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The map label for this gene is fur [H]

Identifier: 239617900

GI number: 239617900

Start: 1640580

End: 1641026

Strand: Reverse

Name: fur [H]

Synonym: Kole_1528

Alternate gene names: 239617900

Gene position: 1641026-1640580 (Counterclockwise)

Preceding gene: 239617901

Following gene: 239617897

Centisome position: 71.28

GC content: 42.95

Gene sequence:

>447_bases
GTGAAGCAAGACATTCTTAGAAGTGAGTTGCGCAAGAGAAAACAAAGAATGACCGCCCAAAGAGAGTTGATATTGAAAGC
TTTCATGGAATCCGGAGAAGAACATATGAGCGCCGAGGAAGTCTACAGAAAGGTGCTTGAAAGAAGGCTTCGAATAAGTA
AGGCTACGGTTTACAGAACGGTGGAACTTTTAACGGAGGTAGGCCTTCTCAGAAAAATCGTTTTTCGTGATGGTGTGGTT
CGTTACGAGCTCGTCGATAAAGGTGAACATCATCACCACCACCTGGTATGTAACAGCTGCGGTAAGGTTATCGAATTTCC
GGAAGATCTTCTCGATGGTCTTGAGAATCTCATAGAGGAAAAAACCGGTTTCAAAATAACCGACCACCAACTTAAGTTTT
ACGGGCTTTGCTCTGAATGCCAGAAGAGTATTGCAAACAAAGAATAA

Upstream 100 bases:

>100_bases
GATATTTTGTAACATATTACCTACTCTCTGTAAATGAACTCATGTAAAATGAATCTGATGATCCTTATTCACCAACAGTT
TTGGCAGGGAGGTTTTGAAA

Downstream 100 bases:

>100_bases
GAGACTAACAACGCCACAAAATAAGACCACGGAAAAGGTACAGTTACTATCAGTCCAAGCTCTGAAATTTTGTGAAGCCC
TTTTTCAAAAAACAAAGACA

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKQDILRSELRKRKQRMTAQRELILKAFMESGEEHMSAEEVYRKVLERRLRISKATVYRTVELLTEVGLLRKIVFRDGVV
RYELVDKGEHHHHHLVCNSCGKVIEFPEDLLDGLENLIEEKTGFKITDHQLKFYGLCSECQKSIANKE

Sequences:

>Translated_148_residues
MKQDILRSELRKRKQRMTAQRELILKAFMESGEEHMSAEEVYRKVLERRLRISKATVYRTVELLTEVGLLRKIVFRDGVV
RYELVDKGEHHHHHLVCNSCGKVIEFPEDLLDGLENLIEEKTGFKITDHQLKFYGLCSECQKSIANKE
>Mature_148_residues
MKQDILRSELRKRKQRMTAQRELILKAFMESGEEHMSAEEVYRKVLERRLRISKATVYRTVELLTEVGLLRKIVFRDGVV
RYELVDKGEHHHHHLVCNSCGKVIEFPEDLLDGLENLIEEKTGFKITDHQLKFYGLCSECQKSIANKE

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=35.3383458646617, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17413; Mature: 17413

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDILRSELRKRKQRMTAQRELILKAFMESGEEHMSAEEVYRKVLERRLRISKATVYRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VELLTEVGLLRKIVFRDGVVRYELVDKGEHHHHHLVCNSCGKVIEFPEDLLDGLENLIEE
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KTGFKITDHQLKFYGLCSECQKSIANKE
HCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQDILRSELRKRKQRMTAQRELILKAFMESGEEHMSAEEVYRKVLERRLRISKATVYRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VELLTEVGLLRKIVFRDGVVRYELVDKGEHHHHHLVCNSCGKVIEFPEDLLDGLENLIEE
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KTGFKITDHQLKFYGLCSECQKSIANKE
HCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]