAACTCCCGCGGCGCGAAGACCACCACGTTCATGATCCCCGAGGAGCACCTCCCGCTGGTGCTGC
CGTTCAAGTACCTCGGGGTGCCCAAGGACACGCTGATGGAACTCGACTCGGTGCTCAAGCCGTACGTGGACGCGGGCTAC
TCCCGCAACGACGATCCGCTGACCGCCCCGATCACCGTGGACCCGGTGAACGGTTACGACCCCGCGGAGGTCACCGCGCC
GGCGACGCAGGCCGCCTTCGGCGGCGCCGCCGATCCGGTGTCGCAGCTGTTGTCGGGACTCCAGTACGTCCTGAACAACC
AGCCGACCGGGTGA

Upstream 100 bases:

>100_bases
TTCGCCCGGCTCGACGGCGGGAAGGGGCAGCATGGGCACCTGGCGGGGTAATGTCGGGCCCGGTGCGGCCGAGCAGGGCG
GGAAGGTGCGCGAAACGATT

Downstream 100 bases:

>100_bases
TTTCGGCGTGCTTGGTCGCGGTGAGCGCGACTGCGCACGCCGAAATCGCTACAGACCCGCGAAGCCGACGCCGAGCAGCA
CGCAGCCGATCACGGCCAGC

Product: PE-PPE-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRRLLAFGSALTIIGAAGGFGFGSASADEPPVPPPPAPADGPPPLGTPGRAYALGGAHVLGIPYDEYIMRTGSDWFPGLD
RQIVDYPAGQVQGHTLERLFPGIGRLDDSFPGLGIDGPSVGESVDVGTPNVINAVREGGRGTAIGLSEGAMVLNDVQAKL
AYDPAAPPPDELSFAMYGDPVARHAFGESFLTQNFPVGSVVPSLDYRIPAPVESQYDTYHFVSAYDSIADWPDRPDNWIS
VANAIVGLATGHTAVAFTEPSMVPERNIRTTVNSRGAKTTTFMIPEEHLPLVLPFKYLGVPKDTLMELDSVLKPYVDAGY
SRNDDPLTAPITVDPVNGYDPAEVTAPATQAAFGGAADPVSQLLSGLQYVLNNQPTG

Sequences:

>Translated_377_residues
MRRLLAFGSALTIIGAAGGFGFGSASADEPPVPPPPAPADGPPPLGTPGRAYALGGAHVLGIPYDEYIMRTGSDWFPGLD
RQIVDYPAGQVQGHTLERLFPGIGRLDDSFPGLGIDGPSVGESVDVGTPNVINAVREGGRGTAIGLSEGAMVLNDVQAKL
AYDPAAPPPDELSFAMYGDPVARHAFGESFLTQNFPVGSVVPSLDYRIPAPVESQYDTYHFVSAYDSIADWPDRPDNWIS
VANAIVGLATGHTAVAFTEPSMVPERNIRTTVNSRGAKTTTFMIPEEHLPLVLPFKYLGVPKDTLMELDSVLKPYVDAGY
SRNDDPLTAPITVDPVNGYDPAEVTAPATQAAFGGAADPVSQLLSGLQYVLNNQPTG
>Mature_377_residues
MRRLLAFGSALTIIGAAGGFGFGSASADEPPVPPPPAPADGPPPLGTPGRAYALGGAHVLGIPYDEYIMRTGSDWFPGLD
RQIVDYPAGQVQGHTLERLFPGIGRLDDSFPGLGIDGPSVGESVDVGTPNVINAVREGGRGTAIGLSEGAMVLNDVQAKL
AYDPAAPPPDELSFAMYGDPVARHAFGESFLTQNFPVGSVVPSLDYRIPAPVESQYDTYHFVSAYDSIADWPDRPDNWIS
VANAIVGLATGHTAVAFTEPSMVPERNIRTTVNSRGAKTTTFMIPEEHLPLVLPFKYLGVPKDTLMELDSVLKPYVDAGY
SRNDDPLTAPITVDPVNGYDPAEVTAPATQAAFGGAADPVSQLLSGLQYVLNNQPTG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 39700; Mature: 39700

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLAFGSALTIIGAAGGFGFGSASADEPPVPPPPAPADGPPPLGTPGRAYALGGAHVL
CCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEE
GIPYDEYIMRTGSDWFPGLDRQIVDYPAGQVQGHTLERLFPGIGRLDDSFPGLGIDGPSV
CCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
GESVDVGTPNVINAVREGGRGTAIGLSEGAMVLNDVQAKLAYDPAAPPPDELSFAMYGDP
CCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCH
VARHAFGESFLTQNFPVGSVVPSLDYRIPAPVESQYDTYHFVSAYDSIADWPDRPDNWIS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
VANAIVGLATGHTAVAFTEPSMVPERNIRTTVNSRGAKTTTFMIPEEHLPLVLPFKYLGV
HHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCEEECHHHHCC
PKDTLMELDSVLKPYVDAGYSRNDDPLTAPITVDPVNGYDPAEVTAPATQAAFGGAADPV
CHHHHHHHHHHHHHHHHCCCCCCCCCEECCEEECCCCCCCCCCCCCCHHHHHCCCCHHHH
SQLLSGLQYVLNNQPTG
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRRLLAFGSALTIIGAAGGFGFGSASADEPPVPPPPAPADGPPPLGTPGRAYALGGAHVL
CCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEE
GIPYDEYIMRTGSDWFPGLDRQIVDYPAGQVQGHTLERLFPGIGRLDDSFPGLGIDGPSV
CCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
GESVDVGTPNVINAVREGGRGTAIGLSEGAMVLNDVQAKLAYDPAAPPPDELSFAMYGDP
CCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCH
VARHAFGESFLTQNFPVGSVVPSLDYRIPAPVESQYDTYHFVSAYDSIADWPDRPDNWIS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
VANAIVGLATGHTAVAFTEPSMVPERNIRTTVNSRGAKTTTFMIPEEHLPLVLPFKYLGV
HHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCEEECHHHHCC
PKDTLMELDSVLKPYVDAGYSRNDDPLTAPITVDPVNGYDPAEVTAPATQAAFGGAADPV
CHHHHHHHHHHHHHHHHCCCCCCCCCEECCEEECCCCCCCCCCCCCCHHHHHCCCCHHHH
SQLLSGLQYVLNNQPTG
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]