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The map label for this gene is hsaB [H]

Identifier: 108797230

GI number: 108797230

Start: 291481

End: 291966

Strand: Direct

Name: hsaB [H]

Synonym: Mmcs_0250

Alternate gene names: 108797230

Gene position: 291481-291966 (Clockwise)

Preceding gene: 108797228

Following gene: 108797236

Centisome position: 5.11

GC content: 67.9

Gene sequence:

>486_bases
ATGAGCGCAATCGATCTGAACCCGGCCACGCTGCGCGAGGCCTTCGGTCACTTCCCGACCGGTGTCATCGCGATCGCGGC
GGAGGTCGACGGCATTCGCGTCGGCCTGGCCGCGAGCACCTTCGTCCCGGTGTCCCTCGACCCACCGCTGGTGTCGTTCT
GCGTCCAGAACACCTCGACGACGTGGCCGAAACTCAAGGATCTGCCCCGCCTGGGCATCAGCGTGCTGGGCGAATCGCAC
GACGCGGCCGCGCGCACGCTGGCGGCCAAGGCCGGTGACCGGTTCGCCGGGCTGGAGACGACGTCGACCGACGAAGGTGC
GGTGTTCATCCACGGCACCAGCGTGTGGTTGGACAGTTCGGTGCACGACCTCGTCGAGGCGGGCGATCACACCATCGTCA
TCCTGCGCGTCGAGGACATCACCGTCCACCCCGACGTCGCACCGATCGTGTTCCACCGCAGCACCTTCCACCGTCTCGGC
GGGTGA

Upstream 100 bases:

>100_bases
ATGAGCGTCAGGCTACCGCCCCGGGGGCGCCGCGCCGGTTTCCGCTCACCGGGACTCAGACCATGGCTCCTCGCCGACGC
CCGTGTGAAGATGGACGGCG

Downstream 100 bases:

>100_bases
CGCGACGGGGTCTAGGGGCGCTGGGCGAGTTCCTCGCGATAACCCTGGATCCGCCGCTCGATCTCGGCGGCATCGCTGGG
CCGGCCCTGCTTGCGGGCCA

Product: flavin reductase-like, FMN-binding protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSAIDLNPATLREAFGHFPTGVIAIAAEVDGIRVGLAASTFVPVSLDPPLVSFCVQNTSTTWPKLKDLPRLGISVLGESH
DAAARTLAAKAGDRFAGLETTSTDEGAVFIHGTSVWLDSSVHDLVEAGDHTIVILRVEDITVHPDVAPIVFHRSTFHRLG
G

Sequences:

>Translated_161_residues
MSAIDLNPATLREAFGHFPTGVIAIAAEVDGIRVGLAASTFVPVSLDPPLVSFCVQNTSTTWPKLKDLPRLGISVLGESH
DAAARTLAAKAGDRFAGLETTSTDEGAVFIHGTSVWLDSSVHDLVEAGDHTIVILRVEDITVHPDVAPIVFHRSTFHRLG
G
>Mature_160_residues
SAIDLNPATLREAFGHFPTGVIAIAAEVDGIRVGLAASTFVPVSLDPPLVSFCVQNTSTTWPKLKDLPRLGISVLGESHD
AAARTLAAKAGDRFAGLETTSTDEGAVFIHGTSVWLDSSVHDLVEAGDHTIVILRVEDITVHPDVAPIVFHRSTFHRLGG

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 17044; Mature: 16913

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIDLNPATLREAFGHFPTGVIAIAAEVDGIRVGLAASTFVPVSLDPPLVSFCVQNTST
CCCCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECEEEEEECCCHHHHHHHCCCCC
TWPKLKDLPRLGISVLGESHDAAARTLAAKAGDRFAGLETTSTDEGAVFIHGTSVWLDSS
CCCCHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECEEEECCH
VHDLVEAGDHTIVILRVEDITVHPDVAPIVFHRSTFHRLGG
HHHHHHCCCCEEEEEEEECEEECCCCCEEEEECHHHHHCCC
>Mature Secondary Structure 
SAIDLNPATLREAFGHFPTGVIAIAAEVDGIRVGLAASTFVPVSLDPPLVSFCVQNTST
CCCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECEEEEEECCCHHHHHHHCCCCC
TWPKLKDLPRLGISVLGESHDAAARTLAAKAGDRFAGLETTSTDEGAVFIHGTSVWLDSS
CCCCHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECEEEECCH
VHDLVEAGDHTIVILRVEDITVHPDVAPIVFHRSTFHRLGG
HHHHHHCCCCEEEEEEEECEEECCCCCEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]