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The map label for this gene is xseA [H]

Identifier: 239617914

GI number: 239617914

Start: 1651895

End: 1653424

Strand: Reverse

Name: xseA [H]

Synonym: Kole_1542

Alternate gene names: 239617914

Gene position: 1653424-1651895 (Counterclockwise)

Preceding gene: 239617918

Following gene: 239617913

Centisome position: 71.82

GC content: 42.68

Gene sequence:

>1530_bases
ATGAAGAGATTTAAGGGCGTCTCTGAATTAATGAGATGGATACGGGATTTTTCAGAGGAGTACTTCTCTGAACCCGTTGA
GTTTTTTGGGGAAGTACGCGATGCAAGAGTAAACAGAAGAAATGTTTTGAACATAGAAGTGGTGGAAACTGTTAAAGGAT
ACAGAAGCGGAAGCTTTACGTACCAGATCCCATGTCAGATAGATTACCCGGAGAGTATCCTCGATGAACTTGGCATTGAA
AGTTATAAAGAAATGGAGGGTGAGCTTTACAGTGTCATTGGAAAGCTCGTTTTTCGTGTTACTCAAAATCGGTACGTTGT
GGAAGTCATCAAGATTGAACCCTACGGAAAAGGTGCCATCGAAAAACGCAGGCAAAAGATCCTCGAGAAACTGAGATCCG
AAGGGCTCTATCCGGTAAAACAACTGTCCTCTCTCCTTGAACTTGGCGAACCCATACTTGACATAGCCATCCTGGCTTCG
CCAAACACCCGGGGGCTTTCCGATTTTCTAAGAATGCTCCAGGATTCCCCTTTAATCCCTGATTTTACATATTACCCAAT
TTCAATTGAGGGGGCAAGCGCAGCAAAAGAACTCGTTTCAGCTCTTGGTAAGGCCAACAATAGGGCCCATCAACTGATCG
TCATCGTCAGGGGCGGTGGCGCTCAGGGAGGGTTACTTTATCTCGATGACGAATCACTAGCAAGAGCCGTCGCTTCCTCA
AAACTCCCGGTAATTGTAGGGATCGGTCATTCTGAAGATAAAACCCTGCTCGACTATGTCGCAAGTATGTCCTTTGAAAC
CCCGACAGCGGTCGGAAGAGAGATATCGCAGATCAACCGGGATTATATTCACTCCCTATCTGAACTGGAAGAAAAGCTGG
ATTCAGTTTTTTCGGAACTCTTATCTTCTTTTGTTAGCAATATCCAGTCCCGTTCAAGGATTCTTAGTGCTTACAGTATC
GAGAGAATGATAAAATTCGACCACCAAAAACTTCTATCCTTTGTTCGTAGGTTGAACAGGATAGATTTTCTGACAGACAA
TATGAAAGAAGCTTTGAACCGTTCACGTAAGAATTTAATTTCAAATTCCGCGAATATCATGAACGAAAAAACAAAATGGT
TCTGGCTCAATTTAAAAGAATTCAGACGCCATGAAAACGAACTATCAAGCAGGATTAAAAACTTCGAAGAAAGGATCACA
CCGGAAATCATCGATCTCGAGAGGTTTTTGATGGAAAAAAGCAGGGATTTCAAGAAACTCACCGGATACTTCAGCAGCAA
TGCCAAAAGCTTTTACCGCTGGCAACGCGAAAGATTGCAGCGATACATAGCCGAGATTCGATCAATAAACCCAATATACG
CTTTAGTAAAAGGCGGCGCCATTGTAATGGACGAAGAAGGAAAGGCTATCGTATCCATTGAAGATGTTAAAATAGGCGAT
GAGGTTCTTATAAGACTTTCAGATGGTTCTCTGCGTTCCGAAATCCTCGAAAAGATCACCACAAAGAAAAAAAATTTAGT
AAAGGAGTGA

Upstream 100 bases:

>100_bases
ATAATCCTGAACACACCAAACACCTCCATATCTTCTTCTAAGGATATTTTACATCACTCAACCTCCTTATGTGATAACAT
TGTTTTGGAGGTTCGATGAC

Downstream 100 bases:

>100_bases
AAATAACATGCTTCCGCAGGATATAAATGAACTTGACCTGAAAGGATTCAAAGATTTTCTGGAAACCCTCACGGAAGAAG
AAATGAAAGAACTTCGCTTC

Product: Exodeoxyribonuclease VII

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MKRFKGVSELMRWIRDFSEEYFSEPVEFFGEVRDARVNRRNVLNIEVVETVKGYRSGSFTYQIPCQIDYPESILDELGIE
SYKEMEGELYSVIGKLVFRVTQNRYVVEVIKIEPYGKGAIEKRRQKILEKLRSEGLYPVKQLSSLLELGEPILDIAILAS
PNTRGLSDFLRMLQDSPLIPDFTYYPISIEGASAAKELVSALGKANNRAHQLIVIVRGGGAQGGLLYLDDESLARAVASS
KLPVIVGIGHSEDKTLLDYVASMSFETPTAVGREISQINRDYIHSLSELEEKLDSVFSELLSSFVSNIQSRSRILSAYSI
ERMIKFDHQKLLSFVRRLNRIDFLTDNMKEALNRSRKNLISNSANIMNEKTKWFWLNLKEFRRHENELSSRIKNFEERIT
PEIIDLERFLMEKSRDFKKLTGYFSSNAKSFYRWQRERLQRYIAEIRSINPIYALVKGGAIVMDEEGKAIVSIEDVKIGD
EVLIRLSDGSLRSEILEKITTKKKNLVKE

Sequences:

>Translated_509_residues
MKRFKGVSELMRWIRDFSEEYFSEPVEFFGEVRDARVNRRNVLNIEVVETVKGYRSGSFTYQIPCQIDYPESILDELGIE
SYKEMEGELYSVIGKLVFRVTQNRYVVEVIKIEPYGKGAIEKRRQKILEKLRSEGLYPVKQLSSLLELGEPILDIAILAS
PNTRGLSDFLRMLQDSPLIPDFTYYPISIEGASAAKELVSALGKANNRAHQLIVIVRGGGAQGGLLYLDDESLARAVASS
KLPVIVGIGHSEDKTLLDYVASMSFETPTAVGREISQINRDYIHSLSELEEKLDSVFSELLSSFVSNIQSRSRILSAYSI
ERMIKFDHQKLLSFVRRLNRIDFLTDNMKEALNRSRKNLISNSANIMNEKTKWFWLNLKEFRRHENELSSRIKNFEERIT
PEIIDLERFLMEKSRDFKKLTGYFSSNAKSFYRWQRERLQRYIAEIRSINPIYALVKGGAIVMDEEGKAIVSIEDVKIGD
EVLIRLSDGSLRSEILEKITTKKKNLVKE
>Mature_509_residues
MKRFKGVSELMRWIRDFSEEYFSEPVEFFGEVRDARVNRRNVLNIEVVETVKGYRSGSFTYQIPCQIDYPESILDELGIE
SYKEMEGELYSVIGKLVFRVTQNRYVVEVIKIEPYGKGAIEKRRQKILEKLRSEGLYPVKQLSSLLELGEPILDIAILAS
PNTRGLSDFLRMLQDSPLIPDFTYYPISIEGASAAKELVSALGKANNRAHQLIVIVRGGGAQGGLLYLDDESLARAVASS
KLPVIVGIGHSEDKTLLDYVASMSFETPTAVGREISQINRDYIHSLSELEEKLDSVFSELLSSFVSNIQSRSRILSAYSI
ERMIKFDHQKLLSFVRRLNRIDFLTDNMKEALNRSRKNLISNSANIMNEKTKWFWLNLKEFRRHENELSSRIKNFEERIT
PEIIDLERFLMEKSRDFKKLTGYFSSNAKSFYRWQRERLQRYIAEIRSINPIYALVKGGAIVMDEEGKAIVSIEDVKIGD
EVLIRLSDGSLRSEILEKITTKKKNLVKE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=417, Percent_Identity=21.8225419664269, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 58549; Mature: 58549

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFKGVSELMRWIRDFSEEYFSEPVEFFGEVRDARVNRRNVLNIEVVETVKGYRSGSFT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCEE
YQIPCQIDYPESILDELGIESYKEMEGELYSVIGKLVFRVTQNRYVVEVIKIEPYGKGAI
EEECEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHH
EKRRQKILEKLRSEGLYPVKQLSSLLELGEPILDIAILASPNTRGLSDFLRMLQDSPLIP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHCCCCCCC
DFTYYPISIEGASAAKELVSALGKANNRAHQLIVIVRGGGAQGGLLYLDDESLARAVASS
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHCC
KLPVIVGIGHSEDKTLLDYVASMSFETPTAVGREISQINRDYIHSLSELEEKLDSVFSEL
CCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSFVSNIQSRSRILSAYSIERMIKFDHQKLLSFVRRLNRIDFLTDNMKEALNRSRKNLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNSANIMNEKTKWFWLNLKEFRRHENELSSRIKNFEERITPEIIDLERFLMEKSRDFKKL
HCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
TGYFSSNAKSFYRWQRERLQRYIAEIRSINPIYALVKGGAIVMDEEGKAIVSIEDVKIGD
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCEEEEEECEECCC
EVLIRLSDGSLRSEILEKITTKKKNLVKE
HHEEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRFKGVSELMRWIRDFSEEYFSEPVEFFGEVRDARVNRRNVLNIEVVETVKGYRSGSFT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCEE
YQIPCQIDYPESILDELGIESYKEMEGELYSVIGKLVFRVTQNRYVVEVIKIEPYGKGAI
EEECEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHH
EKRRQKILEKLRSEGLYPVKQLSSLLELGEPILDIAILASPNTRGLSDFLRMLQDSPLIP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHCCCCCCC
DFTYYPISIEGASAAKELVSALGKANNRAHQLIVIVRGGGAQGGLLYLDDESLARAVASS
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHCC
KLPVIVGIGHSEDKTLLDYVASMSFETPTAVGREISQINRDYIHSLSELEEKLDSVFSEL
CCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSFVSNIQSRSRILSAYSIERMIKFDHQKLLSFVRRLNRIDFLTDNMKEALNRSRKNLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNSANIMNEKTKWFWLNLKEFRRHENELSSRIKNFEERITPEIIDLERFLMEKSRDFKKL
HCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
TGYFSSNAKSFYRWQRERLQRYIAEIRSINPIYALVKGGAIVMDEEGKAIVSIEDVKIGD
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCEEEEEECEECCC
EVLIRLSDGSLRSEILEKITTKKKNLVKE
HHEEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA